| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | methacrylonitrile 20.9 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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80 genes differentially expressed following the CRCGN013_HEPG2_24H:H02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 5.47965 |
| UBQLN2 | ubiquilin 2 | 5.10185 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 4.65565 |
| CEP57 | centrosomal protein 57kDa | 4.09714 |
| CTSL | cathepsin L | 4.06735 |
| SFTPB | surfactant protein B | 3.7347 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 3.6386 |
| TESK1 | testis-specific kinase 1 | 3.1384 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 2.8356 |
| CCNF | cyclin F | 2.8062 |
| CERK | ceramide kinase | 2.6881 |
| EGF | epidermal growth factor | 2.6793 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | 2.47595 |
| RNFT1-DT | RNFT1 divergent transcript | 2.4259 |
| TPD52L2 | tumor protein D52-like 2 | 2.41525 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 2.3996 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.38562 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.38045 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 2.35025 |
| SMUG1 | single-strand-selective monofunctional uracil-DNA glycosylase 1 | 2.35 |
| AAMP | angio-associated, migratory cell protein | 2.30905 |
| NTAN1 | N-terminal asparagine amidase | 2.2646 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.2621 |
| ZNF263 | zinc finger protein 263 | 2.25845 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | 2.2573 |
| PIGG | phosphatidylinositol glycan anchor biosynthesis, class G | 2.24695 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 | 2.20595 |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 | 2.1903 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.17598 |
| GRID1 | glutamate receptor, ionotropic, delta 1 | 2.1452 |
| MIS18BP1 | MIS18 binding protein 1 | 2.1383 |
| ETNK2 | ethanolamine kinase 2 | 2.11735 |
| CRTAP | cartilage associated protein | 2.0934 |
| PRDX5 | peroxiredoxin 5 | 2.0775 |
| MMP2 | matrix metallopeptidase 2 | 2.06395 |
| SEPHS2 | selenophosphate synthetase 2 | 2.059 |
| CCNH | cyclin H | 2.054 |
| SLC2A4RG | SLC2A4 regulator | 2.05205 |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 | 2.04485 |
| SNX7 | sorting nexin 7 | 2.0306 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -6.7137 |
| CDC20 | cell division cycle 20 | -5.6002 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -5.56885 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -5.16465 |
| LDHD | lactate dehydrogenase D | -5.14795 |
| SCAND1 | SCAN domain containing 1 | -5.115 |
| ADI1 | acireductone dioxygenase 1 | -5.00285 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -5.00275 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -5.0 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -4.8062 |
| GTPBP8 | GTP-binding protein 8 (putative) | -4.8013 |
| CD320 | CD320 molecule | -4.7035 |
| MAPK13 | mitogen-activated protein kinase 13 | -4.08765 |
| TLR4 | toll-like receptor 4 | -3.5323 |
| TLCD3A | TLC domain containing 3A | -3.51975 |
| PCNA | proliferating cell nuclear antigen | -3.34885 |
| HEATR1 | HEAT repeat containing 1 | -3.32635 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.1493 |
| CHEK1 | checkpoint kinase 1 | -2.968 |
| WASHC4 | WASH complex subunit 4 | -2.53842 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -2.508 |
| VDAC1 | voltage-dependent anion channel 1 | -2.50323 |
| CZIB | CXXC motif containing zinc binding protein | -2.4214 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 | -2.40785 |
| EREG | epiregulin | -2.4075 |
| ARHGAP22 | Rho GTPase activating protein 22 | -2.39145 |
| TES | testin LIM domain protein | -2.38238 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -2.3316 |
| PDCD1LG2 | programmed cell death 1 ligand 2 | -2.25925 |
| CTC1 | CTS telomere maintenance complex component 1 | -2.2524 |
| CYBA | cytochrome b-245, alpha polypeptide | -2.23195 |
| LMTK1 | lemur tail kinase 1 | -2.17305 |
| MYL3 | myosin, light chain 3, alkali; ventricular, skeletal, slow | -2.14645 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 | -2.11375 |
| PCDH9 | protocadherin 9 | -2.0877 |
| RIPOR1 | RHO family interacting cell polarization regulator 1 | -2.08515 |
| HRC | histidine rich calcium binding protein | -2.08195 |
| KAZN | kazrin, periplakin interacting protein | -2.06798 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.065 |
| KRT34 | keratin 34, type I | -2.0239 |
