CRCGN013_HEPG2_24H:I01 Gene Set
Genes
52 genes differentially expressed following the CRCGN013_HEPG2_24H:I01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
6.35174
|
|
RRAGA
|
Ras-related GTP binding A
|
4.24193
|
|
CCDC85B
|
coiled-coil domain containing 85B
|
3.82872
|
|
CISD1
|
CDGSH iron sulfur domain 1
|
3.66942
|
|
NOTCH1
|
notch 1
|
3.59267
|
|
UBQLN2
|
ubiquilin 2
|
3.54167
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.52383
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.4528
|
|
LCN2
|
lipocalin 2
|
3.2981
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.27343
|
|
CYCS
|
cytochrome c, somatic
|
3.2567
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.24635
|
|
ADAT1
|
adenosine deaminase, tRNA-specific 1
|
2.99149
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
2.91968
|
|
CBR3
|
carbonyl reductase 3
|
2.70865
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.67484
|
|
CCNH
|
cyclin H
|
2.57662
|
|
HOXA10
|
homeobox A10
|
2.50292
|
|
TBP
|
TATA box binding protein
|
2.46878
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.42048
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.39043
|
|
EVL
|
Enah/Vasp-like
|
2.37862
|
|
GFOD1
|
glucose-fructose oxidoreductase domain containing 1
|
2.37766
|
|
MMP1
|
matrix metallopeptidase 1
|
2.3321
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.32355
|
|
CTSL
|
cathepsin L
|
2.1568
|
|
SFTPB
|
surfactant protein B
|
2.11403
|
|
VGLL4
|
vestigial-like family member 4
|
2.11165
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.10999
|
|
MUC4
|
mucin 4, cell surface associated
|
2.0639
|
|
ABHD3
|
abhydrolase domain containing 3
|
2.02873
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-6.98943
|
|
ZNF586
|
zinc finger protein 586
|
-6.76996
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.20276
|
|
CCNB2
|
cyclin B2
|
-4.64042
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-4.20825
|
|
PLK1
|
polo-like kinase 1
|
-3.89407
|
|
LDHD
|
lactate dehydrogenase D
|
-3.32399
|
|
ANKRD10
|
ankyrin repeat domain 10
|
-3.2918
|
|
MAP7
|
microtubule-associated protein 7
|
-3.1749
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.04181
|
|
PSME2
|
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
|
-2.99052
|
|
TCTN1
|
tectonic family member 1
|
-2.9747
|
|
CCNB1
|
cyclin B1
|
-2.74637
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.74566
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-2.63657
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.43648
|
|
ZNF134
|
zinc finger protein 134
|
-2.4145
|
|
GDPD5
|
glycerophosphodiester phosphodiesterase domain containing 5
|
-2.34235
|
|
TNNT1
|
troponin T type 1 (skeletal, slow)
|
-2.13709
|
|
ZNF211
|
zinc finger protein 211
|
-2.08736
|
|
MTA1
|
metastasis associated 1
|
-2.00319
|
