CRCGN013_HEPG2_24H:I21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1h-1,2,3-benzotriazole 5.25 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

46 genes differentially expressed following the CRCGN013_HEPG2_24H:I21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 6.78988
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 6.09925
MCOLN1 mucolipin 1 5.36895
C2CD2 C2 calcium-dependent domain containing 2 5.25007
UBQLN2 ubiquilin 2 5.05913
CBR3 carbonyl reductase 3 4.93999
CARMIL1 capping protein regulator and myosin 1 linker 1 4.52473
SNAP25 synaptosomal-associated protein, 25kDa 4.20219
BAX BCL2-associated X protein 4.03916
CGRRF1 cell growth regulator with ring finger domain 1 3.55075
TIAM1 T-cell lymphoma invasion and metastasis 1 2.89123
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 2.84362
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.8261
ATP11B ATPase, class VI, type 11B 2.78943
PLSCR3 phospholipid scramblase 3 2.72812
JADE2 jade family PHD finger 2 2.72362
CRTAP cartilage associated protein 2.65655
CCNF cyclin F 2.62771
CCDC85B coiled-coil domain containing 85B 2.48144
NPM3 nucleophosmin/nucleoplasmin 3 2.38441
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.37534
H2BC12 H2B clustered histone 12 2.34212
CDC45 cell division cycle 45 2.31923
SLC39A1 solute carrier family 39 (zinc transporter), member 1 2.22327
MAST2 microtubule associated serine/threonine kinase 2 2.16359
SIRT3 sirtuin 3 2.11847
SKIC8 SKI8 subunit of superkiller complex 2.09234
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 2.07577
ZNF428 zinc finger protein 428 2.06277
STK16 serine/threonine kinase 16 2.01616

decreased expression

Symbol Name Standardized Value
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -4.65004
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -3.71313
EGF epidermal growth factor -3.55716
OXA1L oxidase (cytochrome c) assembly 1-like -3.0398
BLCAP bladder cancer associated protein -2.9537
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -2.9493
TRAP1 TNF receptor-associated protein 1 -2.74429
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 -2.73105
ZNF586 zinc finger protein 586 -2.67946
TLCD3A TLC domain containing 3A -2.63552
ANKRD10 ankyrin repeat domain 10 -2.56106
HLA-DMA major histocompatibility complex, class II, DM alpha -2.4974
ZMIZ1 zinc finger, MIZ-type containing 1 -2.20662
ILK integrin-linked kinase -2.17434
PDLIM1 PDZ and LIM domain 1 -2.16563
GRB2 growth factor receptor-bound protein 2 -2.02188