CRCGN013_HEPG2_24H:J17 Gene Set
Genes
32 genes differentially expressed following the CRCGN013_HEPG2_24H:J17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CHN1
|
chimerin 1
|
6.0733
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
5.02208
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
4.94092
|
|
LCN2
|
lipocalin 2
|
4.842
|
|
UBQLN2
|
ubiquilin 2
|
4.78261
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
4.74714
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
3.8588
|
|
DNMT3A
|
DNA (cytosine-5-)-methyltransferase 3 alpha
|
2.88077
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.87096
|
|
MYLK
|
myosin light chain kinase
|
2.61885
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
2.54351
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
2.51747
|
|
E2F2
|
E2F transcription factor 2
|
2.50213
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.25279
|
|
RAB11FIP1
|
RAB11 family interacting protein 1 (class I)
|
2.18416
|
|
EVL
|
Enah/Vasp-like
|
2.09679
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.07493
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-7.02061
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-5.09477
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.76151
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-4.53647
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-3.91132
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.88432
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.42903
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.07213
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.00976
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.53004
|
|
GDPD5
|
glycerophosphodiester phosphodiesterase domain containing 5
|
-2.38534
|
|
MED23
|
mediator complex subunit 23
|
-2.14613
|
|
ETS1
|
v-ets avian erythroblastosis virus E26 oncogene homolog 1
|
-2.10285
|
|
CD320
|
CD320 molecule
|
-2.02886
|
|
SNX11
|
sorting nexin 11
|
-2.02762
|
