CRCGN013_HEPG2_24H:I18 Gene Set
Genes
36 genes differentially expressed following the CRCGN013_HEPG2_24H:I18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
5.51132
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
4.80016
|
|
PRR15L
|
proline rich 15-like
|
4.08191
|
|
LCN2
|
lipocalin 2
|
3.60881
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
3.5988
|
|
UBQLN2
|
ubiquilin 2
|
3.44546
|
|
E2F2
|
E2F transcription factor 2
|
3.16973
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
3.0923
|
|
MAP7
|
microtubule-associated protein 7
|
2.88134
|
|
HOXA10
|
homeobox A10
|
2.74513
|
|
CNPY3
|
canopy FGF signaling regulator 3
|
2.74341
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
2.66984
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.53124
|
|
DDB2
|
damage-specific DNA binding protein 2, 48kDa
|
2.42421
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.35265
|
|
CEMIP2
|
cell migration inducing hyaluronidase 2
|
2.25045
|
|
IER3
|
immediate early response 3
|
2.24929
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
2.17112
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.06098
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-5.80251
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-5.09159
|
|
GNAS
|
GNAS complex locus
|
-4.58176
|
|
SLC25A13
|
solute carrier family 25 (aspartate/glutamate carrier), member 13
|
-3.60814
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.39315
|
|
VAT1
|
vesicle amine transport 1
|
-3.15263
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.93795
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.83078
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.72638
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.59555
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-2.56822
|
|
ISOC1
|
isochorismatase domain containing 1
|
-2.40997
|
|
HMGCR
|
3-hydroxy-3-methylglutaryl-CoA reductase
|
-2.1723
|
|
PRCP
|
prolylcarboxypeptidase (angiotensinase C)
|
-2.14491
|
|
MSMO1
|
methylsterol monooxygenase 1
|
-2.07993
|
|
ZNF586
|
zinc finger protein 586
|
-2.03191
|
|
PROS1
|
protein S (alpha)
|
-2.00051
|
