CRCGN013_HEPG2_24H:I12 Gene Set
Genes
30 genes differentially expressed following the CRCGN013_HEPG2_24H:I12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LCN2
|
lipocalin 2
|
6.86261
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
4.77544
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.63908
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.45191
|
|
ETS1
|
v-ets avian erythroblastosis virus E26 oncogene homolog 1
|
3.47337
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
2.86429
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.84941
|
|
CHN1
|
chimerin 1
|
2.69502
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.68535
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.45792
|
|
CCNF
|
cyclin F
|
2.24292
|
|
INSIG1
|
insulin induced gene 1
|
2.21864
|
|
MMP1
|
matrix metallopeptidase 1
|
2.14375
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
2.09588
|
|
KIFBP
|
kinesin family binding protein
|
2.07278
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
SLC5A6
|
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
|
-4.81227
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-3.80339
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.65765
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.35323
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-3.16873
|
|
TOR1A
|
torsin family 1, member A (torsin A)
|
-2.89218
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.82087
|
|
TCTN1
|
tectonic family member 1
|
-2.67292
|
|
FASTKD5
|
FAST kinase domains 5
|
-2.66244
|
|
CAB39
|
calcium binding protein 39
|
-2.49199
|
|
GDPD5
|
glycerophosphodiester phosphodiesterase domain containing 5
|
-2.42391
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.39953
|
|
HEATR1
|
HEAT repeat containing 1
|
-2.24538
|
|
BLCAP
|
bladder cancer associated protein
|
-2.0919
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.06704
|
