CRCGN013_HEPG2_24H:G06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description choline chloride 1.26 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

32 genes differentially expressed following the CRCGN013_HEPG2_24H:G06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
LCN2 lipocalin 2 6.31215
NOSIP nitric oxide synthase interacting protein 3.97891
PRR15L proline rich 15-like 3.73589
CCDC92 coiled-coil domain containing 92 3.26158
PPARG peroxisome proliferator-activated receptor gamma 3.04502
KLHL9 kelch-like family member 9 3.03391
UBQLN2 ubiquilin 2 2.6601
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 2.54901
SSBP2 single-stranded DNA binding protein 2 2.4676
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.43268
SNX7 sorting nexin 7 2.33812
EPHA3 EPH receptor A3 2.29319
MAP7 microtubule-associated protein 7 2.27503
PRKCH protein kinase C, eta 2.26363
CHN1 chimerin 1 2.14726
RPP38 ribonuclease P/MRP 38kDa subunit 2.14077
BACE2 beta-site APP-cleaving enzyme 2 2.06454

decreased expression

Symbol Name Standardized Value
OXA1L oxidase (cytochrome c) assembly 1-like -5.29176
MAPK13 mitogen-activated protein kinase 13 -5.17922
TLCD3A TLC domain containing 3A -4.12296
DERA deoxyribose-phosphate aldolase (putative) -3.6352
LYPLA1 lysophospholipase I -3.44677
ZNF586 zinc finger protein 586 -3.22311
TSPAN4 tetraspanin 4 -2.92617
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.89527
TLR4 toll-like receptor 4 -2.84405
UGDH UDP-glucose 6-dehydrogenase -2.72891
SLC35F2 solute carrier family 35, member F2 -2.61842
PLK1 polo-like kinase 1 -2.49562
ELAC2 elaC ribonuclease Z 2 -2.22901
SNX11 sorting nexin 11 -2.17922
GNAS GNAS complex locus -2.00674