| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | choline chloride 10.05 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
64 genes differentially expressed following the CRCGN013_HEPG2_24H:G03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPARG | peroxisome proliferator-activated receptor gamma | 7.8208 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.4314 |
| MEF2C | myocyte enhancer factor 2C | 4.03151 |
| SSBP2 | single-stranded DNA binding protein 2 | 4.00747 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 3.72136 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.62711 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 3.58909 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 3.5297 |
| SIRT3 | sirtuin 3 | 3.31419 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.26828 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 3.20392 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.08284 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.03958 |
| EVL | Enah/Vasp-like | 2.77432 |
| GATA2 | GATA binding protein 2 | 2.76393 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.7018 |
| ADAM10 | ADAM metallopeptidase domain 10 | 2.32019 |
| SFTPB | surfactant protein B | 2.29991 |
| EXOC5 | exocyst complex component 5 | 2.28187 |
| HSPB3 | heat shock 27kDa protein 3 | 2.26902 |
| EGF | epidermal growth factor | 2.2519 |
| LCN2 | lipocalin 2 | 2.23493 |
| SNX13 | sorting nexin 13 | 2.22243 |
| TNNC2 | troponin C type 2 (fast) | 2.18305 |
| MBNL1 | muscleblind-like splicing regulator 1 | 2.15228 |
| RYR1 | ryanodine receptor 1 (skeletal) | 2.15226 |
| MYL11 | myosin light chain 11 | 2.12632 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 2.1111 |
| STXBP2 | syntaxin binding protein 2 | 2.0735 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 2.07084 |
| RRAGA | Ras-related GTP binding A | 2.04887 |
| PTK2 | protein tyrosine kinase 2 | 2.04717 |
| HDAC5 | histone deacetylase 5 | 2.03841 |
| CUL4B | cullin 4B | 2.03624 |
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 | 2.01028 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 2.00883 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -5.83362 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -5.3649 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -4.4463 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -4.17434 |
| ZNF586 | zinc finger protein 586 | -3.88424 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.83101 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.77177 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.46941 |
| RPS5 | ribosomal protein S5 | -3.31362 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -3.2024 |
| TXNDC9 | thioredoxin domain containing 9 | -3.05392 |
| UBE3C | ubiquitin protein ligase E3C | -2.97315 |
| GNAS | GNAS complex locus | -2.74989 |
| CAB39 | calcium binding protein 39 | -2.67911 |
| CCNB2 | cyclin B2 | -2.59157 |
| SNX11 | sorting nexin 11 | -2.58651 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -2.47823 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -2.46936 |
| TOB1 | transducer of ERBB2, 1 | -2.44957 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.35911 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -2.32744 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.14742 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -2.13949 |
| ZNF134 | zinc finger protein 134 | -2.08219 |
| TRAPPC6A | trafficking protein particle complex 6A | -2.05679 |
| ZNF587B | zinc finger protein 587B | -2.04597 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -2.0382 |
| LRRN3 | leucine rich repeat neuronal 3 | -2.02348 |
