CRCGN013_HEPG2_24H:G05 Gene Set
Genes
21 genes differentially expressed following the CRCGN013_HEPG2_24H:G05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.6699
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
3.84938
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
3.6981
|
|
H2BC12
|
H2B clustered histone 12
|
2.84543
|
|
TXNL4B
|
thioredoxin-like 4B
|
2.81773
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
2.6598
|
|
CYCS
|
cytochrome c, somatic
|
2.06293
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-8.95502
|
|
PCNA
|
proliferating cell nuclear antigen
|
-6.15025
|
|
LDHD
|
lactate dehydrogenase D
|
-5.03042
|
|
STUB1
|
STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
|
-4.55149
|
|
EGF
|
epidermal growth factor
|
-3.88019
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.52519
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-3.41762
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.29076
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.24487
|
|
GDF15
|
growth differentiation factor 15
|
-2.82591
|
|
ZNF586
|
zinc finger protein 586
|
-2.77746
|
|
RAI14
|
retinoic acid induced 14
|
-2.62804
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.58532
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.26505
|