CRCGN013_HEPG2_24H:H16 Gene Set
Genes
48 genes differentially expressed following the CRCGN013_HEPG2_24H:H16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
9.52906
|
|
LCN2
|
lipocalin 2
|
6.27561
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
6.16164
|
|
CGRRF1
|
cell growth regulator with ring finger domain 1
|
4.10534
|
|
RPL39L
|
ribosomal protein L39-like
|
3.81794
|
|
CHN1
|
chimerin 1
|
3.65274
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.52673
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
3.39822
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.2492
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
3.18567
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.00986
|
|
MOK
|
MOK protein kinase
|
2.8517
|
|
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3
|
2.80654
|
|
TIMP2
|
TIMP metallopeptidase inhibitor 2
|
2.69336
|
|
MYLK
|
myosin light chain kinase
|
2.67387
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
2.60612
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
2.53127
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.48268
|
|
NOTCH1
|
notch 1
|
2.39829
|
|
HDAC2
|
histone deacetylase 2
|
2.3802
|
|
RRP12
|
ribosomal RNA processing 12 homolog (S. cerevisiae)
|
2.37049
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.32576
|
|
EVL
|
Enah/Vasp-like
|
2.22838
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.21932
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.2076
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
GNAS
|
GNAS complex locus
|
-7.5203
|
|
ZNF586
|
zinc finger protein 586
|
-5.24349
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-5.20069
|
|
PCNA
|
proliferating cell nuclear antigen
|
-5.1574
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.62172
|
|
ISOC1
|
isochorismatase domain containing 1
|
-3.59577
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.58881
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.55668
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.26549
|
|
RGS2
|
regulator of G-protein signaling 2
|
-3.0655
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.98821
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.96121
|
|
CCNB2
|
cyclin B2
|
-2.8509
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.82211
|
|
EGF
|
epidermal growth factor
|
-2.7828
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.76663
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.52058
|
|
GOLT1B
|
golgi transport 1B
|
-2.41041
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.35931
|
|
BLCAP
|
bladder cancer associated protein
|
-2.34717
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.3216
|
|
TCERG1
|
transcription elongation regulator 1
|
-2.30573
|
|
WDR33
|
WD repeat domain 33
|
-2.02172
|
