CRCGN013_HEPG2_24H:J21 Gene Set
Genes
34 genes differentially expressed following the CRCGN013_HEPG2_24H:J21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
SSBP2
|
single-stranded DNA binding protein 2
|
4.59091
|
|
CBR3
|
carbonyl reductase 3
|
4.06574
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.73711
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.72556
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.54888
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.52218
|
|
E2F2
|
E2F transcription factor 2
|
3.38466
|
|
MAMLD1
|
mastermind-like domain containing 1
|
3.2683
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.02892
|
|
STXBP2
|
syntaxin binding protein 2
|
2.88767
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
2.83718
|
|
CYCS
|
cytochrome c, somatic
|
2.81892
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.75697
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
2.64114
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
2.50871
|
|
STK10
|
serine/threonine kinase 10
|
2.21502
|
|
DOK5
|
docking protein 5
|
2.05088
|
|
UQCRH
|
ubiquinol-cytochrome c reductase hinge protein
|
2.04382
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CDC20
|
cell division cycle 20
|
-6.69318
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-6.49656
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.92337
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-3.59174
|
|
FASTKD5
|
FAST kinase domains 5
|
-2.97722
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.96005
|
|
DNM1L
|
dynamin 1-like
|
-2.92945
|
|
CD320
|
CD320 molecule
|
-2.89348
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.84283
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-2.83438
|
|
ZNF586
|
zinc finger protein 586
|
-2.78
|
|
EGF
|
epidermal growth factor
|
-2.61627
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-2.49891
|
|
RNF167
|
ring finger protein 167
|
-2.2685
|
|
PLVAP
|
plasmalemma vesicle associated protein
|
-2.15708
|
|
SMURF2
|
SMAD specific E3 ubiquitin protein ligase 2
|
-2.04349
|
