CRCGN013_HEPG2_24H:G22 Gene Set
Genes
46 genes differentially expressed following the CRCGN013_HEPG2_24H:G22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
8.70153
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
7.4387
|
|
CHN1
|
chimerin 1
|
4.95031
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.84233
|
|
CYCS
|
cytochrome c, somatic
|
4.57685
|
|
MOK
|
MOK protein kinase
|
4.05749
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
3.97805
|
|
SLC25A14
|
solute carrier family 25 (mitochondrial carrier, brain), member 14
|
3.81234
|
|
VGLL4
|
vestigial-like family member 4
|
3.71678
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.59164
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
3.21739
|
|
LSR
|
lipolysis stimulated lipoprotein receptor
|
3.10095
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.92254
|
|
TCFL5
|
transcription factor-like 5 (basic helix-loop-helix)
|
2.9225
|
|
GRB10
|
growth factor receptor-bound protein 10
|
2.84197
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.79094
|
|
SLC27A3
|
solute carrier family 27 (fatty acid transporter), member 3
|
2.714
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.37657
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.22064
|
|
KLHL9
|
kelch-like family member 9
|
2.14576
|
|
ZFP36
|
ZFP36 ring finger protein
|
2.13473
|
|
TMSB15C
|
thymosin beta 15C
|
2.08865
|
|
SFTPB
|
surfactant protein B
|
2.06079
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.31151
|
|
DUSP11
|
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
|
-5.01703
|
|
ZNF586
|
zinc finger protein 586
|
-4.98252
|
|
MAP7
|
microtubule-associated protein 7
|
-4.27486
|
|
CCNB2
|
cyclin B2
|
-4.17313
|
|
PEG10
|
paternally expressed 10
|
-4.10882
|
|
WASHC4
|
WASH complex subunit 4
|
-4.00346
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-3.85056
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.68575
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.68152
|
|
CPSF4
|
cleavage and polyadenylation specific factor 4, 30kDa
|
-3.15925
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-3.06807
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.90269
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.8986
|
|
DNTTIP2
|
deoxynucleotidyltransferase, terminal, interacting protein 2
|
-2.73776
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.44567
|
|
PTDSS2
|
phosphatidylserine synthase 2
|
-2.36467
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.34555
|
|
PDZD2
|
PDZ domain containing 2
|
-2.33546
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.26882
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.26546
|
|
KLK8
|
kallikrein-related peptidase 8
|
-2.11757
|
|
HSD17B10
|
hydroxysteroid (17-beta) dehydrogenase 10
|
-2.06736
|
