| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 3-nitropropanoic acid 2.73 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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56 genes differentially expressed following the CRCGN013_HEPG2_24H:I10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ANO1 | anoctamin 1, calcium activated chloride channel | 5.37364 |
| TATDN2 | TatD DNase domain containing 2 | 4.31061 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 4.06339 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.8822 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.60908 |
| VGLL4 | vestigial-like family member 4 | 3.54145 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.53006 |
| CCL2 | chemokine (C-C motif) ligand 2 | 3.46091 |
| ATP11B | ATPase, class VI, type 11B | 3.27761 |
| DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 | 3.26593 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 3.13202 |
| LAGE3 | L antigen family, member 3 | 2.99402 |
| AMDHD2 | amidohydrolase domain containing 2 | 2.90244 |
| MYLK | myosin light chain kinase | 2.71637 |
| WASF3 | WAS protein family, member 3 | 2.61447 |
| NANOS3 | nanos homolog 3 (Drosophila) | 2.60354 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.53921 |
| LCN2 | lipocalin 2 | 2.51044 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.37156 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.34942 |
| GPATCH8 | G patch domain containing 8 | 2.34091 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 2.25628 |
| HDAC5 | histone deacetylase 5 | 2.20686 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | 2.14016 |
| MMP17 | matrix metallopeptidase 17 (membrane-inserted) | 2.13896 |
| ROPN1B | rhophilin associated tail protein 1B | 2.10366 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.10214 |
| CYCS | cytochrome c, somatic | 2.03876 |
| CCNF | cyclin F | 2.03554 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -10.0 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -7.56734 |
| CCNB2 | cyclin B2 | -7.3397 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -5.4408 |
| PCNA | proliferating cell nuclear antigen | -4.52023 |
| CCDC86 | coiled-coil domain containing 86 | -4.28231 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -4.25896 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.12814 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.89601 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.07512 |
| ADI1 | acireductone dioxygenase 1 | -3.05928 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.04334 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -2.96706 |
| TXNDC9 | thioredoxin domain containing 9 | -2.85032 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -2.8364 |
| COG2 | component of oligomeric golgi complex 2 | -2.70599 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.67402 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -2.53329 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.53307 |
| RPF1 | ribosome production factor 1 homolog (S. cerevisiae) | -2.46432 |
| UBE3C | ubiquitin protein ligase E3C | -2.40647 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | -2.28473 |
| HAT1 | histone acetyltransferase 1 | -2.25343 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -2.18617 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.15401 |
| RNF167 | ring finger protein 167 | -2.06356 |
| KYAT3 | kynurenine aminotransferase 3 | -2.00195 |
