CRCGN013_HEPG2_24H:J07 Gene Set
Genes
47 genes differentially expressed following the CRCGN013_HEPG2_24H:J07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MYLK
|
myosin light chain kinase
|
7.48631
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
4.33219
|
|
E2F2
|
E2F transcription factor 2
|
4.18109
|
|
SFTPB
|
surfactant protein B
|
4.09436
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
3.61884
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.22739
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
3.02718
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.8781
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.76551
|
|
UBQLN2
|
ubiquilin 2
|
2.7157
|
|
PFKL
|
phosphofructokinase, liver
|
2.71271
|
|
CYCS
|
cytochrome c, somatic
|
2.69243
|
|
SLC27A3
|
solute carrier family 27 (fatty acid transporter), member 3
|
2.56194
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.5443
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.4506
|
|
DDX10
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
|
2.40965
|
|
WASF3
|
WAS protein family, member 3
|
2.40258
|
|
LCN2
|
lipocalin 2
|
2.33545
|
|
BCAS3
|
breast carcinoma amplified sequence 3
|
2.30101
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
2.21196
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.15373
|
|
HNRNPC
|
heterogeneous nuclear ribonucleoprotein C (C1/C2)
|
2.1487
|
|
CYP4B1
|
cytochrome P450, family 4, subfamily B, polypeptide 1
|
2.0543
|
|
HMOX1
|
heme oxygenase 1
|
2.00494
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-10.0
|
|
ZNF586
|
zinc finger protein 586
|
-7.03625
|
|
CDC20
|
cell division cycle 20
|
-6.55967
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-5.44066
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.86549
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.68028
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.34937
|
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding
|
-3.11927
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-2.97797
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-2.89593
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.84485
|
|
ABCF3
|
ATP-binding cassette, sub-family F (GCN20), member 3
|
-2.60972
|
|
ZNF134
|
zinc finger protein 134
|
-2.5933
|
|
DNTTIP2
|
deoxynucleotidyltransferase, terminal, interacting protein 2
|
-2.5755
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.46203
|
|
PEG10
|
paternally expressed 10
|
-2.30169
|
|
AARS1
|
alanyl-tRNA synthetase 1
|
-2.26304
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.24558
|
|
GOLT1B
|
golgi transport 1B
|
-2.09782
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.09394
|
|
NME3
|
NME/NM23 nucleoside diphosphate kinase 3
|
-2.09386
|
|
RTCA
|
RNA 3'-terminal phosphate cyclase
|
-2.08854
|
|
CYTIP
|
cytohesin 1 interacting protein
|
-2.06009
|
