CRCGN013_HEPG2_24H:I14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1,4-dimethyl-5h-pyrido[4,3-b]indol-3-amine acetate 10.32 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

909 genes differentially expressed following the CRCGN013_HEPG2_24H:I14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CDPF1 cysteine-rich, DPF motif domain containing 1 10.0
INPP1 inositol polyphosphate-1-phosphatase 10.0
LRP10 low density lipoprotein receptor-related protein 10 8.83383
BLCAP bladder cancer associated protein 7.63034
ANKRD10 ankyrin repeat domain 10 7.40701
EGR1 early growth response 1 7.16413
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 7.13888
IER3 immediate early response 3 6.968
TUBB6 tubulin, beta 6 class V 6.74051
RBM15B RNA binding motif protein 15B 6.70312
EDN1 endothelin 1 6.68459
LCN2 lipocalin 2 6.67602
DDB2 damage-specific DNA binding protein 2, 48kDa 6.53681
IGFBP3 insulin-like growth factor binding protein 3 6.53454
H2BC21 H2B clustered histone 21 6.49026
NOTCH1 notch 1 6.45737
LSR lipolysis stimulated lipoprotein receptor 6.41016
MICALL1 MICAL-like 1 6.18154
TIMP2 TIMP metallopeptidase inhibitor 2 6.08641
DYNLT3 dynein, light chain, Tctex-type 3 5.94132
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 5.85999
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 5.77215
FOSL1 FOS-like antigen 1 5.7716
MSRA methionine sulfoxide reductase A 5.61316
ABHD4 abhydrolase domain containing 4 5.48887
CTSL cathepsin L 5.47144
CAB39 calcium binding protein 39 5.43575
HSPB1 heat shock 27kDa protein 1 5.33529
NPDC1 neural proliferation, differentiation and control, 1 5.24114
ACOT9 acyl-CoA thioesterase 9 5.23976
CEMIP2 cell migration inducing hyaluronidase 2 5.09003
TOMM34 translocase of outer mitochondrial membrane 34 5.07517
CCDC92 coiled-coil domain containing 92 5.07504
ADGRG1 adhesion G protein-coupled receptor G1 5.01146
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 4.95469
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 4.92523
FAT1 FAT atypical cadherin 1 4.9201
PLA2G15 phospholipase A2, group XV 4.91816
MCOLN1 mucolipin 1 4.90807
ASCC3 activating signal cointegrator 1 complex subunit 3 4.70368
DUSP6 dual specificity phosphatase 6 4.5161
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 4.399
KHDC4 KH domain containing 4, pre-mRNA splicing factor 4.39874
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 4.32755
ADO 2-aminoethanethiol (cysteamine) dioxygenase 4.26871
TXNRD1 thioredoxin reductase 1 4.23364
SPTAN1 spectrin, alpha, non-erythrocytic 1 4.20855
GRB10 growth factor receptor-bound protein 10 4.20346
ECD ecdysoneless homolog (Drosophila) 4.20055
PRKCQ protein kinase C, theta 4.1904
BECN1 beclin 1, autophagy related 4.19
SQSTM1 sequestosome 1 4.14174
MAP7D1 MAP7 domain containing 1 4.10028
PRKCD protein kinase C, delta 4.01033
ANO1 anoctamin 1, calcium activated chloride channel 3.92407
TIGAR TP53 induced glycolysis regulatory phosphatase 3.91771
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.90473
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 3.79634
MOSPD1 motile sperm domain containing 1 3.78444
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 3.77665
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 3.72533
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 3.70797
IL4R interleukin 4 receptor 3.70409
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 3.64352
CHN1 chimerin 1 3.63704
ZMAT3 zinc finger, matrin-type 3 3.62893
TRIB1 tribbles pseudokinase 1 3.6201
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 3.56653
LYRM1 LYR motif containing 1 3.55238
MAMLD1 mastermind-like domain containing 1 3.52764
KDM5A lysine (K)-specific demethylase 5A 3.51001
FNTA farnesyltransferase, CAAX box, alpha 3.46727
ADGRE5 adhesion G protein-coupled receptor E5 3.44192
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 3.40244
TBP TATA box binding protein 3.39265
TEX10 testis expressed 10 3.34983
CBR3 carbonyl reductase 3 3.29875
GPC1 glypican 1 3.2915
GRN granulin 3.28824
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 3.26447
SLC35F2 solute carrier family 35, member F2 3.25869
SERINC1 serine incorporator 1 3.23563
HABP4 hyaluronan binding protein 4 3.2263
SKAP1 src kinase associated phosphoprotein 1 3.21593
XPC xeroderma pigmentosum, complementation group C 3.19136
RGS2 regulator of G-protein signaling 2 3.19135
GADD45A growth arrest and DNA-damage-inducible, alpha 3.14358
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 3.11748
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 3.09819
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 3.08826
RB1 retinoblastoma 1 3.07788
PTPN1 protein tyrosine phosphatase, non-receptor type 1 3.07375
GARRE1 granule associated Rac and RHOG effector 1 3.04011
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 3.03666
CAPN1 calpain 1, (mu/I) large subunit 3.02793
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 3.01008
MIDEAS mitotic deacetylase associated SANT domain protein 3.00749
BPHL biphenyl hydrolase-like (serine hydrolase) 3.00712
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 3.00574
CXCR4 chemokine (C-X-C motif) receptor 4 2.9589
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 2.94606
RBKS ribokinase 2.9244
EMC3 ER membrane protein complex subunit 3 2.91996
PLK3 polo-like kinase 3 2.91631
DUSP4 dual specificity phosphatase 4 2.9027
STXBP1 syntaxin binding protein 1 2.90061
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 2.87484
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 2.87029
PHLDA3 pleckstrin homology-like domain, family A, member 3 2.87028
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 2.86059
MRPL33 mitochondrial ribosomal protein L33 2.86044
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 2.85244
CFLAR CASP8 and FADD-like apoptosis regulator 2.85239
EPHA2 EPH receptor A2 2.84671
CCDC28A coiled-coil domain containing 28A 2.84532
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.84361
MAPK13 mitogen-activated protein kinase 13 2.83824
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.82022
DPH2 DPH2 homolog (S. cerevisiae) 2.81078
BMP4 bone morphogenetic protein 4 2.80762
SMAD3 SMAD family member 3 2.79752
HDAC7 histone deacetylase 7 2.79032
ARL8B ADP-ribosylation factor-like 8B 2.77142
YPEL5 yippee-like 5 (Drosophila) 2.76745
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 2.76039
HEG1 heart development protein with EGF-like domains 1 2.74935
UBQLN2 ubiquilin 2 2.74867
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 2.7423
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit 2.72804
KAT6A K(lysine) acetyltransferase 6A 2.71853
AOC1 amine oxidase, copper containing 1 2.70126
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 2.68393
TERF2IP telomeric repeat binding factor 2, interacting protein 2.68061
SLC26A6 solute carrier family 26 (anion exchanger), member 6 2.67595
TSC1 tuberous sclerosis 1 2.67551
H2AC19 H2A clustered histone 19 2.67173
IER5 immediate early response 5 2.66602
GIPC1 GIPC PDZ domain containing family, member 1 2.66224
BBX bobby sox homolog (Drosophila) 2.65935
EPN2 epsin 2 2.64757
STX4 syntaxin 4 2.64295
ABHD6 abhydrolase domain containing 6 2.64119
H2BC12 H2B clustered histone 12 2.64113
DOHH deoxyhypusine hydroxylase/monooxygenase 2.63062
H2AC7 H2A clustered histone 7 2.62951
ZBTB38 zinc finger and BTB domain containing 38 2.62792
CUL4B cullin 4B 2.61676
UBXN7 UBX domain protein 7 2.61614
GLRX glutaredoxin (thioltransferase) 2.61371
RPS27L ribosomal protein S27-like 2.59503
LOC127933115 uncharacterized LOC127933115 2.59404
ZNF79 zinc finger protein 79 2.58875
TM9SF3 transmembrane 9 superfamily member 3 2.58393
SOCS2 suppressor of cytokine signaling 2 2.58209
TMEM59 transmembrane protein 59 2.56759
TSPAN3 tetraspanin 3 2.56139
SESN1 sestrin 1 2.56123
CDC45 cell division cycle 45 2.55788
TIAM1 T-cell lymphoma invasion and metastasis 1 2.55594
TRIP12 thyroid hormone receptor interactor 12 2.55315
FAM168B family with sequence similarity 168, member B 2.55208
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 2.53529
GPR137B G protein-coupled receptor 137B 2.53047
DDR1 discoidin domain receptor tyrosine kinase 1 2.52312
AMIGO2 adhesion molecule with Ig-like domain 2 2.52251
SLC39A1 solute carrier family 39 (zinc transporter), member 1 2.51544
DRAM1 DNA-damage regulated autophagy modulator 1 2.5081
NUP58 nucleoporin 58 2.49641
MMP2 matrix metallopeptidase 2 2.49457
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 2.48692
SFXN3 sideroflexin 3 2.48661
TRAPPC14 trafficking protein particle complex subunit 14 2.47855
GADD45B growth arrest and DNA-damage-inducible, beta 2.47763
ADAM9 ADAM metallopeptidase domain 9 2.47664
ERCC5 excision repair cross-complementation group 5 2.47211
ZBTB43 zinc finger and BTB domain containing 43 2.47088
AEN apoptosis enhancing nuclease 2.4689
ZNF148 zinc finger protein 148 2.45496
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 2.44499
ARPC5L actin related protein 2/3 complex, subunit 5-like 2.44271
ARID4B AT rich interactive domain 4B (RBP1-like) 2.43915
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 2.43872
FOS FBJ murine osteosarcoma viral oncogene homolog 2.43688
NOL8 nucleolar protein 8 2.43301
SNIP1 Smad nuclear interacting protein 1 2.42592
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 2.42021
RRAGC Ras-related GTP binding C 2.39295
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 2.39177
ZYX zyxin 2.37776
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 2.37476
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 2.36456
GNB5 guanine nucleotide binding protein (G protein), beta 5 2.3635
PI4K2A phosphatidylinositol 4-kinase type 2 alpha 2.36117
PRPF3 pre-mRNA processing factor 3 2.35243
GHR growth hormone receptor 2.34948
UBE3C ubiquitin protein ligase E3C 2.33943
H2BC9 H2B clustered histone 9 2.33451
ERCC3 excision repair cross-complementation group 3 2.3345
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 2.31148
CDC50A cell division cycle 50 P4-ATPase accessory subunit A 2.31015
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 2.31013
RAB8B RAB8B, member RAS oncogene family 2.30456
PORCN porcupine homolog (Drosophila) 2.30129
IER2 immediate early response 2 2.29331
PPIG peptidylprolyl isomerase G (cyclophilin G) 2.29198
DOLK dolichol kinase 2.28948
CD9 CD9 molecule 2.28938
RFX5 regulatory factor X, 5 (influences HLA class II expression) 2.28557
TBPL1 TBP-like 1 2.28408
NT5E 5'-nucleotidase, ecto (CD73) 2.28276
PHLDA2 pleckstrin homology-like domain, family A, member 2 2.28021
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 2.27962
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 2.27885
SCPEP1 serine carboxypeptidase 1 2.27832
ADAM17 ADAM metallopeptidase domain 17 2.27694
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 2.27346
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 2.27299
NSUN3 NOP2/Sun domain family, member 3 2.27232
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 2.27169
NPTN neuroplastin 2.27161
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma 2.26611
GPR87 G protein-coupled receptor 87 2.25998
BPNT2 3'(2'), 5'-bisphosphate nucleotidase 2 2.25347
FAM32A family with sequence similarity 32, member A 2.24884
REC8 REC8 meiotic recombination protein 2.24797
EPAS1 endothelial PAS domain protein 1 2.23942
TOR1A torsin family 1, member A (torsin A) 2.23351
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa 2.22804
UBE2H ubiquitin-conjugating enzyme E2H 2.2276
MACF1 microtubule-actin crosslinking factor 1 2.22257
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 2.21994
DUSP3 dual specificity phosphatase 3 2.21715
IGF2R insulin-like growth factor 2 receptor 2.21703
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) 2.21681
ZMIZ1 zinc finger, MIZ-type containing 1 2.21494
FILIP1L filamin A interacting protein 1-like 2.21466
RNF111 ring finger protein 111 2.21402
MTCH1 mitochondrial carrier 1 2.21158
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 2.21104
PTTG1IP pituitary tumor-transforming 1 interacting protein 2.21087
RGL2 ral guanine nucleotide dissociation stimulator-like 2 2.20522
KLHL21 kelch-like family member 21 2.1996
TOE1 target of EGR1, member 1 (nuclear) 2.19703
RAP2A RAP2A, member of RAS oncogene family 2.19583
DSG2 desmoglein 2 2.19579
OPTN optineurin 2.19348
SYF2 SYF2 pre-mRNA-splicing factor 2.19239
DPP8 dipeptidyl-peptidase 8 2.18767
IP6K2 inositol hexakisphosphate kinase 2 2.18683
QSOX1 quiescin Q6 sulfhydryl oxidase 1 2.18543
TSKU tsukushi, small leucine rich proteoglycan 2.18102
HPSE heparanase 2.17739
PTPN14 protein tyrosine phosphatase, non-receptor type 14 2.17275
DGKA diacylglycerol kinase, alpha 80kDa 2.16726
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 2.16663
KIFC3 kinesin family member C3 2.16572
KBTBD2 kelch repeat and BTB (POZ) domain containing 2 2.16513
EGFR epidermal growth factor receptor 2.15948
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 2.15734
COQ10B coenzyme Q10 homolog B (S. cerevisiae) 2.15382
FBXL12 F-box and leucine-rich repeat protein 12 2.152
TRIM32 tripartite motif containing 32 2.15198
PTPRG protein tyrosine phosphatase, receptor type, G 2.14249
BICD2 bicaudal D homolog 2 (Drosophila) 2.1424
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 2.14091
PHF1 PHD finger protein 1 2.13529
GSAP gamma-secretase activating protein 2.13393
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 2.13156
TMEM115 transmembrane protein 115 2.12601
ELF4 E74-like factor 4 (ets domain transcription factor) 2.12137
PEA15 phosphoprotein enriched in astrocytes 15 2.11995
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 2.11052
STX3 syntaxin 3 2.10798
HOXB2 homeobox B2 2.10786
RTN4 reticulon 4 2.10686
LAMP1 lysosomal-associated membrane protein 1 2.10513
UTP11 UTP11 small subunit processome component 2.10425
OSTM1 osteopetrosis associated transmembrane protein 1 2.10282
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 2.10265
HBEGF heparin-binding EGF-like growth factor 2.10166
TMSB10 thymosin beta 10 2.10134
WWC3 WWC family member 3 2.0994
HLA-A major histocompatibility complex, class I, A 2.09859
KRT23 keratin 23, type I 2.0954
ACSL5 acyl-CoA synthetase long-chain family member 5 2.08601
TRAPPC10 trafficking protein particle complex 10 2.08476
SGSH N-sulfoglucosamine sulfohydrolase 2.08475
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 2.08318
ATF3 activating transcription factor 3 2.08159
ZFP36 ZFP36 ring finger protein 2.07645
MUC1 mucin 1, cell surface associated 2.07486
STBD1 starch binding domain 1 2.07422
PPP1R26 protein phosphatase 1, regulatory subunit 26 2.07066
DUSP2 dual specificity phosphatase 2 2.07047
JADE2 jade family PHD finger 2 2.06956
OSBPL2 oxysterol binding protein-like 2 2.06663
TWF2 twinfilin actin binding protein 2 2.06011
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) 2.05928
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1 2.05725
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 2.05535
ATF6 activating transcription factor 6 2.05417
ANAPC2 anaphase promoting complex subunit 2 2.05386
SDC4 syndecan 4 2.05295
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 2.05274
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) 2.05186
HOXD11 homeobox D11 2.05114
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 2.0493
PXDC1 PX domain containing 1 2.04691
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.04178
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1 2.03655
TRAM2 translocation associated membrane protein 2 2.03497
MAP3K2 mitogen-activated protein kinase kinase kinase 2 2.03318
EHD4 EH-domain containing 4 2.03078
TOR4A torsin family 4, member A 2.02923
PPY pancreatic polypeptide 2.02876
MAP3K14 mitogen-activated protein kinase kinase kinase 14 2.02172
RAB11FIP1 RAB11 family interacting protein 1 (class I) 2.02142
EIF1B eukaryotic translation initiation factor 1B 2.02116
SH3GLB2 SH3-domain GRB2-like endophilin B2 2.01273
TGOLN2 trans-golgi network protein 2 2.01236
ABI2 abl-interactor 2 2.01088
MAPK8 mitogen-activated protein kinase 8 2.01042
ZMYM2 zinc finger, MYM-type 2 2.00766
BAX BCL2-associated X protein 2.00721
WHRN whirlin 2.00712

decreased expression

Symbol Name Standardized Value
PYCR1 pyrroline-5-carboxylate reductase 1 -10.0
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -9.08727
PGM1 phosphoglucomutase 1 -8.36445
AARS1 alanyl-tRNA synthetase 1 -7.99115
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -7.85427
LDHD lactate dehydrogenase D -7.83198
PARP1 poly (ADP-ribose) polymerase 1 -7.80852
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -7.61844
ALDOC aldolase C, fructose-bisphosphate -7.60981
B4GAT1 beta-1,4-glucuronyltransferase 1 -7.2255
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 -7.02271
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -6.9356
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -6.58149
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -6.58092
ZW10 zw10 kinetochore protein -6.44495
MRPL12 mitochondrial ribosomal protein L12 -6.42279
ICAM3 intercellular adhesion molecule 3 -6.28059
CHMP4B charged multivesicular body protein 4B -6.07913
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -6.06889
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -5.95658
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -5.80125
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -5.55086
TCERG1 transcription elongation regulator 1 -5.51692
FGFR4 fibroblast growth factor receptor 4 -5.46766
LAGE3 L antigen family, member 3 -5.44702
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -5.42332
DHRS7 dehydrogenase/reductase (SDR family) member 7 -5.38638
DERA deoxyribose-phosphate aldolase (putative) -5.26919
CHEK2 checkpoint kinase 2 -5.26263
PHGDH phosphoglycerate dehydrogenase -5.23199
PROS1 protein S (alpha) -5.07413
CCNA2 cyclin A2 -5.02686
C2CD5 C2 calcium-dependent domain containing 5 -4.9531
CCNB1 cyclin B1 -4.94428
PECR peroxisomal trans-2-enoyl-CoA reductase -4.92818
TRAP1 TNF receptor-associated protein 1 -4.85903
EPRS1 glutamyl-prolyl-tRNA synthetase 1 -4.76044
TCTN1 tectonic family member 1 -4.72168
PHKB phosphorylase kinase, beta -4.68492
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -4.65303
TSPAN4 tetraspanin 4 -4.63295
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -4.61843
COG7 component of oligomeric golgi complex 7 -4.61805
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase -4.56796
C5 complement component 5 -4.56348
LBR lamin B receptor -4.55851
PXMP2 peroxisomal membrane protein 2, 22kDa -4.51624
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -4.46325
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -4.41956
STMN1 stathmin 1 -4.41422
PCCB propionyl CoA carboxylase, beta polypeptide -4.41318
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -4.39592
TRIB3 tribbles pseudokinase 3 -4.38476
CHEK1 checkpoint kinase 1 -4.35177
CHI3L2 chitinase 3-like 2 -4.34304
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) -4.30576
MELK maternal embryonic leucine zipper kinase -4.28155
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -4.27701
CHMP6 charged multivesicular body protein 6 -4.25201
PLK1 polo-like kinase 1 -4.2017
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -4.1813
TIMELESS timeless circadian clock -4.15445
RHOT1 ras homolog family member T1 -4.13059
MRPS16 mitochondrial ribosomal protein S16 -4.10381
ALG6 ALG6, alpha-1,3-glucosyltransferase -4.03581
ANO10 anoctamin 10 -3.93118
ZNF274 zinc finger protein 274 -3.90497
SKIC2 SKI2 subunit of superkiller complex -3.89728
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -3.84886
CENPX centromere protein X -3.82801
GCAT glycine C-acetyltransferase -3.81472
PCDHB11 protocadherin beta 11 -3.78757
AURKB aurora kinase B -3.76019
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -3.75803
XPOT exportin, tRNA -3.73928
SCCPDH saccharopine dehydrogenase (putative) -3.70157
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.68457
ASNS asparagine synthetase (glutamine-hydrolyzing) -3.67986
DCK deoxycytidine kinase -3.66214
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 -3.63783
GNG3 guanine nucleotide binding protein (G protein), gamma 3 -3.61122
NT5DC2 5'-nucleotidase domain containing 2 -3.5991
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.59414
OIP5 Opa interacting protein 5 -3.57359
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -3.55632
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -3.52134
EMC9 ER membrane protein complex subunit 9 -3.51967
RPS5 ribosomal protein S5 -3.49607
LYPLA1 lysophospholipase I -3.49559
TLCD3A TLC domain containing 3A -3.48588
NME4 NME/NM23 nucleoside diphosphate kinase 4 -3.47495
NIPSNAP1 nipsnap homolog 1 (C. elegans) -3.46928
KPTN kaptin (actin binding protein) -3.45913
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase -3.45155
SLC35B1 solute carrier family 35, member B1 -3.42747
AZGP1 alpha-2-glycoprotein 1, zinc-binding -3.42028
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -3.41258
ISOC1 isochorismatase domain containing 1 -3.40819
CCDC86 coiled-coil domain containing 86 -3.40318
CDC20 cell division cycle 20 -3.35768
RPS4Y1 ribosomal protein S4, Y-linked 1 -3.34884
PRUNE1 prune exopolyphosphatase 1 -3.31459
RFC2 replication factor C (activator 1) 2, 40kDa -3.29505
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 -3.28217
ZNF586 zinc finger protein 586 -3.27049
ECEL1 endothelin converting enzyme-like 1 -3.26622
ZDHHC4 zinc finger, DHHC-type containing 4 -3.26462
EGF epidermal growth factor -3.24274
FAM114A1 family with sequence similarity 114, member A1 -3.23969
PRCP prolylcarboxypeptidase (angiotensinase C) -3.23126
FN3KRP fructosamine 3 kinase related protein -3.21777
COQ3 coenzyme Q3 methyltransferase -3.21567
PLP1 proteolipid protein 1 -3.21242
TATDN2 TatD DNase domain containing 2 -3.21169
PIGN phosphatidylinositol glycan anchor biosynthesis, class N -3.21002
FBXO31 F-box protein 31 -3.20514
MYL9 myosin, light chain 9, regulatory -3.205
PAGR1 PAXIP1 associated glutamate-rich protein 1 -3.19526
PGAM4 phosphoglycerate mutase family member 4 -3.19437
SNX10 sorting nexin 10 -3.19322
TEDC2 tubulin epsilon and delta complex 2 -3.17799
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 -3.16253
KLHL26 kelch-like family member 26 -3.156
TMEM267 transmembrane protein 267 -3.14647
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) -3.13578
PYGL phosphorylase, glycogen, liver -3.13186
R3HDM2 R3H domain containing 2 -3.13182
DTYMK deoxythymidylate kinase (thymidylate kinase) -3.11671
MTREX Mtr4 exosome RNA helicase -3.11527
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -3.11235
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -3.10019
TOP2A topoisomerase (DNA) II alpha 170kDa -3.09535
DARS2 aspartyl-tRNA synthetase 2, mitochondrial -3.09041
SKA1 spindle and kinetochore associated complex subunit 1 -3.08571
VKORC1 vitamin K epoxide reductase complex, subunit 1 -3.06794
POLR2G polymerase (RNA) II (DNA directed) polypeptide G -3.06727
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites -3.0534
ICMT isoprenylcysteine carboxyl methyltransferase -3.04951
DENND2D DENN/MADD domain containing 2D -3.0441
HBQ1 hemoglobin, theta 1 -3.03964
PARD6A par-6 family cell polarity regulator alpha -3.03698
HMGA2 high mobility group AT-hook 2 -3.03544
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -3.0179
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -3.01048
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 -2.98967
TRAPPC3 trafficking protein particle complex 3 -2.97051
GPS1 G protein pathway suppressor 1 -2.96691
BZW2 basic leucine zipper and W2 domains 2 -2.96396
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -2.96385
ANXA7 annexin A7 -2.95403
HMBS hydroxymethylbilane synthase -2.95169
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 -2.94941
ERBB3 erb-b2 receptor tyrosine kinase 3 -2.93463
SIRT5 sirtuin 5 -2.93419
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -2.92986
CDK1 cyclin-dependent kinase 1 -2.92605
SLCO1C1 solute carrier organic anion transporter family, member 1C1 -2.92594
NENF neudesin neurotrophic factor -2.92458
ZNF280A zinc finger protein 280A -2.92265
GAA glucosidase, alpha; acid -2.91803
DTWD1 DTW domain containing 1 -2.90887
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) -2.90616
EMID1 EMI domain containing 1 -2.90489
MRPL16 mitochondrial ribosomal protein L16 -2.88846
MSH6 mutS homolog 6 -2.88016
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD) -2.87559
CENPS-CORT CENPS-CORT readthrough -2.87283
CSN1S1 casein alpha s1 -2.86394
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -2.85793
VASH2 vasohibin 2 -2.85192
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -2.8445
PTGES3 prostaglandin E synthase 3 (cytosolic) -2.84172
EEF1AKMT3 EEF1A lysine methyltransferase 3 -2.83805
GALK1 galactokinase 1 -2.83021
TBC1D16 TBC1 domain family, member 16 -2.81887
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -2.8187
ERCC6L excision repair cross-complementation group 6-like -2.81791
NUBPL nucleotide binding protein-like -2.80542
FPGT fucose-1-phosphate guanylyltransferase -2.78902
TBL3 transducin (beta)-like 3 -2.78735
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.78613
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.78491
FBXO2 F-box protein 2 -2.77959
FXYD1 FXYD domain containing ion transport regulator 1 -2.77024
NHP2 NHP2 ribonucleoprotein -2.7654
GNG7 guanine nucleotide binding protein (G protein), gamma 7 -2.7647
KIAA0319 KIAA0319 -2.75789
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -2.75458
AGO1 argonaute RISC catalytic component 1 -2.75414
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -2.75358
SOAT2 sterol O-acyltransferase 2 -2.74963
SALL2 spalt-like transcription factor 2 -2.74626
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 -2.74015
RITA1 RBPJ interacting and tubulin associated 1 -2.73922
MTA1 metastasis associated 1 -2.71927
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -2.71724
PLA2G12A phospholipase A2, group XIIA -2.71456
PHKA1 phosphorylase kinase, alpha 1 (muscle) -2.7118
LOC102724560 cystathionine beta-synthase -2.70906
CCNB2 cyclin B2 -2.70541
CDO1 cysteine dioxygenase type 1 -2.69292
MARS1 methionyl-tRNA synthetase 1 -2.69212
AQP5 aquaporin 5 -2.69187
TSFM Ts translation elongation factor, mitochondrial -2.68998
COL5A3 collagen, type V, alpha 3 -2.68813
CT55 cancer/testis antigen 55 -2.68741
CZIB CXXC motif containing zinc binding protein -2.67999
GFUS GDP-L-fucose synthase -2.67022
DCXR dicarbonyl/L-xylulose reductase -2.66646
ARL2BP ADP-ribosylation factor-like 2 binding protein -2.66134
POLE polymerase (DNA directed), epsilon, catalytic subunit -2.65757
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -2.65654
MMP17 matrix metallopeptidase 17 (membrane-inserted) -2.65611
CARMIL1 capping protein regulator and myosin 1 linker 1 -2.65518
STIMATE STIM activating enhancer -2.65426
HDAC6 histone deacetylase 6 -2.64064
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) -2.64011
GFI1B growth factor independent 1B transcription repressor -2.63627
EXOSC5 exosome component 5 -2.63352
SPC25 SPC25, NDC80 kinetochore complex component -2.63337
HSPA1A heat shock 70kDa protein 1A -2.63134
NR1H4 nuclear receptor subfamily 1, group H, member 4 -2.62964
GLYAT glycine-N-acyltransferase -2.6285
WDR70 WD repeat domain 70 -2.6281
PLA2G3 phospholipase A2, group III -2.62743
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 -2.62731
NTHL1 nth endonuclease III-like 1 (E. coli) -2.62682
TMEM209 transmembrane protein 209 -2.62616
TBCD tubulin folding cofactor D -2.62495
MRS2 MRS2 magnesium transporter -2.6192
VDAC1 voltage-dependent anion channel 1 -2.60231
PHB1 prohibitin 1 -2.59949
MGP matrix Gla protein -2.58971
FAHD2A fumarylacetoacetate hydrolase domain containing 2A -2.58902
MOCS2 molybdenum cofactor synthesis 2 -2.58881
ADISSP adipose secreted signaling protein -2.58657
RNF144A ring finger protein 144A -2.58411
CPED1 cadherin-like and PC-esterase domain containing 1 -2.58379
S100B S100 calcium binding protein B -2.58253
KLHL9 kelch-like family member 9 -2.58113
MACIR macrophage immunometabolism regulator -2.58074
MTERF3 mitochondrial transcription termination factor 3 -2.5806
SOX10 SRY (sex determining region Y)-box 10 -2.57203
BTBD8 BTB (POZ) domain containing 8 -2.56786
CEP290 centrosomal protein 290kDa -2.5653
PRODH proline dehydrogenase (oxidase) 1 -2.56368
HMMR hyaluronan-mediated motility receptor (RHAMM) -2.56065
PBK PDZ binding kinase -2.55748
DSCC1 DNA replication and sister chromatid cohesion 1 -2.55589
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 -2.54518
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 -2.54404
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -2.54256
HADH hydroxyacyl-CoA dehydrogenase -2.53681
METTL1 methyltransferase like 1 -2.53573
GLRX5 glutaredoxin 5 -2.53452
THBS4 thrombospondin 4 -2.53367
RPAIN RPA interacting protein -2.52991
RABAC1 Rab acceptor 1 (prenylated) -2.52838
IFRD2 interferon-related developmental regulator 2 -2.52755
S100A1 S100 calcium binding protein A1 -2.52736
GMPPA GDP-mannose pyrophosphorylase A -2.52298
TRMT5 tRNA methyltransferase 5 -2.52168
IFT81 intraflagellar transport 81 -2.52005
RNASE4 ribonuclease, RNase A family, 4 -2.51678
PRMT3 protein arginine methyltransferase 3 -2.51404
EPHX2 epoxide hydrolase 2, cytoplasmic -2.5101
GCDH glutaryl-CoA dehydrogenase -2.50776
TARBP2 TAR (HIV-1) RNA binding protein 2 -2.50143
FBXO5 F-box protein 5 -2.49725
ANG angiogenin, ribonuclease, RNase A family, 5 -2.49719
MTMR4 myotubularin related protein 4 -2.49303
MRPL23 mitochondrial ribosomal protein L23 -2.49127
UROS uroporphyrinogen III synthase -2.48884
INHA inhibin, alpha -2.48522
ETFB electron-transfer-flavoprotein, beta polypeptide -2.48062
GPER1 G protein-coupled estrogen receptor 1 -2.47997
TSR3 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) -2.47717
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -2.47566
KANSL1 KAT8 regulatory NSL complex subunit 1 -2.47474
FZD7 frizzled class receptor 7 -2.47209
FAM114A2 family with sequence similarity 114, member A2 -2.47142
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -2.46403
PLAC1 placenta-specific 1 -2.46341
FAM200C family with sequence similarity 200 member C -2.46095
UNG uracil-DNA glycosylase -2.45932
IL12RB1 interleukin 12 receptor, beta 1 -2.45567
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 -2.45124
HLTF helicase-like transcription factor -2.4508
POLR3B polymerase (RNA) III (DNA directed) polypeptide B -2.44799
HAUS7 HAUS augmin-like complex, subunit 7 -2.44357
TNXB tenascin XB -2.44244
TMEM177 transmembrane protein 177 -2.44214
DGKH diacylglycerol kinase, eta -2.44164
PM20D1 peptidase M20 domain containing 1 -2.441
USP22 ubiquitin specific peptidase 22 -2.43977
CERS1 ceramide synthase 1 -2.43805
HTATSF1 HIV-1 Tat specific factor 1 -2.42933
BIRC5 baculoviral IAP repeat containing 5 -2.42922
PRDM11 PR domain containing 11 -2.42845
PLK4 polo-like kinase 4 -2.42652
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 -2.42307
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -2.41739
PARP2 poly (ADP-ribose) polymerase 2 -2.41658
RFC3 replication factor C (activator 1) 3, 38kDa -2.41469
CADPS2 Ca++-dependent secretion activator 2 -2.41308
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -2.40871
NUP107 nucleoporin 107kDa -2.4067
ANGPTL7 angiopoietin-like 7 -2.40608
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 -2.40026
ECM2 extracellular matrix protein 2, female organ and adipocyte specific -2.39803
PCSK1 proprotein convertase subtilisin/kexin type 1 -2.39769
HSPB2 heat shock 27kDa protein 2 -2.39718
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional) -2.39493
UXT ubiquitously-expressed, prefoldin-like chaperone -2.39399
YARS1 tyrosyl-tRNA synthetase 1 -2.38964
VCX3A variable charge, X-linked 3A -2.38361
QDPR quinoid dihydropteridine reductase -2.38356
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase -2.38248
CCDC85B coiled-coil domain containing 85B -2.37445
COX11 COX11 cytochrome c oxidase copper chaperone -2.37293
ACSBG1 acyl-CoA synthetase bubblegum family member 1 -2.36612
GMDS GDP-mannose 4,6-dehydratase -2.36589
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.36378
DLAT dihydrolipoamide S-acetyltransferase -2.36121
SCAMP5 secretory carrier membrane protein 5 -2.36094
ANAPC5 anaphase promoting complex subunit 5 -2.35965
ACOD1 aconitate decarboxylase 1 -2.3576
TSPAN13 tetraspanin 13 -2.35667
ZFYVE21 zinc finger, FYVE domain containing 21 -2.35601
KAZALD1 Kazal-type serine peptidase inhibitor domain 1 -2.3556
CYB5RL cytochrome b5 reductase-like -2.35543
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) -2.34913
SLC30A10 solute carrier family 30, member 10 -2.34489
CGREF1 cell growth regulator with EF-hand domain 1 -2.3436
CTBP1 C-terminal binding protein 1 -2.34069
PPCDC phosphopantothenoylcysteine decarboxylase -2.33377
MYO10 myosin X -2.33347
PKLR pyruvate kinase, liver and RBC -2.33275
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 -2.3312
FAAP100 FA core complex associated protein 100 -2.33034
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria -2.329
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal -2.32782
AVPR1B arginine vasopressin receptor 1B -2.31682
RANBP17 RAN binding protein 17 -2.31503
VAT1 vesicle amine transport 1 -2.31177
WRAP73 WD repeat containing, antisense to TP73 -2.31116
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2 -2.31073
KIF15 kinesin family member 15 -2.30859
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 -2.30497
XPO1 exportin 1 -2.30345
PCDHA9 protocadherin alpha 9 -2.30302
ANTKMT adenine nucleotide translocase lysine methyltransferase -2.30212
SNRPA small nuclear ribonucleoprotein polypeptide A -2.30039
AUNIP aurora kinase A and ninein interacting protein -2.30029
XYLT1 xylosyltransferase I -2.30011
CPLX2 complexin 2 -2.29153
ZFP91 ZFP91 zinc finger protein -2.28923
NCAPD3 non-SMC condensin II complex, subunit D3 -2.28239
WRAP53 WD repeat containing, antisense to TP53 -2.28138
MYO15A myosin XVA -2.27514
HNRNPCL1 heterogeneous nuclear ribonucleoprotein C-like 1 -2.27182
RGN regucalcin -2.27024
FKBP3 FK506 binding protein 3, 25kDa -2.26939
MIS18A MIS18 kinetochore protein A -2.26884
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -2.26737
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 -2.26576
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -2.26544
IGSF1 immunoglobulin superfamily, member 1 -2.26337
SARS2 seryl-tRNA synthetase 2, mitochondrial -2.26245
ZFP30 ZFP30 zinc finger protein -2.25956
TRIL TLR4 interactor with leucine-rich repeats -2.25917
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 -2.25847
BCL7C B-cell CLL/lymphoma 7C -2.25316
PGLS 6-phosphogluconolactonase -2.2496
NUDCD3 NudC domain containing 3 -2.24901
KAT8 K(lysine) acetyltransferase 8 -2.24849
SDF2L1 stromal cell-derived factor 2-like 1 -2.24837
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide -2.248
TGFB3 transforming growth factor, beta 3 -2.24767
FTO fat mass and obesity associated -2.24764
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.24737
SKIC8 SKI8 subunit of superkiller complex -2.24577
ZIC4 Zic family member 4 -2.2452
CDK7 cyclin-dependent kinase 7 -2.24388
CEP192 centrosomal protein 192kDa -2.24322
LOC124907782 dual specificity protein phosphatase 22 -2.2412
RSBN1 round spermatid basic protein 1 -2.24052
MRPS30 mitochondrial ribosomal protein S30 -2.2389
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast) -2.23816
LYRM9 LYR motif containing 9 -2.2371
PCDHGA10 protocadherin gamma subfamily A, 10 -2.23564
SDHAF3 succinate dehydrogenase complex assembly factor 3 -2.23416
CDCA3 cell division cycle associated 3 -2.23408
GYS1 glycogen synthase 1 (muscle) -2.23342
ENOSF1 enolase superfamily member 1 -2.23333
FOCAD focadhesin -2.23318
GTPBP6 GTP binding protein 6 (putative) -2.22956
ERBB2 erb-b2 receptor tyrosine kinase 2 -2.22866
CER1 cerberus 1, DAN family BMP antagonist -2.22734
SHMT1 serine hydroxymethyltransferase 1 (soluble) -2.22578
POU4F2 POU class 4 homeobox 2 -2.22202
MYO19 myosin XIX -2.22185
JRKL JRK-like -2.22068
FIBP fibroblast growth factor (acidic) intracellular binding protein -2.21946
TOM1L1 target of myb1 (chicken)-like 1 -2.21854
BCKDK branched chain ketoacid dehydrogenase kinase -2.21696
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -2.21417
KDM4D lysine (K)-specific demethylase 4D -2.21414
LIME1 Lck interacting transmembrane adaptor 1 -2.20986
C1S complement component 1, s subcomponent -2.20834
TRAK2 trafficking protein, kinesin binding 2 -2.20517
DCTPP1 dCTP pyrophosphatase 1 -2.20251
RPIA ribose 5-phosphate isomerase A -2.20134
PARPBP PARP1 binding protein -2.20032
PCDHGA3 protocadherin gamma subfamily A, 3 -2.19956
AUTS2 autism susceptibility candidate 2 -2.19677
VCAM1 vascular cell adhesion molecule 1 -2.19542
POU3F2 POU class 3 homeobox 2 -2.19541
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta -2.19497
DHFR dihydrofolate reductase -2.19135
PAIP1 poly(A) binding protein interacting protein 1 -2.19069
PYCR3 pyrroline-5-carboxylate reductase 3 -2.1876
TRIP13 thyroid hormone receptor interactor 13 -2.18755
BBS7 Bardet-Biedl syndrome 7 -2.18741
VRK2 vaccinia related kinase 2 -2.18722
ZMYM1 zinc finger, MYM-type 1 -2.1857
KIF1B kinesin family member 1B -2.184
RHD Rh blood group, D antigen -2.18375
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) -2.18155
HMGN2 high mobility group nucleosomal binding domain 2 -2.18002
IMPACT impact RWD domain protein -2.17759
IRS4 insulin receptor substrate 4 -2.17647
ULBP1 UL16 binding protein 1 -2.17456
TSPAN6 tetraspanin 6 -2.17299
NPM3 nucleophosmin/nucleoplasmin 3 -2.17267
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) -2.17127
TAGLN transgelin -2.1712
KIF18A kinesin family member 18A -2.16939
MAGOHB mago-nashi homolog B (Drosophila) -2.16889
MAPK10 mitogen-activated protein kinase 10 -2.16667
HIRIP3 HIRA interacting protein 3 -2.1666
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -2.16656
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.16521
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 -2.1638
GCFC2 GC-rich sequence DNA-binding factor 2 -2.16256
PADI2 peptidyl arginine deiminase, type II -2.15552
MDH2 malate dehydrogenase 2, NAD (mitochondrial) -2.14845
ARHGAP11A Rho GTPase activating protein 11A -2.14681
JMJD4 jumonji domain containing 4 -2.14628
DCTN4 dynactin 4 (p62) -2.14419
TEX15 testis expressed 15 -2.14253
UBE2M ubiquitin-conjugating enzyme E2M -2.1408
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 -2.13774
CAMKMT calmodulin-lysine N-methyltransferase -2.13757
DNTT DNA nucleotidylexotransferase -2.13636
CIB2 calcium and integrin binding family member 2 -2.13502
MPIG6B megakaryocyte and platelet inhibitory receptor G6b -2.13236
TMEM123 transmembrane protein 123 -2.13214
RSPH6A radial spoke head 6 homolog A (Chlamydomonas) -2.132
BRCA1 breast cancer 1, early onset -2.13033
LGI1 leucine-rich, glioma inactivated 1 -2.12828
SMCO4 single-pass membrane protein with coiled-coil domains 4 -2.12816
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 -2.12806
JARID2 jumonji, AT rich interactive domain 2 -2.12649
NLRP2B NLR family pyrin domain containing 2B -2.12642
NFIL3 nuclear factor, interleukin 3 regulated -2.12589
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 -2.12521
POLD2 polymerase (DNA directed), delta 2, accessory subunit -2.12243
ADRA2B adrenoceptor alpha 2B -2.12124
MCM10 minichromosome maintenance complex component 10 -2.11917
CSH2 chorionic somatomammotropin hormone 2 -2.11908
FCHSD2 FCH and double SH3 domains 2 -2.11867
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 -2.11822
GPR32 G protein-coupled receptor 32 -2.11673
EBF2 early B-cell factor 2 -2.11616
UBE2C ubiquitin-conjugating enzyme E2C -2.1149
ZKSCAN3 zinc finger with KRAB and SCAN domains 3 -2.1139
ACADSB acyl-CoA dehydrogenase, short/branched chain -2.11322
RPL10L ribosomal protein L10-like -2.11296
HGFAC HGF activator -2.11204
MOCOS molybdenum cofactor sulfurase -2.11159
MCTS1 malignant T cell amplified sequence 1 -2.11057
CLCN2 chloride channel, voltage-sensitive 2 -2.10959
HDLBP high density lipoprotein binding protein -2.10637
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta -2.10514
WHR1 winged helix repair factor 1 -2.10508
RETREG1 reticulophagy regulator 1 -2.10359
ARL2 ADP-ribosylation factor-like 2 -2.10199
BTN3A2 butyrophilin, subfamily 3, member A2 -2.10193
TUBB4A tubulin, beta 4A class IVa -2.10019
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae) -2.09703
HAX1 HCLS1 associated protein X-1 -2.09454
RBM14-RBM4 RBM14-RBM4 readthrough -2.09451
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae) -2.09279
PYROXD1 pyridine nucleotide-disulphide oxidoreductase domain 1 -2.09006
TMA16 translation machinery associated 16 homolog (S. cerevisiae) -2.08946
LRIG3 leucine-rich repeats and immunoglobulin-like domains 3 -2.08935
PDGFRL platelet-derived growth factor receptor-like -2.08846
NLE1 notchless homolog 1 (Drosophila) -2.08844
ZNF711 zinc finger protein 711 -2.08747
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 -2.08675
FECH ferrochelatase -2.08263
KLHDC2 kelch domain containing 2 -2.08252
COPS6 COP9 signalosome subunit 6 -2.08228
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -2.08123
PHF21A PHD finger protein 21A -2.08017
KBTBD11 kelch repeat and BTB (POZ) domain containing 11 -2.0801
TERT telomerase reverse transcriptase -2.08008
GEMIN2 gem (nuclear organelle) associated protein 2 -2.07975
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -2.0793
ATF4 activating transcription factor 4 -2.0773
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -2.07627
SAXO6 stabilizer of axonemal microtubules 6 -2.07605
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) -2.0757
GAS2 growth arrest-specific 2 -2.0754
OLFM1 olfactomedin 1 -2.07506
ATL2 atlastin GTPase 2 -2.0738
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 -2.0671
NANOS2 nanos homolog 2 (Drosophila) -2.06649
RLIG1 RNA 5'-phosphate and 3'-OH ligase 1 -2.0655
PVRIG poliovirus receptor related immunoglobulin domain containing -2.06472
APOO apolipoprotein O -2.06319
ZNF652 zinc finger protein 652 -2.06236
HBZ hemoglobin, zeta -2.06096
SYN3 synapsin III -2.06067
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -2.06038
NOL9 nucleolar protein 9 -2.05961
ZP2 zona pellucida glycoprotein 2 (sperm receptor) -2.05942
SLC68A1 solute carrier family 68 member 1 -2.0589
SSPN sarcospan -2.05847
PRPF39 pre-mRNA processing factor 39 -2.05783
XYLB xylulokinase homolog (H. influenzae) -2.05737
KRT31 keratin 31, type I -2.05704
NNT nicotinamide nucleotide transhydrogenase -2.0568
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -2.05645
TXNDC9 thioredoxin domain containing 9 -2.05565
HSPD1 heat shock 60kDa protein 1 (chaperonin) -2.05528
CDK4 cyclin-dependent kinase 4 -2.05441
COPS7A COP9 signalosome subunit 7A -2.05362
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 -2.04995
NECAB2 N-terminal EF-hand calcium binding protein 2 -2.04949
RXRG retinoid X receptor, gamma -2.04871
SYBU syntabulin (syntaxin-interacting) -2.04829
PSAT1 phosphoserine aminotransferase 1 -2.04771
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -2.04381
GNG4 guanine nucleotide binding protein (G protein), gamma 4 -2.04329
CCDC106 coiled-coil domain containing 106 -2.04128
DRG2 developmentally regulated GTP binding protein 2 -2.0411
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2 -2.04086
ELF5 E74-like factor 5 (ets domain transcription factor) -2.03856
IRX5 iroquois homeobox 5 -2.03814
LRRC31 leucine rich repeat containing 31 -2.03682
UBXN2B UBX domain protein 2B -2.0327
PKNOX2 PBX/knotted 1 homeobox 2 -2.03144
MINAR1 membrane integral NOTCH2 associated receptor 1 -2.02918
ZNF787 zinc finger protein 787 -2.02901
MINDY1 MINDY lysine 48 deubiquitinase 1 -2.02719
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) -2.02671
CLASP2 cytoplasmic linker associated protein 2 -2.02618
LDAF1 lipid droplet assembly factor 1 -2.02194
ADSL adenylosuccinate lyase -2.02156
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1 -2.02073
POLI polymerase (DNA directed) iota -2.02035
ACACA acetyl-CoA carboxylase alpha -2.01817
CHPT1 choline phosphotransferase 1 -2.01812
SHCBP1 SHC SH2-domain binding protein 1 -2.01791
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 -2.01479
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae) -2.01451
FAM204A family with sequence similarity 204, member A -2.01016
MRPL19 mitochondrial ribosomal protein L19 -2.01006
PFAS phosphoribosylformylglycinamidine synthase -2.00994
CXCL6 chemokine (C-X-C motif) ligand 6 -2.00993
UGP2 UDP-glucose pyrophosphorylase 2 -2.00846
CD248 CD248 molecule, endosialin -2.00802
DCPS decapping enzyme, scavenger -2.00661
GFPT2 glutamine-fructose-6-phosphate transaminase 2 -2.00605
CDC6 cell division cycle 6 -2.00589
RHBDL1 rhomboid, veinlet-like 1 (Drosophila) -2.00569
DUS1L dihydrouridine synthase 1-like (S. cerevisiae) -2.00537
TIA1 TIA1 cytotoxic granule-associated RNA binding protein -2.00361
EIF3B eukaryotic translation initiation factor 3, subunit B -2.00303
HDAC3 histone deacetylase 3 -2.00208
C1QBP complement component 1, q subcomponent binding protein -2.00159
ZNF587B zinc finger protein 587B -2.00047