CRCGN013_HEPG2_24H:G05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description choline chloride 2.51 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

21 genes differentially expressed following the CRCGN013_HEPG2_24H:G05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 4.6699
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 3.84938
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 3.6981
H2BC12 H2B clustered histone 12 2.84543
TXNL4B thioredoxin-like 4B 2.81773
AMDHD2 amidohydrolase domain containing 2 2.6598
CYCS cytochrome c, somatic 2.06293

decreased expression

Symbol Name Standardized Value
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -8.95502
PCNA proliferating cell nuclear antigen -6.15025
LDHD lactate dehydrogenase D -5.03042
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -4.55149
EGF epidermal growth factor -3.88019
FGFR4 fibroblast growth factor receptor 4 -3.52519
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -3.41762
DHRS7 dehydrogenase/reductase (SDR family) member 7 -3.29076
MAPK13 mitogen-activated protein kinase 13 -3.24487
GDF15 growth differentiation factor 15 -2.82591
ZNF586 zinc finger protein 586 -2.77746
RAI14 retinoic acid induced 14 -2.62804
ADI1 acireductone dioxygenase 1 -2.58532
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.26505