CRCGN013_HEPG2_24H:I11 Gene Set
Genes
53 genes differentially expressed following the CRCGN013_HEPG2_24H:I11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
7.12097
|
|
ADAT1
|
adenosine deaminase, tRNA-specific 1
|
4.14227
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.04749
|
|
NOTCH1
|
notch 1
|
3.78736
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
3.77706
|
|
CHN1
|
chimerin 1
|
3.35488
|
|
CCNA1
|
cyclin A1
|
3.14436
|
|
JADE2
|
jade family PHD finger 2
|
3.13153
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
2.9705
|
|
RFNG
|
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
2.8989
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.84073
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.78293
|
|
UBQLN2
|
ubiquilin 2
|
2.78209
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.69867
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.58558
|
|
RAB11FIP1
|
RAB11 family interacting protein 1 (class I)
|
2.51679
|
|
CRTAP
|
cartilage associated protein
|
2.49271
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.38756
|
|
EAPP
|
E2F-associated phosphoprotein
|
2.33419
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
2.27738
|
|
RFC5
|
replication factor C (activator 1) 5, 36.5kDa
|
2.27581
|
|
EVL
|
Enah/Vasp-like
|
2.10767
|
|
SMIM40
|
small integral membrane protein 40
|
2.09133
|
|
BAX
|
BCL2-associated X protein
|
2.08444
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.00262
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.43948
|
|
ACOT9
|
acyl-CoA thioesterase 9
|
-4.07376
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.00093
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.97126
|
|
BLCAP
|
bladder cancer associated protein
|
-3.74059
|
|
GOLT1B
|
golgi transport 1B
|
-3.32873
|
|
MVP
|
major vault protein
|
-3.28243
|
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
-3.22578
|
|
LDHD
|
lactate dehydrogenase D
|
-3.17828
|
|
TUBB6
|
tubulin, beta 6 class V
|
-3.10217
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.0322
|
|
HEATR1
|
HEAT repeat containing 1
|
-2.85249
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.73868
|
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding
|
-2.6303
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.58051
|
|
ABCF1
|
ATP-binding cassette, sub-family F (GCN20), member 1
|
-2.57657
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.55586
|
|
RYR1
|
ryanodine receptor 1 (skeletal)
|
-2.49034
|
|
COG7
|
component of oligomeric golgi complex 7
|
-2.4643
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.36805
|
|
MAP7
|
microtubule-associated protein 7
|
-2.35322
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.3156
|
|
STAT1
|
signal transducer and activator of transcription 1, 91kDa
|
-2.26517
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.21398
|
|
CHST1
|
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
|
-2.12595
|
|
FOCAD
|
focadhesin
|
-2.06792
|
|
MYL1
|
myosin, light chain 1, alkali; skeletal, fast
|
-2.01606
|
|
MYH8
|
myosin, heavy chain 8, skeletal muscle, perinatal
|
-2.01456
|
