CRCGN013_HEPG2_24H:I20 Gene Set
Genes
36 genes differentially expressed following the CRCGN013_HEPG2_24H:I20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
7.16748
|
|
LAGE3
|
L antigen family, member 3
|
4.72112
|
|
E2F2
|
E2F transcription factor 2
|
4.53312
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.39944
|
|
CHN1
|
chimerin 1
|
4.36609
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.45979
|
|
LOC122526780
|
uncharacterized LOC122526780
|
3.11021
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.09174
|
|
ZFP36
|
ZFP36 ring finger protein
|
3.0853
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.06386
|
|
TBP
|
TATA box binding protein
|
3.00906
|
|
BAX
|
BCL2-associated X protein
|
2.9592
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.83791
|
|
TGFBR2
|
transforming growth factor, beta receptor II (70/80kDa)
|
2.76736
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.71847
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.55638
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
2.53477
|
|
MYLK
|
myosin light chain kinase
|
2.49807
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.44537
|
|
TCFL5
|
transcription factor-like 5 (basic helix-loop-helix)
|
2.16552
|
|
CBR3
|
carbonyl reductase 3
|
2.16066
|
|
BAMBI
|
BMP and activin membrane-bound inhibitor
|
2.15779
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
2.10899
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.97281
|
|
BLCAP
|
bladder cancer associated protein
|
-6.02974
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-5.50242
|
|
INPP1
|
inositol polyphosphate-1-phosphatase
|
-4.13741
|
|
CCNB2
|
cyclin B2
|
-3.91037
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-3.22874
|
|
CCNB1
|
cyclin B1
|
-3.00496
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.9082
|
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
-2.85269
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.58779
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.51483
|
|
PSME1
|
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
|
-2.42414
|
|
RBM15B
|
RNA binding motif protein 15B
|
-2.00184
|
