| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMSO perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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58 genes differentially expressed following the CRCGN013_HEPG2_24H:J14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPER1 | G protein-coupled estrogen receptor 1 | 4.71999 |
| CHMP6 | charged multivesicular body protein 6 | 3.49127 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 3.46582 |
| STIMATE | STIM activating enhancer | 3.30314 |
| ADRB2 | adrenoceptor beta 2, surface | 3.22354 |
| E2F2 | E2F transcription factor 2 | 3.02384 |
| ANO10 | anoctamin 10 | 2.9073 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 2.74503 |
| NOSIP | nitric oxide synthase interacting protein | 2.62656 |
| EPHB2 | EPH receptor B2 | 2.60728 |
| MELK | maternal embryonic leucine zipper kinase | 2.55667 |
| KLK15 | kallikrein-related peptidase 15 | 2.55643 |
| UBQLN2 | ubiquilin 2 | 2.52378 |
| LCN2 | lipocalin 2 | 2.49658 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 2.48049 |
| ACSM2A | acyl-CoA synthetase medium-chain family member 2A | 2.47701 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.38689 |
| HDGFL3 | HDGF like 3 | 2.36523 |
| MINDY1 | MINDY lysine 48 deubiquitinase 1 | 2.33948 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 2.21332 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | 2.17722 |
| GRIN2D | glutamate receptor, ionotropic, N-methyl D-aspartate 2D | 2.16548 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.1596 |
| KLHL9 | kelch-like family member 9 | 2.14916 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 2.14587 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) | 2.12955 |
| ATP11B | ATPase, class VI, type 11B | 2.11782 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | 2.11636 |
| UPB1 | ureidopropionase, beta | 2.02819 |
| TLR4 | toll-like receptor 4 | 2.01911 |
| LRP10 | low density lipoprotein receptor-related protein 10 | 2.00114 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -7.03236 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -6.26375 |
| CCNB2 | cyclin B2 | -5.51748 |
| PCNA | proliferating cell nuclear antigen | -5.26904 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.96483 |
| LAP3 | leucine aminopeptidase 3 | -3.64767 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -3.60041 |
| GDF15 | growth differentiation factor 15 | -3.57656 |
| TSPAN4 | tetraspanin 4 | -3.45328 |
| CD320 | CD320 molecule | -3.44214 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.41732 |
| GOLT1B | golgi transport 1B | -3.37156 |
| VDAC1 | voltage-dependent anion channel 1 | -3.36702 |
| CHMP4B | charged multivesicular body protein 4B | -3.07917 |
| TLCD3A | TLC domain containing 3A | -2.77331 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -2.59846 |
| DSG2 | desmoglein 2 | -2.3972 |
| RHEB | Ras homolog enriched in brain | -2.39033 |
| TES | testin LIM domain protein | -2.32875 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -2.3281 |
| CPNE3 | copine III | -2.23355 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.20578 |
| FAT1 | FAT atypical cadherin 1 | -2.20492 |
| GNAS | GNAS complex locus | -2.14722 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -2.11345 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -2.02763 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -2.01155 |
