CRCGN013_HEPG2_24H:I03 Gene Set
Genes
42 genes differentially expressed following the CRCGN013_HEPG2_24H:I03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
6.99773
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
6.39072
|
|
EPHB2
|
EPH receptor B2
|
5.28356
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
5.1889
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.86714
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.86081
|
|
CBR1
|
carbonyl reductase 1
|
4.65329
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.64316
|
|
LCN2
|
lipocalin 2
|
3.5311
|
|
DNMT3A
|
DNA (cytosine-5-)-methyltransferase 3 alpha
|
3.21651
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.95816
|
|
CHN1
|
chimerin 1
|
2.91003
|
|
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3
|
2.70276
|
|
TBP
|
TATA box binding protein
|
2.5956
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
2.49618
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.32095
|
|
SLC27A3
|
solute carrier family 27 (fatty acid transporter), member 3
|
2.30742
|
|
PTK2
|
protein tyrosine kinase 2
|
2.15284
|
|
NANOS2
|
nanos homolog 2 (Drosophila)
|
2.14
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.05156
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
2.03944
|
|
MYLK
|
myosin light chain kinase
|
2.03896
|
|
ECHDC1
|
ethylmalonyl-CoA decarboxylase 1
|
2.01813
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-6.5672
|
|
ZNF586
|
zinc finger protein 586
|
-4.97674
|
|
TRIB3
|
tribbles pseudokinase 3
|
-4.94843
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-4.41464
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.33715
|
|
CCNB1
|
cyclin B1
|
-3.75613
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.53348
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-3.50316
|
|
EGF
|
epidermal growth factor
|
-3.45681
|
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding
|
-3.208
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.20223
|
|
MTA1
|
metastasis associated 1
|
-2.94051
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.77182
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.74682
|
|
NPC1
|
Niemann-Pick disease, type C1
|
-2.25093
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-2.17752
|
|
TCERG1
|
transcription elongation regulator 1
|
-2.10187
|
|
EFHD1
|
EF-hand domain family, member D1
|
-2.06469
|
|
SCRN3
|
secernin 3
|
-2.03302
|
