| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 1-[2,2-dichloro-1-(4-ethylphenyl)ethyl]-4-ethylbenzene 5.08 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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49 genes differentially expressed following the CRCGN013_HEPG2_24H:H10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NOTCH1 | notch 1 | 7.97503 |
| LCN2 | lipocalin 2 | 6.74038 |
| CHN1 | chimerin 1 | 5.98842 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 4.15308 |
| HOXA10 | homeobox A10 | 4.07208 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 3.959 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 3.73214 |
| AMDHD2 | amidohydrolase domain containing 2 | 3.61255 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.39447 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 3.34976 |
| STK10 | serine/threonine kinase 10 | 3.3203 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.16598 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.97408 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 2.89983 |
| PLSCR1 | phospholipid scramblase 1 | 2.88514 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 2.87172 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | 2.60555 |
| WASF3 | WAS protein family, member 3 | 2.58369 |
| DCUN1D1 | DCN1, defective in cullin neddylation 1, domain containing 1 | 2.40083 |
| SLCO1C1 | solute carrier organic anion transporter family, member 1C1 | 2.28488 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.21216 |
| TCTA | T-cell leukemia translocation altered | 2.19966 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.13545 |
| UFM1 | ubiquitin-fold modifier 1 | 2.10993 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 2.04902 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 | 2.01641 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.48671 |
| PGRMC1 | progesterone receptor membrane component 1 | -4.51637 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.61451 |
| TES | testin LIM domain protein | -3.59982 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -3.52323 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -3.48356 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.33625 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -2.85048 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -2.72404 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -2.63407 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.40535 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -2.36878 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.33407 |
| CCNB1 | cyclin B1 | -2.30124 |
| CCNB2 | cyclin B2 | -2.23876 |
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 | -2.22154 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -2.17929 |
| CXADR | coxsackie virus and adenovirus receptor | -2.11721 |
| H2AC7 | H2A clustered histone 7 | -2.07686 |
| H2BC9 | H2B clustered histone 9 | -2.06416 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.05535 |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator | -2.03978 |
| MSH5 | mutS homolog 5 | -2.03038 |
