CRCGN013_HEPG2_24H:G07 Gene Set
Genes
48 genes differentially expressed following the CRCGN013_HEPG2_24H:G07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.40213
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
4.37348
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
4.13584
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.84689
|
|
E2F2
|
E2F transcription factor 2
|
3.78697
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
3.73569
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.62246
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.61692
|
|
PRR15L
|
proline rich 15-like
|
3.5008
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.30396
|
|
JADE2
|
jade family PHD finger 2
|
3.26103
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.18315
|
|
SATB1
|
SATB homeobox 1
|
3.14659
|
|
CD40
|
CD40 molecule, TNF receptor superfamily member 5
|
2.89458
|
|
LCN2
|
lipocalin 2
|
2.84783
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.74734
|
|
EPHA3
|
EPH receptor A3
|
2.39612
|
|
IFIT1
|
interferon-induced protein with tetratricopeptide repeats 1
|
2.22628
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.19499
|
|
TCN2
|
transcobalamin II
|
2.17438
|
|
IFI44
|
interferon-induced protein 44
|
2.16555
|
|
CASP10
|
caspase 10, apoptosis-related cysteine peptidase
|
2.07947
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
2.04763
|
|
MYLK
|
myosin light chain kinase
|
2.04297
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ADI1
|
acireductone dioxygenase 1
|
-7.83907
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-4.51396
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-4.10549
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.99869
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-3.98957
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.91486
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.7507
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.20597
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-3.09917
|
|
EGF
|
epidermal growth factor
|
-3.07371
|
|
WASHC4
|
WASH complex subunit 4
|
-2.74383
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-2.73185
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.68401
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-2.61629
|
|
MTA1
|
metastasis associated 1
|
-2.41525
|
|
ASAH1
|
N-acylsphingosine amidohydrolase (acid ceramidase) 1
|
-2.40302
|
|
MAP7
|
microtubule-associated protein 7
|
-2.32324
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.31376
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.25081
|
|
CERS2
|
ceramide synthase 2
|
-2.14572
|
|
NUP85
|
nucleoporin 85kDa
|
-2.13894
|
|
PAEP
|
progestagen-associated endometrial protein
|
-2.11134
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.02941
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.02433
|
