CRCGN013_HEPG2_24H:J23 Gene Set
Genes
48 genes differentially expressed following the CRCGN013_HEPG2_24H:J23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CHN1
|
chimerin 1
|
5.42898
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.95044
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
4.86823
|
|
LCN2
|
lipocalin 2
|
4.69761
|
|
MYLK
|
myosin light chain kinase
|
4.61132
|
|
SFTPB
|
surfactant protein B
|
4.34588
|
|
CBR3
|
carbonyl reductase 3
|
4.21882
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.896
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.19277
|
|
GATA2
|
GATA binding protein 2
|
2.84387
|
|
PRR15L
|
proline rich 15-like
|
2.8024
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.48869
|
|
HOOK2
|
hook microtubule-tethering protein 2
|
2.42282
|
|
TCFL5
|
transcription factor-like 5 (basic helix-loop-helix)
|
2.38648
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.32143
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.24838
|
|
HEBP1
|
heme binding protein 1
|
2.23127
|
|
TBP
|
TATA box binding protein
|
2.11581
|
|
PTPRG
|
protein tyrosine phosphatase, receptor type, G
|
2.0641
|
|
XK
|
X-linked Kx blood group
|
2.04783
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.0478
|
|
TGFBR2
|
transforming growth factor, beta receptor II (70/80kDa)
|
2.03105
|
|
TPSAB1
|
tryptase alpha/beta 1
|
2.01263
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-9.44602
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-9.00902
|
|
ZNF586
|
zinc finger protein 586
|
-7.95178
|
|
PCNA
|
proliferating cell nuclear antigen
|
-5.95565
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-5.09366
|
|
TRIB3
|
tribbles pseudokinase 3
|
-4.55251
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-4.00507
|
|
GNAS
|
GNAS complex locus
|
-3.51082
|
|
ZNF587B
|
zinc finger protein 587B
|
-2.79069
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.71625
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.67701
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-2.58881
|
|
TLR4
|
toll-like receptor 4
|
-2.5577
|
|
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1
|
-2.45185
|
|
ZNF134
|
zinc finger protein 134
|
-2.38706
|
|
CCNB1
|
cyclin B1
|
-2.37426
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.34973
|
|
MAP7
|
microtubule-associated protein 7
|
-2.2357
|
|
TSEN34
|
TSEN34 tRNA splicing endonuclease subunit
|
-2.18715
|
|
ZNF304
|
zinc finger protein 304
|
-2.16481
|
|
NEUROG1
|
neurogenin 1
|
-2.12006
|
|
ZNF550
|
zinc finger protein 550
|
-2.11772
|
|
ETFB
|
electron-transfer-flavoprotein, beta polypeptide
|
-2.11552
|
|
AGO4
|
argonaute RISC catalytic component 4
|
-2.0972
|
|
PPWD1
|
peptidylprolyl isomerase domain and WD repeat containing 1
|
-2.04558
|
