CRCGN013_HEPG2_24H:J18 Gene Set
Genes
51 genes differentially expressed following the CRCGN013_HEPG2_24H:J18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
6.24926
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
4.68389
|
|
CYCS
|
cytochrome c, somatic
|
4.47777
|
|
CHN1
|
chimerin 1
|
4.24826
|
|
MAP7
|
microtubule-associated protein 7
|
4.16189
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
3.7619
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
3.75176
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
3.74026
|
|
SATB1
|
SATB homeobox 1
|
3.69027
|
|
ZNF589
|
zinc finger protein 589
|
3.48801
|
|
UBQLN2
|
ubiquilin 2
|
3.22577
|
|
CCDC92
|
coiled-coil domain containing 92
|
3.22251
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.16197
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.07291
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
3.0525
|
|
LCN2
|
lipocalin 2
|
2.98922
|
|
E2F2
|
E2F transcription factor 2
|
2.94075
|
|
MYLK
|
myosin light chain kinase
|
2.91331
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.90958
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
2.83654
|
|
STK10
|
serine/threonine kinase 10
|
2.58927
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.52806
|
|
XPNPEP1
|
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
|
2.5042
|
|
USP6NL
|
USP6 N-terminal like
|
2.40649
|
|
SFTPB
|
surfactant protein B
|
2.40115
|
|
PCDHB11
|
protocadherin beta 11
|
2.29476
|
|
GPATCH8
|
G patch domain containing 8
|
2.08777
|
|
AKIRIN1
|
akirin 1
|
2.03554
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-6.62091
|
|
LDHD
|
lactate dehydrogenase D
|
-6.48784
|
|
TUBB6
|
tubulin, beta 6 class V
|
-3.53538
|
|
DNM1L
|
dynamin 1-like
|
-3.37524
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-3.37107
|
|
CDC25B
|
cell division cycle 25B
|
-3.22289
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.1612
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-3.11073
|
|
PLK1
|
polo-like kinase 1
|
-3.08483
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.99459
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-2.97682
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-2.91816
|
|
TXNRD1
|
thioredoxin reductase 1
|
-2.79823
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.68245
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.64554
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-2.5383
|
|
DUSP11
|
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
|
-2.32989
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.23294
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.22711
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-2.19159
|
|
SYNGAP1
|
synaptic Ras GTPase activating protein 1
|
-2.17184
|
|
DCK
|
deoxycytidine kinase
|
-2.07822
|
|
CKAP2
|
cytoskeleton associated protein 2
|
-2.0021
|
