CRCGN013_HEPG2_24H:J11 Gene Set
Genes
45 genes differentially expressed following the CRCGN013_HEPG2_24H:J11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LCN2
|
lipocalin 2
|
6.24004
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
5.71512
|
|
E2F2
|
E2F transcription factor 2
|
4.60297
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.19309
|
|
STK10
|
serine/threonine kinase 10
|
3.91968
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
3.43499
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.06667
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
2.64975
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.6398
|
|
MCUR1
|
mitochondrial calcium uniporter regulator 1
|
2.33461
|
|
CCNF
|
cyclin F
|
2.28652
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.25571
|
|
SNX7
|
sorting nexin 7
|
2.2557
|
|
CEP57
|
centrosomal protein 57kDa
|
2.24062
|
|
RAB11FIP1
|
RAB11 family interacting protein 1 (class I)
|
2.22517
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.17567
|
|
CCNH
|
cyclin H
|
2.14665
|
|
PRR15L
|
proline rich 15-like
|
2.13015
|
|
ACKR1
|
atypical chemokine receptor 1 (Duffy blood group)
|
2.12572
|
|
BATF3
|
basic leucine zipper transcription factor, ATF-like 3
|
2.12402
|
|
ATP1A4
|
ATPase, Na+/K+ transporting, alpha 4 polypeptide
|
2.09096
|
|
GPATCH8
|
G patch domain containing 8
|
2.07357
|
|
APOO
|
apolipoprotein O
|
2.06305
|
|
MKNK1
|
MAP kinase interacting serine/threonine kinase 1
|
2.02597
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
GNAS
|
GNAS complex locus
|
-6.41862
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-4.45054
|
|
CDC20
|
cell division cycle 20
|
-4.34551
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.32881
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-4.15324
|
|
ADI1
|
acireductone dioxygenase 1
|
-4.08472
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-4.02673
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.74623
|
|
CCNB2
|
cyclin B2
|
-3.52288
|
|
GDF15
|
growth differentiation factor 15
|
-3.23881
|
|
RHEB
|
Ras homolog enriched in brain
|
-3.07689
|
|
SNX11
|
sorting nexin 11
|
-3.04505
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.89282
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.80939
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.57946
|
|
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1
|
-2.49523
|
|
WASHC4
|
WASH complex subunit 4
|
-2.3698
|
|
PCP4
|
Purkinje cell protein 4
|
-2.22796
|
|
HSD17B6
|
hydroxysteroid (17-beta) dehydrogenase 6
|
-2.14723
|
|
TKT
|
transketolase
|
-2.04002
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
-2.02313
|
