CRCGN013_HEPG2_24H:F22 Gene Set
Genes
42 genes differentially expressed following the CRCGN013_HEPG2_24H:F22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
5.30419
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
5.2926
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
5.28337
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
3.80726
|
|
VGLL4
|
vestigial-like family member 4
|
3.37747
|
|
NOTCH1
|
notch 1
|
3.20821
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.11882
|
|
CCDC85B
|
coiled-coil domain containing 85B
|
2.88516
|
|
CYCS
|
cytochrome c, somatic
|
2.8171
|
|
ADAT1
|
adenosine deaminase, tRNA-specific 1
|
2.72993
|
|
MEF2C
|
myocyte enhancer factor 2C
|
2.71447
|
|
TATDN2
|
TatD DNase domain containing 2
|
2.67267
|
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
2.66696
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
2.53216
|
|
MCUR1
|
mitochondrial calcium uniporter regulator 1
|
2.52185
|
|
SQOR
|
sulfide quinone oxidoreductase
|
2.32479
|
|
FOS
|
FBJ murine osteosarcoma viral oncogene homolog
|
2.21166
|
|
HLA-DRB1
|
major histocompatibility complex, class II, DR beta 1
|
2.12799
|
|
ITGAM
|
integrin, alpha M (complement component 3 receptor 3 subunit)
|
2.07942
|
|
PIH1D1
|
PIH1 domain containing 1
|
2.07075
|
|
EVL
|
Enah/Vasp-like
|
2.00799
|
|
SCAND1
|
SCAN domain containing 1
|
2.00188
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
GNAS
|
GNAS complex locus
|
-5.65031
|
|
VAT1
|
vesicle amine transport 1
|
-5.39657
|
|
GOLT1B
|
golgi transport 1B
|
-5.15905
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-4.99686
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-4.88769
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.87825
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-4.27398
|
|
SMNDC1
|
survival motor neuron domain containing 1
|
-3.27879
|
|
CDC20
|
cell division cycle 20
|
-3.08234
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-2.71482
|
|
CRK
|
v-crk avian sarcoma virus CT10 oncogene homolog
|
-2.56813
|
|
SNX11
|
sorting nexin 11
|
-2.55748
|
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding
|
-2.48957
|
|
PEG10
|
paternally expressed 10
|
-2.4334
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-2.41283
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.12365
|
|
PLK1
|
polo-like kinase 1
|
-2.09046
|
|
ANKRD10
|
ankyrin repeat domain 10
|
-2.08568
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.05462
|
|
CLDN6
|
claudin 6
|
-2.03289
|
