| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMSO perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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60 genes differentially expressed following the CRCGN013_HEPG2_24H:J16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 6.7964 |
| STK10 | serine/threonine kinase 10 | 6.37291 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 4.45477 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.55628 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 3.1717 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.13807 |
| TBP | TATA box binding protein | 2.95982 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | 2.84542 |
| E2F2 | E2F transcription factor 2 | 2.83318 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 2.73596 |
| CCNF | cyclin F | 2.52778 |
| S1PR2 | sphingosine-1-phosphate receptor 2 | 2.42298 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.40696 |
| PRKCH | protein kinase C, eta | 2.39966 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.37465 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.30536 |
| LSP1 | lymphocyte-specific protein 1 | 2.22743 |
| ZNF761 | zinc finger protein 761 | 2.21906 |
| STIMATE | STIM activating enhancer | 2.17989 |
| FPGS | folylpolyglutamate synthase | 2.17724 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.15897 |
| FFAR2 | free fatty acid receptor 2 | 2.15472 |
| TMEM121 | transmembrane protein 121 | 2.13003 |
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | 2.12862 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 2.09733 |
| RNFT2 | ring finger protein, transmembrane 2 | 2.0806 |
| LOC100533997 | MAGEA10-MAGEA5 readthrough | 2.04116 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.03614 |
| MAGEA2B | melanoma antigen family A2B | 2.0333 |
| CD302 | CD302 molecule | 2.00758 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -5.18346 |
| CCNB2 | cyclin B2 | -4.73842 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.58389 |
| VAT1 | vesicle amine transport 1 | -4.04662 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.67176 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -3.58562 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -3.5522 |
| RAI14 | retinoic acid induced 14 | -3.42444 |
| NUP85 | nucleoporin 85kDa | -3.30398 |
| TENT4A | terminal nucleotidyltransferase 4A | -3.24418 |
| EDN1 | endothelin 1 | -2.97631 |
| YME1L1 | YME1-like 1 ATPase | -2.82059 |
| SNX11 | sorting nexin 11 | -2.79738 |
| CCNB1 | cyclin B1 | -2.72601 |
| CTSD | cathepsin D | -2.70114 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.54733 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.38418 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.37804 |
| LDHD | lactate dehydrogenase D | -2.36088 |
| EXT1 | exostosin glycosyltransferase 1 | -2.22104 |
| EPHA4 | EPH receptor A4 | -2.21609 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -2.11381 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.11295 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | -2.09421 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.07437 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 | -2.0678 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -2.0511 |
| IRS1 | insulin receptor substrate 1 | -2.04258 |
| RGS18 | regulator of G-protein signaling 18 | -2.03913 |
| HTRA1 | HtrA serine peptidase 1 | -2.00395 |
