| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | (1s,2s)-2-(1-methyl-2-oxohydrazino)-1-phenyl-1-propanol 4.99 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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82 genes differentially expressed following the CRCGN013_HEPG2_24H:F15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | 8.64482 |
| NOTCH1 | notch 1 | 6.83815 |
| SSBP2 | single-stranded DNA binding protein 2 | 6.00351 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 5.48204 |
| JADE2 | jade family PHD finger 2 | 5.47589 |
| PLS1 | plastin 1 | 5.10008 |
| STK10 | serine/threonine kinase 10 | 5.08359 |
| ABHD6 | abhydrolase domain containing 6 | 4.80091 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 4.69922 |
| KIFBP | kinesin family binding protein | 4.68726 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 4.45398 |
| MYLK | myosin light chain kinase | 4.39239 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 3.80485 |
| BAMBI | BMP and activin membrane-bound inhibitor | 3.6112 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 3.40873 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.29283 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 3.28335 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 3.15074 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 3.08237 |
| EDN1 | endothelin 1 | 3.08193 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.76908 |
| EPHA3 | EPH receptor A3 | 2.74296 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.69743 |
| CCNJL | cyclin J-like | 2.64425 |
| GATA2 | GATA binding protein 2 | 2.58875 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.51545 |
| PTGDR | prostaglandin D2 receptor (DP) | 2.42121 |
| STXBP2 | syntaxin binding protein 2 | 2.37742 |
| ITGA1 | integrin, alpha 1 | 2.37597 |
| SOCS2 | suppressor of cytokine signaling 2 | 2.33252 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.16507 |
| FZD6 | frizzled class receptor 6 | 2.10615 |
| CCPG1 | cell cycle progression 1 | 2.08122 |
| CLINT1 | clathrin interactor 1 | 2.07476 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.04765 |
| DIPK1A | divergent protein kinase domain 1A | 2.01597 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 | 2.00722 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -8.56643 |
| NUP85 | nucleoporin 85kDa | -8.53258 |
| UGDH | UDP-glucose 6-dehydrogenase | -5.21037 |
| MRPS7 | mitochondrial ribosomal protein S7 | -4.29831 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -4.00871 |
| LOC124907782 | dual specificity protein phosphatase 22 | -3.87129 |
| CAB39 | calcium binding protein 39 | -3.85493 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.77996 |
| JPT1 | Jupiter microtubule associated homolog 1 | -3.70195 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.66507 |
| MRPL58 | mitochondrial ribosomal protein L58 | -3.5801 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -3.56959 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.54294 |
| DNM1L | dynamin 1-like | -3.50522 |
| DSG2 | desmoglein 2 | -3.45639 |
| PLK1 | polo-like kinase 1 | -3.44277 |
| TMEM94 | transmembrane protein 94 | -3.14556 |
| CCDC86 | coiled-coil domain containing 86 | -3.00458 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -2.81307 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -2.74881 |
| KCTD2 | potassium channel tetramerization domain containing 2 | -2.64734 |
| SNX11 | sorting nexin 11 | -2.59897 |
| GRB2 | growth factor receptor-bound protein 2 | -2.59519 |
| SAP30BP | SAP30 binding protein | -2.54323 |
| SUMO4 | small ubiquitin-like modifier 4 | -2.5306 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.50166 |
| RGS2 | regulator of G-protein signaling 2 | -2.4996 |
| OXCT1 | 3-oxoacid CoA transferase 1 | -2.49805 |
| ACOX1 | acyl-CoA oxidase 1, palmitoyl | -2.41103 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.37724 |
| NT5C | 5', 3'-nucleotidase, cytosolic | -2.35979 |
| BLCAP | bladder cancer associated protein | -2.31568 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -2.27967 |
| BTBD1 | BTB (POZ) domain containing 1 | -2.15603 |
| GGA3 | golgi-associated, gamma adaptin ear containing, ARF binding protein 3 | -2.12747 |
| GNAS | GNAS complex locus | -2.12124 |
| CDR2L | cerebellar degeneration-related protein 2-like | -2.09787 |
| FDXR | ferredoxin reductase | -2.08904 |
| GET1 | guided entry of tail-anchored proteins factor 1 | -2.08163 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.06545 |
| SLN | sarcolipin | -2.05667 |
| UTP6 | UTP6, small subunit (SSU) processome component, homolog (yeast) | -2.0371 |
| PRPSAP1 | phosphoribosyl pyrophosphate synthetase-associated protein 1 | -2.02105 |
| ACTC1 | actin, alpha, cardiac muscle 1 | -2.00884 |
| DPP3 | dipeptidyl-peptidase 3 | -2.00504 |
