CRCGN013_HEPG2_24H:I24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1h-1,2,3-benzotriazole 0.66 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

35 genes differentially expressed following the CRCGN013_HEPG2_24H:I24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CIAO3 cytosolic iron-sulfur assembly component 3 4.89604
HLA-DMA major histocompatibility complex, class II, DM alpha 4.67138
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.52728
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like 2.92635
MCUR1 mitochondrial calcium uniporter regulator 1 2.77286
ADAM10 ADAM metallopeptidase domain 10 2.55399
PRR15L proline rich 15-like 2.44997
UFM1 ubiquitin-fold modifier 1 2.38254
BAX BCL2-associated X protein 2.31471
HLA-DRA major histocompatibility complex, class II, DR alpha 2.27776
CEMIP2 cell migration inducing hyaluronidase 2 2.15566
RBKS ribokinase 2.081
MAP7 microtubule-associated protein 7 2.01677
KCNK1 potassium channel, two pore domain subfamily K, member 1 2.01483

decreased expression

Symbol Name Standardized Value
PCNA proliferating cell nuclear antigen -8.27482
SCAND1 SCAN domain containing 1 -5.80966
CD320 CD320 molecule -4.55089
CDC20 cell division cycle 20 -4.41183
YME1L1 YME1-like 1 ATPase -4.13392
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -3.8195
FGFR4 fibroblast growth factor receptor 4 -3.81891
HMG20B high mobility group 20B -3.35448
UGDH UDP-glucose 6-dehydrogenase -3.22326
GNAS GNAS complex locus -3.16525
CRK v-crk avian sarcoma virus CT10 oncogene homolog -2.94959
GOLT1B golgi transport 1B -2.91776
CCNB2 cyclin B2 -2.64821
SLC35F2 solute carrier family 35, member F2 -2.61219
NRIP1 nuclear receptor interacting protein 1 -2.48526
OXA1L oxidase (cytochrome c) assembly 1-like -2.44966
NVL nuclear VCP-like -2.35966
MT1H metallothionein 1H -2.20536
BICRA BRD4 interacting chromatin remodeling complex associated protein -2.05794
MAGEC2 melanoma antigen family C2 -2.05509
ANKRD26 ankyrin repeat domain 26 -2.00334