CRCGN013_HEPG2_24H:G21 Gene Set
Genes
42 genes differentially expressed following the CRCGN013_HEPG2_24H:G21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CHN1
|
chimerin 1
|
5.6385
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
5.48664
|
|
UBQLN2
|
ubiquilin 2
|
5.24364
|
|
E2F2
|
E2F transcription factor 2
|
4.61593
|
|
LCN2
|
lipocalin 2
|
3.94476
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
3.92304
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
3.53335
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.40753
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
3.07154
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.00293
|
|
MMP1
|
matrix metallopeptidase 1
|
2.9454
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
2.83757
|
|
CHEK2
|
checkpoint kinase 2
|
2.58869
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.54026
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.53231
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.50734
|
|
TCTA
|
T-cell leukemia translocation altered
|
2.42468
|
|
DNAJB2
|
DnaJ (Hsp40) homolog, subfamily B, member 2
|
2.35371
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.25324
|
|
FPGS
|
folylpolyglutamate synthase
|
2.24661
|
|
DNMT3A
|
DNA (cytosine-5-)-methyltransferase 3 alpha
|
2.24556
|
|
RAB11FIP1
|
RAB11 family interacting protein 1 (class I)
|
2.06605
|
|
CHAC1
|
ChaC glutathione-specific gamma-glutamylcyclotransferase 1
|
2.03679
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
GNAS
|
GNAS complex locus
|
-5.48258
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-5.05892
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-4.72874
|
|
ENOPH1
|
enolase-phosphatase 1
|
-4.65981
|
|
TLCD3A
|
TLC domain containing 3A
|
-4.62727
|
|
ZNF586
|
zinc finger protein 586
|
-4.11817
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.85813
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.73889
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.08242
|
|
G3BP1
|
GTPase activating protein (SH3 domain) binding protein 1
|
-2.99557
|
|
HMG20B
|
high mobility group 20B
|
-2.86209
|
|
CCNB2
|
cyclin B2
|
-2.796
|
|
ABCF1
|
ATP-binding cassette, sub-family F (GCN20), member 1
|
-2.41212
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-2.31284
|
|
LAP3
|
leucine aminopeptidase 3
|
-2.28134
|
|
PAEP
|
progestagen-associated endometrial protein
|
-2.25136
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.199
|
|
CD320
|
CD320 molecule
|
-2.13512
|
|
FHL2
|
four and a half LIM domains 2
|
-2.05826
|
