CRCGN013_HEPG2_24H:I15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1,4-dimethyl-5h-pyrido[4,3-b]indol-3-amine acetate 5.16 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

482 genes differentially expressed following the CRCGN013_HEPG2_24H:I15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CDPF1 cysteine-rich, DPF motif domain containing 1 10.0
INPP1 inositol polyphosphate-1-phosphatase 9.52114
CNPY3 canopy FGF signaling regulator 3 8.81143
LRP10 low density lipoprotein receptor-related protein 10 8.29872
LCN2 lipocalin 2 7.52726
NR1H2 nuclear receptor subfamily 1, group H, member 2 7.21935
IER3 immediate early response 3 6.71352
TUBB6 tubulin, beta 6 class V 6.45205
CGRRF1 cell growth regulator with ring finger domain 1 6.29452
ASCC3 activating signal cointegrator 1 complex subunit 3 6.08342
DDB2 damage-specific DNA binding protein 2, 48kDa 5.99385
FOSL1 FOS-like antigen 1 5.49495
BLCAP bladder cancer associated protein 5.16164
PRKCQ protein kinase C, theta 4.96588
IGFBP3 insulin-like growth factor binding protein 3 4.85427
MICALL1 MICAL-like 1 4.84605
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 4.7951
EGR1 early growth response 1 4.78955
IL4R interleukin 4 receptor 4.60699
TOMM34 translocase of outer mitochondrial membrane 34 4.59371
ACOT9 acyl-CoA thioesterase 9 4.44829
SQSTM1 sequestosome 1 4.28919
SPTAN1 spectrin, alpha, non-erythrocytic 1 4.27863
SMAD3 SMAD family member 3 4.26993
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 4.22303
GSTZ1 glutathione S-transferase zeta 1 4.1813
TIMP2 TIMP metallopeptidase inhibitor 2 4.14931
DUSP6 dual specificity phosphatase 6 4.10519
CAB39 calcium binding protein 39 4.02972
CCDC92 coiled-coil domain containing 92 3.98857
TRIB1 tribbles pseudokinase 1 3.9484
DYNLT3 dynein, light chain, Tctex-type 3 3.8488
PNKP polynucleotide kinase 3'-phosphatase 3.80566
CTSL cathepsin L 3.78643
GPC1 glypican 1 3.78068
S100A4 S100 calcium binding protein A4 3.75183
KIFBP kinesin family binding protein 3.74097
BECN1 beclin 1, autophagy related 3.67053
RALB v-ral simian leukemia viral oncogene homolog B 3.64745
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 3.61096
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 3.59502
MAP7D1 MAP7 domain containing 1 3.52026
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 3.46539
GRB10 growth factor receptor-bound protein 10 3.45008
CFLAR CASP8 and FADD-like apoptosis regulator 3.44973
LSR lipolysis stimulated lipoprotein receptor 3.40298
ABHD6 abhydrolase domain containing 6 3.3928
GLRX glutaredoxin (thioltransferase) 3.37885
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 3.35177
ADAT1 adenosine deaminase, tRNA-specific 1 3.34564
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 3.31762
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 3.22613
MVP major vault protein 3.20109
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 3.1559
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 3.13454
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 3.10722
MAPK13 mitogen-activated protein kinase 13 3.06366
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 3.03769
ANO1 anoctamin 1, calcium activated chloride channel 3.03665
BPHL biphenyl hydrolase-like (serine hydrolase) 3.03464
EIF6 eukaryotic translation initiation factor 6 2.94464
FILIP1L filamin A interacting protein 1-like 2.94218
KHDC4 KH domain containing 4, pre-mRNA splicing factor 2.92842
FAT1 FAT atypical cadherin 1 2.89779
EPHA2 EPH receptor A2 2.89535
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.89274
RFX5 regulatory factor X, 5 (influences HLA class II expression) 2.89223
TXNRD1 thioredoxin reductase 1 2.88935
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.84686
UBE2A ubiquitin-conjugating enzyme E2A 2.83512
PHLDA3 pleckstrin homology-like domain, family A, member 3 2.75075
ADGRE5 adhesion G protein-coupled receptor E5 2.71884
DUSP3 dual specificity phosphatase 3 2.71874
UBQLN2 ubiquilin 2 2.71829
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 2.69601
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 2.68642
YIPF3 Yip1 domain family, member 3 2.66268
STXBP1 syntaxin binding protein 1 2.65959
GHITM growth hormone inducible transmembrane protein 2.63768
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 2.62924
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 2.5836
RBM15B RNA binding motif protein 15B 2.56844
PRKCD protein kinase C, delta 2.5684
PRPF3 pre-mRNA processing factor 3 2.56788
TIGAR TP53 induced glycolysis regulatory phosphatase 2.55558
MEA1 male-enhanced antigen 1 2.53326
STX1A syntaxin 1A (brain) 2.52663
S100A3 S100 calcium binding protein A3 2.5072
LOC122526780 uncharacterized LOC122526780 2.4956
BZW2 basic leucine zipper and W2 domains 2 2.48748
TGFB1I1 transforming growth factor beta 1 induced transcript 1 2.48564
TRIP12 thyroid hormone receptor interactor 12 2.48176
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 2.47364
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 2.46439
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 2.46205
TERF2IP telomeric repeat binding factor 2, interacting protein 2.46008
JADE2 jade family PHD finger 2 2.454
CEMIP2 cell migration inducing hyaluronidase 2 2.4313
NSDHL NAD(P) dependent steroid dehydrogenase-like 2.42987
PLEK2 pleckstrin 2 2.41682
SCRN1 secernin 1 2.4098
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 2.40186
ABHD4 abhydrolase domain containing 4 2.39321
MOSPD1 motile sperm domain containing 1 2.38548
ITGAV integrin, alpha V 2.37856
SOCS2 suppressor of cytokine signaling 2 2.37789
ZMYM2 zinc finger, MYM-type 2 2.3675
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) 2.36265
CDKN2A cyclin-dependent kinase inhibitor 2A 2.36084
BDH1 3-hydroxybutyrate dehydrogenase, type 1 2.35288
FPGS folylpolyglutamate synthase 2.34937
BYSL bystin-like 2.3221
COG4 component of oligomeric golgi complex 4 2.31171
ANXA3 annexin A3 2.29835
ZMAT3 zinc finger, matrin-type 3 2.27582
MEAF6 MYST/Esa1-associated factor 6 2.27304
PORCN porcupine homolog (Drosophila) 2.27256
XPC xeroderma pigmentosum, complementation group C 2.26191
GTPBP2 GTP binding protein 2 2.26108
UIMC1 ubiquitin interaction motif containing 1 2.24847
PLA2G15 phospholipase A2, group XV 2.24713
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 2.22649
PLK3 polo-like kinase 3 2.22623
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 2.21825
ELP3 elongator acetyltransferase complex subunit 3 2.20243
SNX6 sorting nexin 6 2.19993
ADO 2-aminoethanethiol (cysteamine) dioxygenase 2.19033
MCUR1 mitochondrial calcium uniporter regulator 1 2.18337
RGL2 ral guanine nucleotide dissociation stimulator-like 2 2.1819
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 2.15925
LAP3 leucine aminopeptidase 3 2.15829
EPB41L1 erythrocyte membrane protein band 4.1-like 1 2.15829
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 2.15452
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 2.14262
CCSER2 coiled-coil serine-rich protein 2 2.13938
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 2.13921
UBE2H ubiquitin-conjugating enzyme E2H 2.12858
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 2.12821
GADD45A growth arrest and DNA-damage-inducible, alpha 2.1177
CDK6 cyclin-dependent kinase 6 2.11636
FAM50A family with sequence similarity 50, member A 2.11415
CNPPD1 cyclin Pas1/PHO80 domain containing 1 2.10787
FBXO28 F-box protein 28 2.10781
H2BC21 H2B clustered histone 21 2.10399
SRSF4 serine/arginine-rich splicing factor 4 2.10126
IGFBP4 insulin-like growth factor binding protein 4 2.10035
AGAP4 ArfGAP with GTPase domain, ankyrin repeat and PH domain 4 2.09747
PLEC plectin 2.08716
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 2.08576
ANKRD10 ankyrin repeat domain 10 2.07465
TRIM32 tripartite motif containing 32 2.07435
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C 2.06966
METRN meteorin, glial cell differentiation regulator 2.06889
SOX4 SRY (sex determining region Y)-box 4 2.06599
VEGFC vascular endothelial growth factor C 2.0652
LOC128125814 uncharacterized LOC128125814 2.06025
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 2.05738
SARS1 seryl-tRNA synthetase 1 2.04999
STX18 syntaxin 18 2.04968
BCAR3 breast cancer anti-estrogen resistance 3 2.0458
CYTH2 cytohesin 2 2.04535
ELL2 elongation factor, RNA polymerase II, 2 2.0426
SCAND1 SCAN domain containing 1 2.03834
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 2.03798
WDR1 WD repeat domain 1 2.03463
WFS1 Wolfram syndrome 1 (wolframin) 2.03392
TRIP4 thyroid hormone receptor interactor 4 2.03349
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 2.0301
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis) 2.02926
ITCH itchy E3 ubiquitin protein ligase 2.0141
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 2.01171
ITPRID2 ITPR interacting domain containing 2 2.00974
GIPC1 GIPC PDZ domain containing family, member 1 2.0091
HSPB1 heat shock 27kDa protein 1 2.00856
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 2.00484

decreased expression

Symbol Name Standardized Value
FGFR4 fibroblast growth factor receptor 4 -7.7559
ALDOC aldolase C, fructose-bisphosphate -7.31294
C5 complement component 5 -6.65384
C2CD5 C2 calcium-dependent domain containing 5 -6.53429
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -6.47597
ZW10 zw10 kinetochore protein -6.46063
UBE2C ubiquitin-conjugating enzyme E2C -6.10795
PECR peroxisomal trans-2-enoyl-CoA reductase -6.09077
MELK maternal embryonic leucine zipper kinase -5.97597
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -5.96585
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -5.81924
CCNA2 cyclin A2 -5.79074
DERA deoxyribose-phosphate aldolase (putative) -5.75717
TMEM97 transmembrane protein 97 -5.45659
LBR lamin B receptor -5.37852
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -5.28913
AURKB aurora kinase B -5.28142
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -5.19302
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -5.12656
PLK1 polo-like kinase 1 -5.09975
PYCR1 pyrroline-5-carboxylate reductase 1 -5.08818
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -5.06395
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -5.05595
ISOC1 isochorismatase domain containing 1 -5.04516
PGM1 phosphoglucomutase 1 -4.9999
TOP2A topoisomerase (DNA) II alpha 170kDa -4.97412
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -4.92371
PARP1 poly (ADP-ribose) polymerase 1 -4.85416
TCTN1 tectonic family member 1 -4.83828
PROS1 protein S (alpha) -4.76109
PRCP prolylcarboxypeptidase (angiotensinase C) -4.74098
CHEK2 checkpoint kinase 2 -4.47713
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -4.47156
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -4.41047
CCNB1 cyclin B1 -4.28349
PSRC1 proline/serine-rich coiled-coil 1 -4.273
SOAT2 sterol O-acyltransferase 2 -4.15364
NUCB2 nucleobindin 2 -4.06792
FASTKD5 FAST kinase domains 5 -4.01612
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -4.01331
RGS2 regulator of G-protein signaling 2 -3.99581
BIRC5 baculoviral IAP repeat containing 5 -3.92904
CHEK1 checkpoint kinase 1 -3.84985
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -3.83376
TRAP1 TNF receptor-associated protein 1 -3.80544
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -3.75409
AMDHD2 amidohydrolase domain containing 2 -3.74919
PCNA proliferating cell nuclear antigen -3.73246
RFC2 replication factor C (activator 1) 2, 40kDa -3.62466
B4GAT1 beta-1,4-glucuronyltransferase 1 -3.57657
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -3.55399
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -3.54288
HADH hydroxyacyl-CoA dehydrogenase -3.47721
CDC20 cell division cycle 20 -3.4463
PHGDH phosphoglycerate dehydrogenase -3.4034
RPS4Y1 ribosomal protein S4, Y-linked 1 -3.34136
CDK1 cyclin-dependent kinase 1 -3.33315
PXMP2 peroxisomal membrane protein 2, 22kDa -3.31672
TOPBP1 topoisomerase (DNA) II binding protein 1 -3.24589
USP6NL USP6 N-terminal like -3.24541
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.23608
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -3.21569
FBXO31 F-box protein 31 -3.1834
SMCO4 single-pass membrane protein with coiled-coil domains 4 -3.14538
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -3.12933
FHL2 four and a half LIM domains 2 -3.12487
STMN1 stathmin 1 -3.12351
MLEC malectin -3.11922
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like -3.11549
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -3.10066
TLCD3A TLC domain containing 3A -3.06848
PIGN phosphatidylinositol glycan anchor biosynthesis, class N -3.05422
NUP85 nucleoporin 85kDa -3.05145
GTPBP8 GTP-binding protein 8 (putative) -3.03795
TCERG1 transcription elongation regulator 1 -3.01996
ADI1 acireductone dioxygenase 1 -2.97667
BLMH bleomycin hydrolase -2.96782
HSPA1A heat shock 70kDa protein 1A -2.94963
TEDC2 tubulin epsilon and delta complex 2 -2.94813
UXT ubiquitously-expressed, prefoldin-like chaperone -2.94366
VASH2 vasohibin 2 -2.90757
WDR7 WD repeat domain 7 -2.90628
GCAT glycine C-acetyltransferase -2.90503
OIP5 Opa interacting protein 5 -2.89756
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -2.87842
MCM10 minichromosome maintenance complex component 10 -2.87144
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -2.86718
ASGR1 asialoglycoprotein receptor 1 -2.83467
ADM2 adrenomedullin 2 -2.82909
KIF15 kinesin family member 15 -2.8087
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -2.80567
TIMELESS timeless circadian clock -2.79168
CHI3L2 chitinase 3-like 2 -2.78786
PTGES3 prostaglandin E synthase 3 (cytosolic) -2.78514
MRPL12 mitochondrial ribosomal protein L12 -2.77038
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.76915
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -2.75718
MMP17 matrix metallopeptidase 17 (membrane-inserted) -2.7401
DENND2D DENN/MADD domain containing 2D -2.73558
HMOX1 heme oxygenase 1 -2.73258
AVPR1B arginine vasopressin receptor 1B -2.72636
POLK polymerase (DNA directed) kappa -2.72374
PRUNE1 prune exopolyphosphatase 1 -2.71551
MSH6 mutS homolog 6 -2.71431
INCENP inner centromere protein antigens 135/155kDa -2.70297
NT5DC2 5'-nucleotidase domain containing 2 -2.69769
TMPRSS6 transmembrane protease, serine 6 -2.69646
ZNF835 zinc finger protein 835 -2.6935
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -2.69323
SLC35B1 solute carrier family 35, member B1 -2.68854
CSH2 chorionic somatomammotropin hormone 2 -2.66616
GFUS GDP-L-fucose synthase -2.65407
TCTN2 tectonic family member 2 -2.6538
SNX10 sorting nexin 10 -2.65175
TERT telomerase reverse transcriptase -2.64969
SLC30A10 solute carrier family 30, member 10 -2.63361
RHBG Rh family, B glycoprotein (gene/pseudogene) -2.63071
ETNK2 ethanolamine kinase 2 -2.60524
STIMATE STIM activating enhancer -2.59838
ICMT isoprenylcysteine carboxyl methyltransferase -2.59685
PKLR pyruvate kinase, liver and RBC -2.59601
PGRMC1 progesterone receptor membrane component 1 -2.59393
GPR27 G protein-coupled receptor 27 -2.5823
KRT85 keratin 85, type II -2.5479
GALK1 galactokinase 1 -2.54231
ALG3 ALG3, alpha-1,3- mannosyltransferase -2.53907
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 -2.52268
CDCA3 cell division cycle associated 3 -2.51738
KIF14 kinesin family member 14 -2.51141
ERCC6L excision repair cross-complementation group 6-like -2.50891
TBC1D10C TBC1 domain family, member 10C -2.48877
ZFP30 ZFP30 zinc finger protein -2.48416
PCDHGA3 protocadherin gamma subfamily A, 3 -2.47979
GBX1 gastrulation brain homeobox 1 -2.47478
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.47328
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -2.46028
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 -2.45664
ICAM3 intercellular adhesion molecule 3 -2.45594
GNRH2 gonadotropin-releasing hormone 2 -2.44267
TBC1D8B TBC1 domain family, member 8B (with GRAM domain) -2.42968
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -2.42827
ATL2 atlastin GTPase 2 -2.42124
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 -2.41465
NECAB2 N-terminal EF-hand calcium binding protein 2 -2.41376
CELA3A chymotrypsin-like elastase family, member 3A -2.41263
AZGP1 alpha-2-glycoprotein 1, zinc-binding -2.40846
POLR1A polymerase (RNA) I polypeptide A, 194kDa -2.40559
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide -2.39658
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta -2.39226
ADH6 alcohol dehydrogenase 6 (class V) -2.38993
COPZ1 coatomer protein complex, subunit zeta 1 -2.38681
PFKL phosphofructokinase, liver -2.38095
CPB2 carboxypeptidase B2 (plasma) -2.37688
CASP3 caspase 3, apoptosis-related cysteine peptidase -2.37527
LOC102723996 ICOS ligand -2.36322
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -2.36054
A1CF APOBEC1 complementation factor -2.36003
SPC25 SPC25, NDC80 kinetochore complex component -2.35513
DUT deoxyuridine triphosphatase -2.35128
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -2.35084
RLBP1 retinaldehyde binding protein 1 -2.34726
SKA1 spindle and kinetochore associated complex subunit 1 -2.34583
ZNRF4 zinc and ring finger 4 -2.34446
KHK ketohexokinase (fructokinase) -2.34353
CHMP6 charged multivesicular body protein 6 -2.3352
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -2.3289
GNAS GNAS complex locus -2.3268
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme -2.32309
VWA7 von Willebrand factor A domain containing 7 -2.31704
MYO19 myosin XIX -2.31254
ANGPT4 angiopoietin 4 -2.31252
PRDM12 PR domain containing 12 -2.30673
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 -2.30642
CDC25A cell division cycle 25A -2.30623
CTRB2 chymotrypsinogen B2 -2.30357
ARID3A AT rich interactive domain 3A (BRIGHT-like) -2.30085
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 -2.2963
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -2.28837
DCK deoxycytidine kinase -2.28774
MAT1A methionine adenosyltransferase I, alpha -2.28752
PCCB propionyl CoA carboxylase, beta polypeptide -2.287
PCDHGA10 protocadherin gamma subfamily A, 10 -2.25444
GPT glutamic-pyruvate transaminase (alanine aminotransferase) -2.25097
A4GALT alpha 1,4-galactosyltransferase -2.24327
KIF11 kinesin family member 11 -2.24248
TGFB3 transforming growth factor, beta 3 -2.24138
CHAD chondroadherin -2.23588
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -2.23261
C4BPA complement component 4 binding protein, alpha -2.22986
KIAA0319 KIAA0319 -2.22983
LIME1 Lck interacting transmembrane adaptor 1 -2.22794
PRDM11 PR domain containing 11 -2.22779
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -2.22646
BARX2 BARX homeobox 2 -2.2257
GALR3 galanin receptor 3 -2.22108
FAM117A family with sequence similarity 117, member A -2.21554
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 -2.21144
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.21009
ASF1B anti-silencing function 1B histone chaperone -2.20931
CEP192 centrosomal protein 192kDa -2.20543
CHAF1B chromatin assembly factor 1, subunit B (p60) -2.20414
TENM4 teneurin transmembrane protein 4 -2.20133
MYO10 myosin X -2.20026
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -2.19861
KIF18A kinesin family member 18A -2.1922
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 -2.19197
TUBA3E tubulin, alpha 3e -2.18947
APOH apolipoprotein H (beta-2-glycoprotein I) -2.18938
GSTCD glutathione S-transferase, C-terminal domain containing -2.18339
SDHAF1 succinate dehydrogenase complex assembly factor 1 -2.18183
ARHGAP19 Rho GTPase activating protein 19 -2.18167
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2 -2.17701
TK1 thymidine kinase 1, soluble -2.17612
KIF4A kinesin family member 4A -2.17109
MSMO1 methylsterol monooxygenase 1 -2.16986
PCDHB6 protocadherin beta 6 -2.16805
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.16789
ECH1 enoyl CoA hydratase 1, peroxisomal -2.16711
EGF epidermal growth factor -2.16404
RNF130 ring finger protein 130 -2.16303
PRAMEF13 PRAME family member 13 -2.16284
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B -2.16041
CCIN calicin -2.15795
CPNE3 copine III -2.15403
FBXO5 F-box protein 5 -2.15395
CTXND1 cortexin domain containing 1 -2.15082
FAM114A1 family with sequence similarity 114, member A1 -2.15032
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 -2.14904
COL3A1 collagen, type III, alpha 1 -2.14784
MVK mevalonate kinase -2.14582
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) -2.14502
MATCAP2 microtubule associated tyrosine carboxypeptidase 2 -2.1444
UBE3B ubiquitin protein ligase E3B -2.14266
PRELP proline/arginine-rich end leucine-rich repeat protein -2.14093
S100A1 S100 calcium binding protein A1 -2.14026
LGMN legumain -2.13934
MCMBP minichromosome maintenance complex binding protein -2.13855
OXT oxytocin/neurophysin I prepropeptide -2.13698
MYOD1 myogenic differentiation 1 -2.13568
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 -2.13418
CHRNG cholinergic receptor, nicotinic, gamma (muscle) -2.12852
CYB5RL cytochrome b5 reductase-like -2.12849
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -2.12699
KLK14 kallikrein-related peptidase 14 -2.12554
ALG6 ALG6, alpha-1,3-glucosyltransferase -2.12108
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -2.11789
MYLK myosin light chain kinase -2.11551
PAGR1 PAXIP1 associated glutamate-rich protein 1 -2.11474
PARD6A par-6 family cell polarity regulator alpha -2.11301
RPS5 ribosomal protein S5 -2.10963
UNG uracil-DNA glycosylase -2.10904
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) -2.10889
GCGR glucagon receptor -2.10813
KIF18B kinesin family member 18B -2.10428
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 -2.10396
FZD7 frizzled class receptor 7 -2.10383
PSPN persephin -2.10086
TNNT3 troponin T type 3 (skeletal, fast) -2.09716
OR10J1 olfactory receptor, family 10, subfamily J, member 1 -2.09549
SIRT3 sirtuin 3 -2.09458
CDC6 cell division cycle 6 -2.09393
SQLE squalene epoxidase -2.09344
ARHGAP11A Rho GTPase activating protein 11A -2.09247
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like -2.09218
YIPF2 Yip1 domain family, member 2 -2.09211
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma -2.09136
BICDL1 BICD family like cargo adaptor 1 -2.08882
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 -2.08389
CDO1 cysteine dioxygenase type 1 -2.08353
PKD2L1 polycystic kidney disease 2-like 1 -2.07845
DCP2 decapping mRNA 2 -2.07796
HPX hemopexin -2.07744
TXLNG taxilin gamma -2.07227
TMPRSS5 transmembrane protease, serine 5 -2.0713
DEK DEK proto-oncogene -2.06991
KLK12 kallikrein-related peptidase 12 -2.06848
ECEL1 endothelin converting enzyme-like 1 -2.06716
CENPA centromere protein A -2.06701
RPL10L ribosomal protein L10-like -2.06464
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -2.06327
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -2.06172
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) -2.0613
HS6ST1 heparan sulfate 6-O-sulfotransferase 1 -2.05942
RAD51AP1 RAD51 associated protein 1 -2.05902
TXNL4B thioredoxin-like 4B -2.0583
PCDHB13 protocadherin beta 13 -2.05386
DCN decorin -2.04859
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 -2.04498
CD320 CD320 molecule -2.04412
CRELD2 cysteine-rich with EGF-like domains 2 -2.04109
TRIP13 thyroid hormone receptor interactor 13 -2.04107
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 -2.03976
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -2.03726
TFCP2L1 transcription factor CP2-like 1 -2.03702
WDR18 WD repeat domain 18 -2.03296
PHKA1 phosphorylase kinase, alpha 1 (muscle) -2.02917
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8 -2.02762
C8A complement component 8, alpha polypeptide -2.02418
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 -2.01917
SCGB1D1 secretoglobin, family 1D, member 1 -2.0152
PYCR3 pyrroline-5-carboxylate reductase 3 -2.01471
PYROXD1 pyridine nucleotide-disulphide oxidoreductase domain 1 -2.01417
G6PC2 glucose-6-phosphatase, catalytic, 2 -2.01364
RBM14-RBM4 RBM14-RBM4 readthrough -2.01174
RNFT2 ring finger protein, transmembrane 2 -2.01096
AUNIP aurora kinase A and ninein interacting protein -2.01066
TMEM258 transmembrane protein 258 -2.00915