CRCGN013_HEPG2_24H:G20 Gene Set
Genes
41 genes differentially expressed following the CRCGN013_HEPG2_24H:G20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
6.58378
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
5.75994
|
|
MYLK
|
myosin light chain kinase
|
4.70831
|
|
LCN2
|
lipocalin 2
|
4.36425
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.972
|
|
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
|
3.85494
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.85482
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
3.47335
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
3.44672
|
|
CCNH
|
cyclin H
|
3.14458
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.85118
|
|
SCRN1
|
secernin 1
|
2.77029
|
|
VGLL4
|
vestigial-like family member 4
|
2.73133
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.71881
|
|
JADE2
|
jade family PHD finger 2
|
2.68848
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.65616
|
|
CYCS
|
cytochrome c, somatic
|
2.63428
|
|
MCUR1
|
mitochondrial calcium uniporter regulator 1
|
2.63032
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
2.20087
|
|
CHAC1
|
ChaC glutathione-specific gamma-glutamylcyclotransferase 1
|
2.19914
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.15079
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.37159
|
|
TMEM109
|
transmembrane protein 109
|
-4.73039
|
|
ADI1
|
acireductone dioxygenase 1
|
-4.15884
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-4.0257
|
|
FASTKD5
|
FAST kinase domains 5
|
-4.00061
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-3.97787
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.91302
|
|
CASP3
|
caspase 3, apoptosis-related cysteine peptidase
|
-3.84305
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.7981
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.61327
|
|
CCNB2
|
cyclin B2
|
-3.46214
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.36831
|
|
GNAS
|
GNAS complex locus
|
-2.96391
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.83001
|
|
TENT4A
|
terminal nucleotidyltransferase 4A
|
-2.58573
|
|
TLR4
|
toll-like receptor 4
|
-2.3557
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.34534
|
|
CRK
|
v-crk avian sarcoma virus CT10 oncogene homolog
|
-2.30007
|
|
RPGR
|
retinitis pigmentosa GTPase regulator
|
-2.21807
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.07662
|
