CRCGN013_HEPG2_24H:G01 Gene Set
Genes
50 genes differentially expressed following the CRCGN013_HEPG2_24H:G01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CHMP6
|
charged multivesicular body protein 6
|
4.79683
|
|
RPL39L
|
ribosomal protein L39-like
|
4.47667
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.24016
|
|
ALDOC
|
aldolase C, fructose-bisphosphate
|
4.21201
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
4.21098
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.1085
|
|
CEP57
|
centrosomal protein 57kDa
|
3.72543
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
3.08131
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.07453
|
|
TBP
|
TATA box binding protein
|
3.05747
|
|
RAB4A
|
RAB4A, member RAS oncogene family
|
2.89458
|
|
RFNG
|
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
2.54706
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.53169
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.5107
|
|
TMEM135
|
transmembrane protein 135
|
2.49212
|
|
ANKRD49
|
ankyrin repeat domain 49
|
2.46231
|
|
WDTC1
|
WD and tetratricopeptide repeats 1
|
2.32001
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
2.31056
|
|
SULF1
|
sulfatase 1
|
2.25239
|
|
CENPX
|
centromere protein X
|
2.19561
|
|
CYCS
|
cytochrome c, somatic
|
2.11975
|
|
LYZ
|
lysozyme
|
2.03378
|
|
GPATCH8
|
G patch domain containing 8
|
2.01797
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-7.91875
|
|
GNAS
|
GNAS complex locus
|
-7.5366
|
|
ADI1
|
acireductone dioxygenase 1
|
-7.36882
|
|
CCNB2
|
cyclin B2
|
-5.97986
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-5.06972
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.54677
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-4.05912
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-3.90047
|
|
FASTKD5
|
FAST kinase domains 5
|
-3.73547
|
|
CCNB1
|
cyclin B1
|
-3.58533
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.15982
|
|
CTNND1
|
catenin (cadherin-associated protein), delta 1
|
-3.11966
|
|
TOR1A
|
torsin family 1, member A (torsin A)
|
-3.01238
|
|
TES
|
testin LIM domain protein
|
-2.68045
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-2.66108
|
|
CAB39
|
calcium binding protein 39
|
-2.53117
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.31552
|
|
LAMA5
|
laminin, alpha 5
|
-2.28344
|
|
TCTN1
|
tectonic family member 1
|
-2.26623
|
|
HIVEP1
|
human immunodeficiency virus type I enhancer binding protein 1
|
-2.16921
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-2.15966
|
|
LY86
|
lymphocyte antigen 86
|
-2.15218
|
|
TJP2
|
tight junction protein 2
|
-2.15166
|
|
TPCN1
|
two pore segment channel 1
|
-2.09354
|
|
ATP1A2
|
ATPase, Na+/K+ transporting, alpha 2 polypeptide
|
-2.05649
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-2.03332
|
|
KRT5
|
keratin 5, type II
|
-2.02855
|
