CRCGN013_HEPG2_24H:H09 Gene Set
Genes
33 genes differentially expressed following the CRCGN013_HEPG2_24H:H09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
E2F2
|
E2F transcription factor 2
|
4.10196
|
|
CEP57
|
centrosomal protein 57kDa
|
3.67961
|
|
NOTCH1
|
notch 1
|
3.64505
|
|
RAB11FIP1
|
RAB11 family interacting protein 1 (class I)
|
3.46482
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
3.35754
|
|
STK10
|
serine/threonine kinase 10
|
3.3236
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.15147
|
|
SLC25A14
|
solute carrier family 25 (mitochondrial carrier, brain), member 14
|
2.66862
|
|
TBPL1
|
TBP-like 1
|
2.61067
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.60675
|
|
PRR15L
|
proline rich 15-like
|
2.52619
|
|
LRP10
|
low density lipoprotein receptor-related protein 10
|
2.43913
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.35645
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
2.01605
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-7.38635
|
|
CCNB2
|
cyclin B2
|
-6.23661
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-4.35144
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-4.18007
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.84236
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.68993
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.49795
|
|
CDC20
|
cell division cycle 20
|
-3.35411
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-3.31187
|
|
CASP3
|
caspase 3, apoptosis-related cysteine peptidase
|
-3.30505
|
|
HEATR1
|
HEAT repeat containing 1
|
-3.13582
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.05212
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.96959
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.76148
|
|
GNAS
|
GNAS complex locus
|
-2.67288
|
|
ID2
|
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
|
-2.63492
|
|
CCP110
|
centriolar coiled coil protein 110kDa
|
-2.29021
|
|
DCK
|
deoxycytidine kinase
|
-2.14261
|
|
EXT1
|
exostosin glycosyltransferase 1
|
-2.02966
|