CRCGN013_HEPG2_24H:F23 Gene Set
Genes
59 genes differentially expressed following the CRCGN013_HEPG2_24H:F23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CHMP6
|
charged multivesicular body protein 6
|
5.22867
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
5.10583
|
|
LCN2
|
lipocalin 2
|
5.06655
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.9731
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
4.72085
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.89397
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
3.21864
|
|
TBP
|
TATA box binding protein
|
3.09607
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.92207
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.80684
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.74224
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.70983
|
|
H2BC12
|
H2B clustered histone 12
|
2.63738
|
|
MYLK
|
myosin light chain kinase
|
2.58725
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.52472
|
|
TCFL5
|
transcription factor-like 5 (basic helix-loop-helix)
|
2.50922
|
|
DNMT3A
|
DNA (cytosine-5-)-methyltransferase 3 alpha
|
2.49715
|
|
NOTCH1
|
notch 1
|
2.46466
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.44806
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
2.29279
|
|
E2F2
|
E2F transcription factor 2
|
2.28977
|
|
SYCP2
|
synaptonemal complex protein 2
|
2.25083
|
|
SCRN1
|
secernin 1
|
2.23519
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.22731
|
|
ATP11B
|
ATPase, class VI, type 11B
|
2.21632
|
|
EPHA3
|
EPH receptor A3
|
2.09759
|
|
SFTPB
|
surfactant protein B
|
2.05039
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.04027
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-5.58007
|
|
VAT1
|
vesicle amine transport 1
|
-5.09821
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-4.89369
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-4.68753
|
|
CCDC86
|
coiled-coil domain containing 86
|
-4.62565
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-4.27255
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.80695
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.38653
|
|
CCNB1
|
cyclin B1
|
-3.26474
|
|
CD58
|
CD58 molecule
|
-3.2046
|
|
CSNK1E
|
casein kinase 1, epsilon
|
-3.08889
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-2.73697
|
|
RNPS1
|
RNA binding protein S1, serine-rich domain
|
-2.70653
|
|
SCAND1
|
SCAN domain containing 1
|
-2.699
|
|
ZNF587B
|
zinc finger protein 587B
|
-2.68421
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.67666
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.66722
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-2.57836
|
|
FASTKD5
|
FAST kinase domains 5
|
-2.57732
|
|
LDHD
|
lactate dehydrogenase D
|
-2.57023
|
|
GOLT1B
|
golgi transport 1B
|
-2.56146
|
|
VSIG10
|
V-set and immunoglobulin domain containing 10
|
-2.43459
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.34952
|
|
METTL8
|
methyltransferase like 8
|
-2.23485
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.22614
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
-2.1551
|
|
NANOG
|
Nanog homeobox
|
-2.12112
|
|
PLIN2
|
perilipin 2
|
-2.11988
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.07556
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.07328
|
|
PHC1
|
polyhomeotic homolog 1 (Drosophila)
|
-2.06976
|
