| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | CH-223191 2.62 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
57 genes differentially expressed following the CRCGN013_HEPG2_24H:J22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NOTCH1 | notch 1 | 4.7389 |
| IL1B | interleukin 1, beta | 4.71372 |
| LCN2 | lipocalin 2 | 4.62216 |
| ADRB2 | adrenoceptor beta 2, surface | 4.52314 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.44893 |
| SSBP2 | single-stranded DNA binding protein 2 | 4.25744 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 4.14171 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 4.13038 |
| ATP11B | ATPase, class VI, type 11B | 3.72809 |
| CHN1 | chimerin 1 | 3.58192 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 3.31835 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 3.08355 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 3.01269 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.96886 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 2.93581 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 2.90557 |
| EGF | epidermal growth factor | 2.36872 |
| SQOR | sulfide quinone oxidoreductase | 2.36501 |
| EPHA3 | EPH receptor A3 | 2.35334 |
| ADGRA2 | adhesion G protein-coupled receptor A2 | 2.3175 |
| PDGFD | platelet derived growth factor D | 2.25915 |
| TRAPPC4 | trafficking protein particle complex 4 | 2.21977 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 2.18039 |
| NLGN3 | neuroligin 3 | 2.17622 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.14148 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | 2.13621 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 2.13044 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.08697 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -7.48714 |
| SCAND1 | SCAN domain containing 1 | -5.86857 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -4.20951 |
| TLCD3A | TLC domain containing 3A | -4.1942 |
| NGRN | neugrin, neurite outgrowth associated | -3.85484 |
| CCNB2 | cyclin B2 | -3.8251 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -3.7811 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.47179 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -3.38419 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -3.06168 |
| ICAM3 | intercellular adhesion molecule 3 | -2.88459 |
| FGFR4 | fibroblast growth factor receptor 4 | -2.87681 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -2.78313 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.69564 |
| MAP7 | microtubule-associated protein 7 | -2.6845 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -2.52477 |
| CCP110 | centriolar coiled coil protein 110kDa | -2.38554 |
| HSPB8 | heat shock 22kDa protein 8 | -2.37493 |
| TRAP1 | TNF receptor-associated protein 1 | -2.35672 |
| SLC35F2 | solute carrier family 35, member F2 | -2.30028 |
| HMOX2 | heme oxygenase 2 | -2.28956 |
| GNAS | GNAS complex locus | -2.26649 |
| SFTPD | surfactant protein D | -2.24837 |
| HERC2 | HECT and RLD domain containing E3 ubiquitin protein ligase 2 | -2.13407 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -2.11005 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -2.08136 |
| SDF2L1 | stromal cell-derived factor 2-like 1 | -2.06857 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.04758 |
| CCNB1 | cyclin B1 | -2.03866 |
