CRCGN013_HEPG2_24H:F24 Gene Set
Genes
51 genes differentially expressed following the CRCGN013_HEPG2_24H:F24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
6.63701
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
6.20161
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
5.13792
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
4.6738
|
|
DHX29
|
DEAH (Asp-Glu-Ala-His) box polypeptide 29
|
4.03594
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
3.82333
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
3.52649
|
|
E2F2
|
E2F transcription factor 2
|
3.26829
|
|
RAB11FIP1
|
RAB11 family interacting protein 1 (class I)
|
3.21319
|
|
TMEM50A
|
transmembrane protein 50A
|
3.14725
|
|
LCN2
|
lipocalin 2
|
2.99563
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.92855
|
|
PRDX4
|
peroxiredoxin 4
|
2.66637
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.61818
|
|
EVL
|
Enah/Vasp-like
|
2.4965
|
|
WASF3
|
WAS protein family, member 3
|
2.40399
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
2.36729
|
|
LRP10
|
low density lipoprotein receptor-related protein 10
|
2.25064
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.17074
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.07741
|
|
NEDD4
|
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
|
2.06016
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.03432
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.6772
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-5.4316
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.98866
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-4.93706
|
|
COG2
|
component of oligomeric golgi complex 2
|
-4.90667
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-4.8963
|
|
VAT1
|
vesicle amine transport 1
|
-4.7824
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-4.04047
|
|
TUBB6
|
tubulin, beta 6 class V
|
-3.97478
|
|
GNAS
|
GNAS complex locus
|
-3.70997
|
|
DNM1L
|
dynamin 1-like
|
-3.68453
|
|
HMG20B
|
high mobility group 20B
|
-3.39228
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
-3.16411
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.99338
|
|
EGF
|
epidermal growth factor
|
-2.58956
|
|
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1
|
-2.5871
|
|
ILK
|
integrin-linked kinase
|
-2.56609
|
|
CCP110
|
centriolar coiled coil protein 110kDa
|
-2.50751
|
|
MEOX2
|
mesenchyme homeobox 2
|
-2.3919
|
|
SUOX
|
sulfite oxidase
|
-2.16809
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.16611
|
|
DNAJB6
|
DnaJ (Hsp40) homolog, subfamily B, member 6
|
-2.15665
|
|
SNX24
|
sorting nexin 24
|
-2.14699
|
|
PTPN6
|
protein tyrosine phosphatase, non-receptor type 6
|
-2.14553
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.11662
|
|
USP39
|
ubiquitin specific peptidase 39
|
-2.0458
|
|
MGAT4A
|
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
|
-2.01898
|
|
EPM2AIP1
|
EPM2A (laforin) interacting protein 1
|
-2.01656
|
|
THSD7A
|
thrombospondin, type I, domain containing 7A
|
-2.01428
|