CRCGN013_HEPG2_24H:G11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description sodium-nitrite 2.56 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

30 genes differentially expressed following the CRCGN013_HEPG2_24H:G11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
LCN2 lipocalin 2 6.54873
DYNLT3 dynein, light chain, Tctex-type 3 6.27657
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 5.99845
MAP3K4 mitogen-activated protein kinase kinase kinase 4 4.85339
PPARG peroxisome proliferator-activated receptor gamma 3.55773
CRTAP cartilage associated protein 3.17408
PROS1 protein S (alpha) 2.92196
GSTZ1 glutathione S-transferase zeta 1 2.77115
RRAGA Ras-related GTP binding A 2.44622
ADGRE5 adhesion G protein-coupled receptor E5 2.42786
GPER1 G protein-coupled estrogen receptor 1 2.37826
GFOD1 glucose-fructose oxidoreductase domain containing 1 2.3536
RAB21 RAB21, member RAS oncogene family 2.34601
NOTCH1 notch 1 2.28895
WASF3 WAS protein family, member 3 2.14664
SSBP2 single-stranded DNA binding protein 2 2.04123
PRKCH protein kinase C, eta 2.01607

decreased expression

Symbol Name Standardized Value
PCNA proliferating cell nuclear antigen -5.30364
HMG20B high mobility group 20B -4.68413
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -3.88641
TRIB3 tribbles pseudokinase 3 -3.80714
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.50163
SLC35F2 solute carrier family 35, member F2 -3.35732
CHMP4B charged multivesicular body protein 4B -2.9385
TLCD3A TLC domain containing 3A -2.75324
RBM15 RNA binding motif protein 15 -2.66315
CCNB2 cyclin B2 -2.56733
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -2.56113
ISOC1 isochorismatase domain containing 1 -2.4815
FASTKD5 FAST kinase domains 5 -2.40481