CRCGN013_HEPG2_24H:F18 Gene Set
Genes
46 genes differentially expressed following the CRCGN013_HEPG2_24H:F18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LCN2
|
lipocalin 2
|
6.75893
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
6.74371
|
|
STK10
|
serine/threonine kinase 10
|
6.72513
|
|
MAMLD1
|
mastermind-like domain containing 1
|
3.92687
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.6616
|
|
MYLK
|
myosin light chain kinase
|
3.61295
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.53605
|
|
KLHL21
|
kelch-like family member 21
|
3.17747
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.03377
|
|
UBQLN2
|
ubiquilin 2
|
2.76641
|
|
CBR3
|
carbonyl reductase 3
|
2.675
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.57814
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
2.41068
|
|
MAP7
|
microtubule-associated protein 7
|
2.38557
|
|
PRR15L
|
proline rich 15-like
|
2.35733
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
2.24956
|
|
HEATR3
|
HEAT repeat containing 3
|
2.21868
|
|
ZNF589
|
zinc finger protein 589
|
2.21272
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.21159
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.21098
|
|
ENTPD6
|
ectonucleoside triphosphate diphosphohydrolase 6 (putative)
|
2.13043
|
|
ZFYVE16
|
zinc finger, FYVE domain containing 16
|
2.11971
|
|
SFTPB
|
surfactant protein B
|
2.06433
|
|
RAB20
|
RAB20, member RAS oncogene family
|
2.06309
|
|
TCFL5
|
transcription factor-like 5 (basic helix-loop-helix)
|
2.00994
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.71071
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-6.52739
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.43833
|
|
GNAS
|
GNAS complex locus
|
-5.15354
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-4.92865
|
|
CCNB2
|
cyclin B2
|
-4.79372
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-4.59177
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.38665
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.36599
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.26732
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.21324
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.04136
|
|
CDC20
|
cell division cycle 20
|
-3.04033
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.86798
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.57321
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.50644
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.3844
|
|
ZNF586
|
zinc finger protein 586
|
-2.29175
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.22613
|
|
DNAJB6
|
DnaJ (Hsp40) homolog, subfamily B, member 6
|
-2.21707
|
|
ERCC4
|
excision repair cross-complementation group 4
|
-2.21085
|
