CRCGN013_HEPG2_24H:I07 Gene Set
Genes
50 genes differentially expressed following the CRCGN013_HEPG2_24H:I07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
5.17539
|
|
UBQLN2
|
ubiquilin 2
|
5.03069
|
|
KLHL21
|
kelch-like family member 21
|
4.83896
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
4.82552
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
4.70589
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
4.58439
|
|
NOTCH1
|
notch 1
|
4.36513
|
|
MELK
|
maternal embryonic leucine zipper kinase
|
3.97833
|
|
CGRRF1
|
cell growth regulator with ring finger domain 1
|
3.97295
|
|
RAB11FIP1
|
RAB11 family interacting protein 1 (class I)
|
3.92486
|
|
LAGE3
|
L antigen family, member 3
|
3.82472
|
|
LCN2
|
lipocalin 2
|
3.60098
|
|
GATA3
|
GATA binding protein 3
|
3.19439
|
|
PRR15L
|
proline rich 15-like
|
2.99546
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.71553
|
|
MMP1
|
matrix metallopeptidase 1
|
2.59556
|
|
ECD
|
ecdysoneless homolog (Drosophila)
|
2.58471
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.55593
|
|
CXCL3
|
chemokine (C-X-C motif) ligand 3
|
2.42072
|
|
TBP
|
TATA box binding protein
|
2.32969
|
|
RAI1
|
retinoic acid induced 1
|
2.30333
|
|
CYCS
|
cytochrome c, somatic
|
2.20279
|
|
MRPL17
|
mitochondrial ribosomal protein L17
|
2.17229
|
|
TRIB3
|
tribbles pseudokinase 3
|
2.1139
|
|
STK10
|
serine/threonine kinase 10
|
2.10373
|
|
EGR3
|
early growth response 3
|
2.03909
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
GNAS
|
GNAS complex locus
|
-7.49352
|
|
LDHD
|
lactate dehydrogenase D
|
-5.02044
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.88831
|
|
CCNB1
|
cyclin B1
|
-4.85012
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-4.71362
|
|
PLK1
|
polo-like kinase 1
|
-3.91818
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-3.69928
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.59185
|
|
NUP93
|
nucleoporin 93kDa
|
-3.47984
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.41902
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.40122
|
|
SNX11
|
sorting nexin 11
|
-2.39842
|
|
CCNB2
|
cyclin B2
|
-2.35883
|
|
TRPM4
|
transient receptor potential cation channel, subfamily M, member 4
|
-2.35638
|
|
SYTL2
|
synaptotagmin-like 2
|
-2.3485
|
|
NXPH3
|
neurexophilin 3
|
-2.25488
|
|
STAP1
|
signal transducing adaptor family member 1
|
-2.17482
|
|
ZNF821
|
zinc finger protein 821
|
-2.16616
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.12983
|
|
PARP8
|
poly (ADP-ribose) polymerase family, member 8
|
-2.0941
|
|
ACR
|
acrosin
|
-2.07261
|
|
KRT36
|
keratin 36, type I
|
-2.06901
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.01169
|
|
COLQ
|
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
|
-2.00082
|
