CRCGN013_HEPG2_24H:J05 Gene Set
Genes
51 genes differentially expressed following the CRCGN013_HEPG2_24H:J05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LCN2
|
lipocalin 2
|
6.3278
|
|
UBQLN2
|
ubiquilin 2
|
5.10674
|
|
STK10
|
serine/threonine kinase 10
|
4.97103
|
|
STIMATE
|
STIM activating enhancer
|
4.79925
|
|
NOTCH1
|
notch 1
|
4.74973
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.58331
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.46058
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
3.1829
|
|
TBP
|
TATA box binding protein
|
3.17569
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
3.16962
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
3.16015
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.94669
|
|
CHN1
|
chimerin 1
|
2.80583
|
|
LOXL1
|
lysyl oxidase-like 1
|
2.75936
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.68248
|
|
LYVE1
|
lymphatic vessel endothelial hyaluronan receptor 1
|
2.27438
|
|
SATB1
|
SATB homeobox 1
|
2.26504
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.264
|
|
EAPP
|
E2F-associated phosphoprotein
|
2.23892
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.17606
|
|
CTSL
|
cathepsin L
|
2.13566
|
|
TGFBR2
|
transforming growth factor, beta receptor II (70/80kDa)
|
2.10089
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.06857
|
|
PGGHG
|
protein-glucosylgalactosylhydroxylysine glucosidase
|
2.04749
|
|
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
|
2.01027
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-7.06535
|
|
CCNB1
|
cyclin B1
|
-5.19792
|
|
ZNF586
|
zinc finger protein 586
|
-4.9525
|
|
PEG10
|
paternally expressed 10
|
-4.83728
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.82965
|
|
MAP7
|
microtubule-associated protein 7
|
-4.35987
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.97361
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.54828
|
|
EGF
|
epidermal growth factor
|
-3.41539
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.99703
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.93473
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.92899
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-2.88883
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-2.85538
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.79005
|
|
THAP11
|
THAP domain containing 11
|
-2.58647
|
|
PLK1
|
polo-like kinase 1
|
-2.57438
|
|
SOAT2
|
sterol O-acyltransferase 2
|
-2.44998
|
|
CD58
|
CD58 molecule
|
-2.29259
|
|
MTERF4
|
mitochondrial transcription termination factor 4
|
-2.28659
|
|
SCAND1
|
SCAN domain containing 1
|
-2.18887
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.1847
|
|
USP6NL
|
USP6 N-terminal like
|
-2.13792
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.07824
|
|
ZNF154
|
zinc finger protein 154
|
-2.06192
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-2.03693
|
