| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMSO perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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44 genes differentially expressed following the CRCGN013_HEPG2_24H:J15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 8.92331 |
| LCN2 | lipocalin 2 | 7.36701 |
| GPATCH8 | G patch domain containing 8 | 5.10313 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.83392 |
| ADRB2 | adrenoceptor beta 2, surface | 4.79868 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.3044 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 3.93568 |
| SSBP2 | single-stranded DNA binding protein 2 | 3.66748 |
| CHN1 | chimerin 1 | 3.5589 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.55101 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.49319 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 3.42945 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 3.2197 |
| AMDHD2 | amidohydrolase domain containing 2 | 3.00394 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 2.94483 |
| CHEK2 | checkpoint kinase 2 | 2.92175 |
| DIPK1A | divergent protein kinase domain 1A | 2.77725 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.73977 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 2.65417 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.46904 |
| ACP6 | acid phosphatase 6, lysophosphatidic | 2.27329 |
| USP39 | ubiquitin specific peptidase 39 | 2.23041 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.18225 |
| PLIN3 | perilipin 3 | 2.12778 |
| VAMP5 | vesicle-associated membrane protein 5 | 2.02873 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ADI1 | acireductone dioxygenase 1 | -4.95854 |
| THAP11 | THAP domain containing 11 | -4.66062 |
| GNAS | GNAS complex locus | -4.5632 |
| B4GAT1 | beta-1,4-glucuronyltransferase 1 | -3.97332 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.85934 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.85384 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -3.74219 |
| GDF15 | growth differentiation factor 15 | -3.5583 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.48201 |
| CCNB2 | cyclin B2 | -3.29843 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.03127 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -2.84003 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -2.35276 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.29809 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa | -2.24731 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | -2.2035 |
| PCNA | proliferating cell nuclear antigen | -2.18591 |
| SUCO | SUN domain containing ossification factor | -2.13913 |
| MATCAP2 | microtubule associated tyrosine carboxypeptidase 2 | -2.10931 |
