CRCGN013_HEPG2_24H:G04 Gene Set
Genes
44 genes differentially expressed following the CRCGN013_HEPG2_24H:G04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.08779
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
3.85888
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.52638
|
|
CHN1
|
chimerin 1
|
3.31277
|
|
CEBPZ
|
CCAAT/enhancer binding protein (C/EBP), zeta
|
3.24789
|
|
DNAJB2
|
DnaJ (Hsp40) homolog, subfamily B, member 2
|
3.13265
|
|
PDLIM1
|
PDZ and LIM domain 1
|
3.11659
|
|
EAPP
|
E2F-associated phosphoprotein
|
2.79681
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.75744
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
2.47834
|
|
IQGAP1
|
IQ motif containing GTPase activating protein 1
|
2.47639
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
2.47267
|
|
JADE2
|
jade family PHD finger 2
|
2.36473
|
|
KIF20A
|
kinesin family member 20A
|
2.32671
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
2.27026
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.15641
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.09132
|
|
ABHD4
|
abhydrolase domain containing 4
|
2.0905
|
|
RAB21
|
RAB21, member RAS oncogene family
|
2.05618
|
|
DUSP11
|
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
|
2.01888
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-7.2357
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-4.40756
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-4.38974
|
|
ABCF1
|
ATP-binding cassette, sub-family F (GCN20), member 1
|
-3.61864
|
|
ENOPH1
|
enolase-phosphatase 1
|
-3.19429
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.19052
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-2.98115
|
|
MAP7
|
microtubule-associated protein 7
|
-2.86882
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.85339
|
|
GDF15
|
growth differentiation factor 15
|
-2.81781
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.74731
|
|
LAP3
|
leucine aminopeptidase 3
|
-2.6621
|
|
EGF
|
epidermal growth factor
|
-2.55982
|
|
PSRC1
|
proline/serine-rich coiled-coil 1
|
-2.42803
|
|
ZW10
|
zw10 kinetochore protein
|
-2.39058
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.30417
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.28976
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-2.28121
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.26684
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.15587
|
|
PLXDC1
|
plexin domain containing 1
|
-2.08871
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.06427
|
|
TSPAN15
|
tetraspanin 15
|
-2.05129
|
|
GRB7
|
growth factor receptor-bound protein 7
|
-2.02781
|
