CRCGN013_HEPG2_24H:G24 Gene Set
Genes
40 genes differentially expressed following the CRCGN013_HEPG2_24H:G24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.99726
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
4.71866
|
|
CHMP6
|
charged multivesicular body protein 6
|
4.30058
|
|
TBP
|
TATA box binding protein
|
4.19492
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.9328
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.58202
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
3.42648
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.26759
|
|
LCN2
|
lipocalin 2
|
2.90077
|
|
GATM
|
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
|
2.73838
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
2.73013
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
2.55401
|
|
GPATCH8
|
G patch domain containing 8
|
2.51754
|
|
IGLL1
|
immunoglobulin lambda-like polypeptide 1
|
2.32685
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.27838
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.17782
|
|
SERPINE2
|
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
|
2.12983
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CHMP4B
|
charged multivesicular body protein 4B
|
-6.65006
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-5.8812
|
|
LDHD
|
lactate dehydrogenase D
|
-5.01506
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-4.45375
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-4.4264
|
|
CCNB1
|
cyclin B1
|
-4.37053
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.17087
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-3.59558
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.49065
|
|
GNAS
|
GNAS complex locus
|
-3.38505
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.11803
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.83604
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.78225
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.63844
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.53404
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.50419
|
|
CDC20
|
cell division cycle 20
|
-2.42193
|
|
WASHC4
|
WASH complex subunit 4
|
-2.22544
|
|
FASTKD5
|
FAST kinase domains 5
|
-2.11827
|
|
FKBP3
|
FK506 binding protein 3, 25kDa
|
-2.09898
|
|
KIF3C
|
kinesin family member 3C
|
-2.07146
|
|
MSX1
|
msh homeobox 1
|
-2.0526
|
|
JMJD1C
|
jumonji domain containing 1C
|
-2.01447
|
