CRCGN013_HEPG2_24H:G10 Gene Set
Genes
50 genes differentially expressed following the CRCGN013_HEPG2_24H:G10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
SQOR
|
sulfide quinone oxidoreductase
|
4.97938
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.82807
|
|
LCN2
|
lipocalin 2
|
4.66034
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
4.61214
|
|
UBQLN2
|
ubiquilin 2
|
4.56153
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.04649
|
|
LOC122526780
|
uncharacterized LOC122526780
|
4.02334
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
3.83698
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.71763
|
|
PRKCQ
|
protein kinase C, theta
|
3.43588
|
|
PHKA1
|
phosphorylase kinase, alpha 1 (muscle)
|
3.34268
|
|
RRAGA
|
Ras-related GTP binding A
|
3.28694
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.18565
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
3.09733
|
|
CCNF
|
cyclin F
|
2.95294
|
|
TCFL5
|
transcription factor-like 5 (basic helix-loop-helix)
|
2.62284
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.25695
|
|
CDC73
|
cell division cycle 73
|
2.25353
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.22173
|
|
COG4
|
component of oligomeric golgi complex 4
|
2.21814
|
|
WDTC1
|
WD and tetratricopeptide repeats 1
|
2.11827
|
|
JADE2
|
jade family PHD finger 2
|
2.10484
|
|
RPH3A
|
rabphilin 3A
|
2.06209
|
|
TBPL1
|
TBP-like 1
|
2.05734
|
|
ACTN2
|
actinin, alpha 2
|
2.04705
|
|
MCM3
|
minichromosome maintenance complex component 3
|
2.04659
|
|
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
|
2.02639
|
|
PKNOX2
|
PBX/knotted 1 homeobox 2
|
2.02391
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-8.84994
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-4.73141
|
|
SNX6
|
sorting nexin 6
|
-4.5376
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.53495
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.36899
|
|
LDHD
|
lactate dehydrogenase D
|
-4.32375
|
|
MAP7
|
microtubule-associated protein 7
|
-4.08295
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.74973
|
|
CASP3
|
caspase 3, apoptosis-related cysteine peptidase
|
-3.6754
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.45297
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-3.3192
|
|
WDR7
|
WD repeat domain 7
|
-2.90261
|
|
SLC2A6
|
solute carrier family 2 (facilitated glucose transporter), member 6
|
-2.86934
|
|
NR2F6
|
nuclear receptor subfamily 2, group F, member 6
|
-2.80828
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.64074
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.61925
|
|
RIPK1
|
receptor (TNFRSF)-interacting serine-threonine kinase 1
|
-2.59992
|
|
ACLY
|
ATP citrate lyase
|
-2.39091
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-2.13489
|
|
TSPAN1
|
tetraspanin 1
|
-2.10426
|
|
ZNRF2
|
zinc and ring finger 2, E3 ubiquitin protein ligase
|
-2.02843
|
|
STK25
|
serine/threonine kinase 25
|
-2.01921
|
