| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | aroclor 1260 19.2 um perturbation at 24 h in HEPG2 (Carcinogenome) |
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62 genes differentially expressed following the CRCGN013_HEPG2_24H:I02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 4.5381 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.29601 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 4.21973 |
| STIMATE | STIM activating enhancer | 4.19457 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.09468 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 4.035 |
| MAP7 | microtubule-associated protein 7 | 3.92421 |
| MAMLD1 | mastermind-like domain containing 1 | 3.87705 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 3.78734 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.73689 |
| CNPY3 | canopy FGF signaling regulator 3 | 3.36243 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 3.2717 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 3.24416 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.24357 |
| SFTPB | surfactant protein B | 3.08167 |
| INTS3 | integrator complex subunit 3 | 2.72127 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 2.66667 |
| ZNF589 | zinc finger protein 589 | 2.45973 |
| LCN2 | lipocalin 2 | 2.33533 |
| H2BC12 | H2B clustered histone 12 | 2.31959 |
| KLHL9 | kelch-like family member 9 | 2.26982 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.14023 |
| CHN1 | chimerin 1 | 2.11711 |
| THADA | thyroid adenoma associated | 2.08523 |
| GATA2 | GATA binding protein 2 | 2.07547 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.05792 |
| LRRC59 | leucine rich repeat containing 59 | 2.04249 |
| VGLL4 | vestigial-like family member 4 | 2.03716 |
| LMO7 | LIM domain 7 | 2.0257 |
| RAB20 | RAB20, member RAS oncogene family | 2.00399 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -10.0 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.7677 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.55284 |
| PCNA | proliferating cell nuclear antigen | -4.48057 |
| LAP3 | leucine aminopeptidase 3 | -4.38378 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -4.12302 |
| ADI1 | acireductone dioxygenase 1 | -4.07544 |
| GTPBP8 | GTP-binding protein 8 (putative) | -4.06648 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -4.02258 |
| GDF15 | growth differentiation factor 15 | -3.83404 |
| VAT1 | vesicle amine transport 1 | -3.58321 |
| LDHD | lactate dehydrogenase D | -3.01914 |
| TXNDC9 | thioredoxin domain containing 9 | -2.99457 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -2.95208 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.94926 |
| TBCB | tubulin folding cofactor B | -2.8672 |
| TRIB3 | tribbles pseudokinase 3 | -2.83946 |
| GNAS | GNAS complex locus | -2.8 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.61417 |
| FGFR4 | fibroblast growth factor receptor 4 | -2.58875 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -2.45992 |
| SMAGP | small cell adhesion glycoprotein | -2.43957 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.41746 |
| GRB7 | growth factor receptor-bound protein 7 | -2.34549 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.25737 |
| TMEM97 | transmembrane protein 97 | -2.23444 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.2101 |
| CNPY4 | canopy FGF signaling regulator 4 | -2.09403 |
| TUBA3C | tubulin, alpha 3c | -2.05689 |
| VPS9D1 | VPS9 domain containing 1 | -2.03221 |
| COXFA4 | cytochrome c oxidase associated subunit FA4 | -2.00767 |
| PSENEN | presenilin enhancer gamma secretase subunit | -2.00406 |