CRCGN013_HEPG2_24H:I05 Gene Set
Genes
44 genes differentially expressed following the CRCGN013_HEPG2_24H:I05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
5.90598
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
5.41658
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.06631
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.35463
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
4.23013
|
|
UBQLN2
|
ubiquilin 2
|
4.13177
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.45713
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
3.34058
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
3.3077
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
3.12751
|
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
2.99168
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.69499
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.60083
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
2.52815
|
|
TBP
|
TATA box binding protein
|
2.4772
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.39159
|
|
PRR15L
|
proline rich 15-like
|
2.18961
|
|
CD40
|
CD40 molecule, TNF receptor superfamily member 5
|
2.13066
|
|
HCK
|
HCK proto-oncogene, Src family tyrosine kinase
|
2.08666
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.05738
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CD320
|
CD320 molecule
|
-5.54125
|
|
VAT1
|
vesicle amine transport 1
|
-5.50727
|
|
GOLT1B
|
golgi transport 1B
|
-4.89605
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.6852
|
|
CDC20
|
cell division cycle 20
|
-4.66275
|
|
DSG2
|
desmoglein 2
|
-3.96503
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-3.85427
|
|
SCAND1
|
SCAN domain containing 1
|
-3.83116
|
|
EGF
|
epidermal growth factor
|
-3.76109
|
|
GDF15
|
growth differentiation factor 15
|
-3.45305
|
|
PEG10
|
paternally expressed 10
|
-3.19287
|
|
CCNB1
|
cyclin B1
|
-2.99315
|
|
ABCF1
|
ATP-binding cassette, sub-family F (GCN20), member 1
|
-2.89662
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.81765
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.585
|
|
BLCAP
|
bladder cancer associated protein
|
-2.56492
|
|
CASP3
|
caspase 3, apoptosis-related cysteine peptidase
|
-2.48335
|
|
SQSTM1
|
sequestosome 1
|
-2.43893
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.43786
|
|
RNF167
|
ring finger protein 167
|
-2.37117
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-2.19647
|
|
NOC2L
|
nucleolar complex associated 2 homolog (S. cerevisiae)
|
-2.09193
|
|
R3HCC1
|
R3H domain and coiled-coil containing 1
|
-2.02681
|
|
BAG6
|
BCL2-associated athanogene 6
|
-2.0071
|
