CRCGN013_HEPG2_24H:K02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description o-phenylenediamine.2hcl 20.4 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

914 genes differentially expressed following the CRCGN013_HEPG2_24H:K02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABHD4 abhydrolase domain containing 4 10.0
BLCAP bladder cancer associated protein 9.35791
INPP1 inositol polyphosphate-1-phosphatase 9.28218
CCDC92 coiled-coil domain containing 92 9.274
STX1A syntaxin 1A (brain) 8.06046
DDB2 damage-specific DNA binding protein 2, 48kDa 7.92187
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 7.67701
MICALL1 MICAL-like 1 7.6364
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 7.44823
TUBB6 tubulin, beta 6 class V 7.38595
LRP10 low density lipoprotein receptor-related protein 10 6.99467
DYNLT3 dynein, light chain, Tctex-type 3 6.97407
DUSP14 dual specificity phosphatase 14 6.81993
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 6.68018
CNPY3 canopy FGF signaling regulator 3 6.66333
PPARG peroxisome proliferator-activated receptor gamma 6.40695
CDPF1 cysteine-rich, DPF motif domain containing 1 6.37529
TIMP2 TIMP metallopeptidase inhibitor 2 6.27285
CTSL cathepsin L 6.25245
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 6.15807
ANKRD10 ankyrin repeat domain 10 6.11464
FOSL1 FOS-like antigen 1 6.02861
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 5.98858
IL4R interleukin 4 receptor 5.93838
KEAP1 kelch-like ECH-associated protein 1 5.83374
KIFBP kinesin family binding protein 5.67562
PRAF2 PRA1 domain family, member 2 5.64632
TXNRD1 thioredoxin reductase 1 5.63682
KCNK1 potassium channel, two pore domain subfamily K, member 1 5.48838
KLHL21 kelch-like family member 21 5.48259
ADGRE5 adhesion G protein-coupled receptor E5 5.38576
LSR lipolysis stimulated lipoprotein receptor 5.32191
GADD45A growth arrest and DNA-damage-inducible, alpha 5.3075
FOS FBJ murine osteosarcoma viral oncogene homolog 5.2696
GPC1 glypican 1 5.22542
SLC75A1 solute carrier family 75 member 1 5.22373
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 5.18888
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 5.18851
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 5.16381
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 5.04795
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 5.0176
KHDC4 KH domain containing 4, pre-mRNA splicing factor 5.00829
TERF2IP telomeric repeat binding factor 2, interacting protein 4.95561
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 4.82434
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 4.73369
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 4.57994
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 4.57724
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 4.53627
CHN1 chimerin 1 4.53498
MAP7D1 MAP7 domain containing 1 4.50137
BAD BCL2-associated agonist of cell death 4.39156
MOK MOK protein kinase 4.37698
IGFBP3 insulin-like growth factor binding protein 3 4.34931
TOR1A torsin family 1, member A (torsin A) 4.27761
CASC3 cancer susceptibility candidate 3 4.23613
HSPA1A heat shock 70kDa protein 1A 4.22389
CSRNP2 cysteine-serine-rich nuclear protein 2 4.17832
SQOR sulfide quinone oxidoreductase 4.12356
ULK1 unc-51 like autophagy activating kinase 1 4.00871
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 4.00494
TWF2 twinfilin actin binding protein 2 3.98979
ADRB2 adrenoceptor beta 2, surface 3.98531
VAT1 vesicle amine transport 1 3.98363
DUSP6 dual specificity phosphatase 6 3.97748
PRKCQ protein kinase C, theta 3.95952
TBPL1 TBP-like 1 3.94081
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 3.92037
KDM5A lysine (K)-specific demethylase 5A 3.89887
ZNF226 zinc finger protein 226 3.89579
ALAS1 5'-aminolevulinate synthase 1 3.89109
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 3.86762
ADGRG1 adhesion G protein-coupled receptor G1 3.84493
CAPN1 calpain 1, (mu/I) large subunit 3.81107
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 3.80929
COL7A1 collagen, type VII, alpha 1 3.78403
DDR1 discoidin domain receptor tyrosine kinase 1 3.7081
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.6851
BAX BCL2-associated X protein 3.66057
LRRC41 leucine rich repeat containing 41 3.65997
CCND3 cyclin D3 3.65793
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.65431
RXYLT1 ribitol xylosyltransferase 1 3.6521
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 3.64469
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 3.61597
MCOLN1 mucolipin 1 3.56646
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 3.52124
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 3.48586
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated 3.48378
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 3.47911
TMEM115 transmembrane protein 115 3.45364
TP53I3 tumor protein p53 inducible protein 3 3.43949
SMAD3 SMAD family member 3 3.41834
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 3.3975
GPR87 G protein-coupled receptor 87 3.39541
CEMIP2 cell migration inducing hyaluronidase 2 3.38074
PHTF1 putative homeodomain transcription factor 1 3.37452
LCN2 lipocalin 2 3.3649
MMP1 matrix metallopeptidase 1 3.36027
SKIC2 SKI2 subunit of superkiller complex 3.35597
FAM193A family with sequence similarity 193, member A 3.35417
TKTL1 transketolase-like 1 3.33481
HCFC2 host cell factor C2 3.3156
RNF25 ring finger protein 25 3.31416
NR1H2 nuclear receptor subfamily 1, group H, member 2 3.30884
RBM10 RNA binding motif protein 10 3.30705
TESK1 testis-specific kinase 1 3.28292
LOC122526780 uncharacterized LOC122526780 3.27384
FNBP4 formin binding protein 4 3.26582
RAB11FIP1 RAB11 family interacting protein 1 (class I) 3.26334
CLK3 CDC-like kinase 3 3.24916
LAMB3 laminin, beta 3 3.20822
FFAR3 free fatty acid receptor 3 3.20352
SCAND1 SCAN domain containing 1 3.1979
IER3 immediate early response 3 3.19517
SNAP25 synaptosomal-associated protein, 25kDa 3.1906
MVP major vault protein 3.1904
PANX1 pannexin 1 3.19016
FRS2 fibroblast growth factor receptor substrate 2 3.1676
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 3.16079
ZNF282 zinc finger protein 282 3.14989
IL11 interleukin 11 3.1472
PNKP polynucleotide kinase 3'-phosphatase 3.14016
PORCN porcupine homolog (Drosophila) 3.13477
PARP12 poly (ADP-ribose) polymerase family, member 12 3.12469
AKAP17A A kinase (PRKA) anchor protein 17A 3.11846
ZNF45 zinc finger protein 45 3.10353
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 3.0783
GPN2 GPN-loop GTPase 2 3.07638
NISCH nischarin 3.07607
E2F2 E2F transcription factor 2 3.07549
MBOAT7 membrane bound O-acyltransferase domain containing 7 3.07544
NOTCH1 notch 1 3.06738
RAP1GAP RAP1 GTPase activating protein 3.06413
SNAI2 snail family zinc finger 2 3.04233
TDP2 tyrosyl-DNA phosphodiesterase 2 3.04047
TFE3 transcription factor binding to IGHM enhancer 3 3.03788
MAD2L1BP MAD2L1 binding protein 3.03048
LIF leukemia inhibitory factor 3.00747
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) 3.00015
ELAC2 elaC ribonuclease Z 2 2.99963
TRIM8 tripartite motif containing 8 2.98651
GSTZ1 glutathione S-transferase zeta 1 2.96703
XPC xeroderma pigmentosum, complementation group C 2.94703
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 2.93869
TOMM34 translocase of outer mitochondrial membrane 34 2.93354
ZNF227 zinc finger protein 227 2.93281
MICA MHC class I polypeptide-related sequence A 2.93279
PLEC plectin 2.92432
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 2.92275
MAMLD1 mastermind-like domain containing 1 2.91383
ZXDC ZXD family zinc finger C 2.9099
ZNF222 zinc finger protein 222 2.90556
PKM pyruvate kinase, muscle 2.89893
DGKA diacylglycerol kinase, alpha 80kDa 2.893
BPHL biphenyl hydrolase-like (serine hydrolase) 2.89123
CSNK1E casein kinase 1, epsilon 2.8844
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 2.87955
PRKD2 protein kinase D2 2.86612
TRNAU1AP tRNA selenocysteine 1 associated protein 1 2.86267
PTGES prostaglandin E synthase 2.85839
RSPH10B2 radial spoke head 10 homolog B2 (Chlamydomonas) 2.85481
PSPC1 paraspeckle component 1 2.85234
TIGAR TP53 induced glycolysis regulatory phosphatase 2.84289
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 2.82226
MINDY1 MINDY lysine 48 deubiquitinase 1 2.82077
CD8A CD8a molecule 2.81654
KLF5 Kruppel-like factor 5 (intestinal) 2.81542
KLHL36 kelch-like family member 36 2.81038
SLCO3A1 solute carrier organic anion transporter family, member 3A1 2.79885
RALB v-ral simian leukemia viral oncogene homolog B 2.77876
MICALL2 MICAL-like 2 2.7787
THUMPD2 THUMP domain containing 2 2.77653
PTPN6 protein tyrosine phosphatase, non-receptor type 6 2.77377
RGPD1 RANBP2-like and GRIP domain containing 1 2.76237
CAVIN3 caveolae associated protein 3 2.75803
MSL1 male-specific lethal 1 homolog (Drosophila) 2.75726
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C 2.75237
TLE3 transducin-like enhancer of split 3 2.74881
SSBP2 single-stranded DNA binding protein 2 2.74498
ASCC3 activating signal cointegrator 1 complex subunit 3 2.74113
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 2.74076
GNLY granulysin 2.74042
TXLNA taxilin alpha 2.73437
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 2.72973
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 2.72956
LPAR2 lysophosphatidic acid receptor 2 2.72646
NSUN3 NOP2/Sun domain family, member 3 2.72569
CSK c-src tyrosine kinase 2.72164
SYNRG synergin, gamma 2.71439
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 2.71306
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 2.70415
GATA3 GATA binding protein 3 2.70312
PARP8 poly (ADP-ribose) polymerase family, member 8 2.70246
TRIM13 tripartite motif containing 13 2.69693
LAMC2 laminin, gamma 2 2.69534
NT5C 5', 3'-nucleotidase, cytosolic 2.69052
NIT1 nitrilase 1 2.68573
SCPEP1 serine carboxypeptidase 1 2.68558
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11 2.68095
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2 2.66914
PHIP pleckstrin homology domain interacting protein 2.66839
HBEGF heparin-binding EGF-like growth factor 2.66615
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast) 2.66269
INTS5 integrator complex subunit 5 2.65813
UIMC1 ubiquitin interaction motif containing 1 2.65786
GABARAPL1 GABA(A) receptor-associated protein like 1 2.64578
OSGIN1 oxidative stress induced growth inhibitor 1 2.638
PCGF3 polycomb group ring finger 3 2.63408
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 2.63253
ATG9A autophagy related 9A 2.62843
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 2.62772
ZNF557 zinc finger protein 557 2.62703
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2.62392
SLFN12 schlafen family member 12 2.61284
STRN4 striatin, calmodulin binding protein 4 2.60737
ZFTRAF1 zinc finger TRAF-type containing 1 2.60328
BAG2 BCL2-associated athanogene 2 2.59567
PIH1D1 PIH1 domain containing 1 2.59363
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 2.59171
REG1B regenerating islet-derived 1 beta 2.57377
TCTA T-cell leukemia translocation altered 2.56926
CSAD cysteine sulfinic acid decarboxylase 2.56875
MARK4 MAP/microtubule affinity-regulating kinase 4 2.56483
RHOF ras homolog family member F (in filopodia) 2.56444
ATG2A autophagy related 2A 2.56227
PINK1 PTEN induced putative kinase 1 2.5616
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 2.55957
BECN1 beclin 1, autophagy related 2.55818
POPDC3 popeye domain containing 3 2.55811
MAP3K14 mitogen-activated protein kinase kinase kinase 14 2.55352
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 2.55034
GFPT2 glutamine-fructose-6-phosphate transaminase 2 2.54675
KLRC4-KLRK1 KLRC4-KLRK1 readthrough 2.54582
MAST2 microtubule associated serine/threonine kinase 2 2.5458
IL2RA interleukin 2 receptor, alpha 2.54188
INPPL1 inositol polyphosphate phosphatase-like 1 2.53552
GPRC5C G protein-coupled receptor, class C, group 5, member C 2.53549
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 2.53477
NBR1 neighbor of BRCA1 gene 1 2.53449
POMT2 protein-O-mannosyltransferase 2 2.53431
LTC4S leukotriene C4 synthase 2.53362
TUBG2 tubulin, gamma 2 2.51349
C6ORF89 chromosome 6 open reading frame 89 2.50575
RIN1 Ras and Rab interactor 1 2.49952
RAB21 RAB21, member RAS oncogene family 2.49888
YIPF3 Yip1 domain family, member 3 2.49705
FMNL1 formin-like 1 2.49584
SQSTM1 sequestosome 1 2.49427
ZNF79 zinc finger protein 79 2.49214
ZW10 zw10 kinetochore protein 2.49205
STX4 syntaxin 4 2.4877
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 2.48729
C2CD3 C2 calcium-dependent domain containing 3 2.48593
ERCC3 excision repair cross-complementation group 3 2.48224
MAPK7 mitogen-activated protein kinase 7 2.48199
UST uronyl-2-sulfotransferase 2.47824
TCP11L1 t-complex 11, testis-specific-like 1 2.4779
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 2.47712
PLPP1 phospholipid phosphatase 1 2.47622
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 2.46916
THSD1 thrombospondin, type I, domain containing 1 2.46434
CD9 CD9 molecule 2.46383
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle) 2.45969
EPN2 epsin 2 2.45612
ELF4 E74-like factor 4 (ets domain transcription factor) 2.45483
TBCC tubulin folding cofactor C 2.45435
NT5M 5',3'-nucleotidase, mitochondrial 2.4508
TNIP1 TNFAIP3 interacting protein 1 2.43952
CPM carboxypeptidase M 2.43631
PNMA8A PNMA family member 8A 2.43397
MUC2 mucin 2, oligomeric mucus/gel-forming 2.43113
RGL2 ral guanine nucleotide dissociation stimulator-like 2 2.43049
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 2.42818
OFD1 oral-facial-digital syndrome 1 2.42802
ZNF212 zinc finger protein 212 2.42582
PPIE peptidylprolyl isomerase E (cyclophilin E) 2.42522
SLC6A16 solute carrier family 6, member 16 2.42394
CLIP4 CAP-GLY domain containing linker protein family, member 4 2.41865
PHF1 PHD finger protein 1 2.41527
ZYX zyxin 2.41264
H2BC21 H2B clustered histone 21 2.4104
ROGDI rogdi homolog (Drosophila) 2.40997
EPHB2 EPH receptor B2 2.40203
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 2.39526
ZDHHC17 zinc finger, DHHC-type containing 17 2.39306
CUL7 cullin 7 2.38566
TBX3 T-box 3 2.38507
CCL2 chemokine (C-C motif) ligand 2 2.37803
KAT2A K(lysine) acetyltransferase 2A 2.37061
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 2.36957
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 2.36642
PLAU plasminogen activator, urokinase 2.36529
SIN3B SIN3 transcription regulator family member B 2.36246
FRYL FRY-like 2.36241
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 2.35791
NME3 NME/NM23 nucleoside diphosphate kinase 3 2.35766
CBR3 carbonyl reductase 3 2.3572
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 2.35316
ZNHIT2 zinc finger, HIT-type containing 2 2.34569
COL17A1 collagen, type XVII, alpha 1 2.34232
E4F1 E4F transcription factor 1 2.34123
BTG3 BTG family, member 3 2.34103
ZNF646 zinc finger protein 646 2.33911
LTK leukocyte receptor tyrosine kinase 2.33292
SYMPK symplekin 2.33198
FASTKD5 FAST kinase domains 5 2.32879
CDR2L cerebellar degeneration-related protein 2-like 2.32245
PCDHA10 protocadherin alpha 10 2.3192
PHLDA3 pleckstrin homology-like domain, family A, member 3 2.3145
SRPK3 SRSF protein kinase 3 2.30493
ZNF75D zinc finger protein 75D 2.3042
MMP3 matrix metallopeptidase 3 2.30222
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) 2.29147
TBC1D3G TBC1 domain family member 3G 2.28775
PROCR protein C receptor, endothelial 2.28571
ITPKC inositol-trisphosphate 3-kinase C 2.28208
LRFN4 leucine rich repeat and fibronectin type III domain containing 4 2.28012
KDM5C lysine (K)-specific demethylase 5C 2.27522
ZNF350 zinc finger protein 350 2.27492
NECTIN2 nectin cell adhesion molecule 2 2.27446
MAPKBP1 mitogen-activated protein kinase binding protein 1 2.26549
SPTBN4 spectrin, beta, non-erythrocytic 4 2.2647
CIDEC cell death-inducing DFFA-like effector c 2.26423
ZNF195 zinc finger protein 195 2.26423
PLD3 phospholipase D family, member 3 2.26053
CIC capicua transcriptional repressor 2.25908
SH3BP1 SH3-domain binding protein 1 2.25818
GPATCH3 G patch domain containing 3 2.25512
TCF15 transcription factor 15 (basic helix-loop-helix) 2.25499
CYTH2 cytohesin 2 2.25168
PIAS3 protein inhibitor of activated STAT, 3 2.24564
CSNK1G1 casein kinase 1, gamma 1 2.24465
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1 2.24397
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) 2.2429
AARSD1 alanyl-tRNA synthetase domain containing 1 2.24092
BTG2 BTG family, member 2 2.23924
UNKL unkempt family zinc finger-like 2.23528
FHIP2B FHF complex subunit HOOK interacting protein 2B 2.2346
SMIM5 small integral membrane protein 5 2.23444
EFNB2 ephrin-B2 2.23178
PIGG phosphatidylinositol glycan anchor biosynthesis, class G 2.23081
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 2.22511
PRRC2A proline-rich coiled-coil 2A 2.22396
ZNF268 zinc finger protein 268 2.2232
TEX11 testis expressed 11 2.2218
IL3RA interleukin 3 receptor, alpha (low affinity) 2.216
ST18 suppression of tumorigenicity 18, zinc finger 2.2154
SSX2 synovial sarcoma, X breakpoint 2 2.214
EPHA3 EPH receptor A3 2.21375
STAMBP STAM binding protein 2.21275
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 2.21211
RBMS1 RNA binding motif, single stranded interacting protein 1 2.20685
ANPEP alanyl (membrane) aminopeptidase 2.20282
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 2.20238
TBK1 TANK-binding kinase 1 2.2012
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 2.19832
PPY pancreatic polypeptide 2.19285
FTSJ3 FtsJ homolog 3 (E. coli) 2.18883
NINJ1 ninjurin 1 2.18781
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14 2.18559
TRAPPC6A trafficking protein particle complex 6A 2.18515
TIAM1 T-cell lymphoma invasion and metastasis 1 2.1831
ZFC3H1 zinc finger, C3H1-type containing 2.18246
RNF19B ring finger protein 19B 2.18139
GPR171 G protein-coupled receptor 171 2.17914
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 2.1736
MTCH1 mitochondrial carrier 1 2.1728
NCOR2 nuclear receptor corepressor 2 2.17162
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 2.17101
MYL5 myosin, light chain 5, regulatory 2.16825
STARD3 StAR-related lipid transfer (START) domain containing 3 2.16781
CAMTA2 calmodulin binding transcription activator 2 2.16544
ZNF34 zinc finger protein 34 2.16157
PPCDC phosphopantothenoylcysteine decarboxylase 2.15942
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 2.15886
APH1B APH1B gamma secretase subunit 2.15775
YJU2B YJU2 splicing factor homolog B 2.15525
TPGS1 tubulin polyglutamylase complex subunit 1 2.15473
OTULINL OTU deubiquitinase with linear linkage specificity like 2.14982
WDR26 WD repeat domain 26 2.14967
MSX2 msh homeobox 2 2.14854
SNW1 SNW domain containing 1 2.14817
TRIM68 tripartite motif containing 68 2.14599
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 2.13693
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 2.13662
OPRD1 opioid receptor, delta 1 2.13588
TMEM35B transmembrane protein 35B 2.13432
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 2.13264
RAD54L2 RAD54-like 2 (S. cerevisiae) 2.132
CTSZ cathepsin Z 2.13185
TRIM16 tripartite motif containing 16 2.12934
ZFP36 ZFP36 ring finger protein 2.12841
EAPP E2F-associated phosphoprotein 2.12541
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.12403
TUT7 terminal uridylyl transferase 7 2.11989
BRMS1L breast cancer metastasis-suppressor 1-like 2.11983
ZNF180 zinc finger protein 180 2.11962
MED17 mediator complex subunit 17 2.11766
NELFE negative elongation factor complex member E 2.11756
PAGE4 P antigen family, member 4 (prostate associated) 2.11665
EDC3 enhancer of mRNA decapping 3 2.11504
HAND2 heart and neural crest derivatives expressed 2 2.11499
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 2.11407
RNF40 ring finger protein 40, E3 ubiquitin protein ligase 2.11399
NCBP3 nuclear cap binding subunit 3 2.11351
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 2.10992
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 2.10708
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 2.10593
TMBIM1 transmembrane BAX inhibitor motif containing 1 2.10227
THBS4 thrombospondin 4 2.1008
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.09637
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 2.09578
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22 2.09527
FKRP fukutin related protein 2.09283
MYOF myoferlin 2.0916
ETFB electron-transfer-flavoprotein, beta polypeptide 2.09098
MUTYH mutY homolog 2.08622
MST1R macrophage stimulating 1 receptor 2.08449
GFI1 growth factor independent 1 transcription repressor 2.08371
PPP2R5B protein phosphatase 2, regulatory subunit B', beta 2.08217
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa 2.08168
EVX1 even-skipped homeobox 1 2.07273
SLC26A6 solute carrier family 26 (anion exchanger), member 6 2.07258
BBC3 BCL2 binding component 3 2.07164
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 2.07152
S100A2 S100 calcium binding protein A2 2.07082
SBF1 SET binding factor 1 2.06945
ELMO3 engulfment and cell motility 3 2.06821
PHC1 polyhomeotic homolog 1 (Drosophila) 2.06807
BTN2A1 butyrophilin, subfamily 2, member A1 2.06537
SPATA20 spermatogenesis associated 20 2.06107
PRR15L proline rich 15-like 2.06052
BRD4 bromodomain containing 4 2.0605
IGHMBP2 immunoglobulin mu binding protein 2 2.05949
PELO pelota homolog (Drosophila) 2.05906
CHPF2 chondroitin polymerizing factor 2 2.05808
STK17A serine/threonine kinase 17a 2.05633
CAVIN1 caveolae associated protein 1 2.05434
MECP2 methyl CpG binding protein 2 2.05421
CGB8 chorionic gonadotropin, beta polypeptide 8 2.05389
ROM1 retinal outer segment membrane protein 1 2.05286
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 2.05052
DNM2 dynamin 2 2.05037
MAN2C1 mannosidase, alpha, class 2C, member 1 2.04897
LOC124904942 uncharacterized LOC124904942 2.04564
KIFC3 kinesin family member C3 2.04524
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 2.04108
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 2.04035
FAM13A family with sequence similarity 13, member A 2.03741
TLK2 tousled-like kinase 2 2.03652
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 2.03546
HPSE heparanase 2.0348
TREH trehalase (brush-border membrane glycoprotein) 2.03467
BCL3 B-cell CLL/lymphoma 3 2.0294
FOXO4 forkhead box O4 2.0286
CD63 CD63 molecule 2.02682
BTG1 B-cell translocation gene 1, anti-proliferative 2.02668
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3 2.02659
ATF3 activating transcription factor 3 2.02593
ZNF589 zinc finger protein 589 2.02398
AMDHD2 amidohydrolase domain containing 2 2.02262
TRPM2 transient receptor potential cation channel, subfamily M, member 2 2.02069
HLX H2.0-like homeobox 2.01921
RCOR3 REST corepressor 3 2.01726
PLAUR plasminogen activator, urokinase receptor 2.01594
BCAS4 breast carcinoma amplified sequence 4 2.01566
IFNG interferon, gamma 2.0143
PCNX1 pecanex 1 2.01395
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 2.01346
SYNE2 spectrin repeat containing, nuclear envelope 2 2.01075
BPNT2 3'(2'), 5'-bisphosphate nucleotidase 2 2.0105
TRIM21 tripartite motif containing 21 2.00914
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 2.00734
MYF5 myogenic factor 5 2.00656
SFMBT1 Scm-like with four mbt domains 1 2.00603
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 2.00539
FBXO28 F-box protein 28 2.00412
CARD10 caspase recruitment domain family, member 10 2.00215
SLC43A3 solute carrier family 43, member 3 2.00102

decreased expression

Symbol Name Standardized Value
PCCB propionyl CoA carboxylase, beta polypeptide -9.66956
PROS1 protein S (alpha) -8.62128
FGFR4 fibroblast growth factor receptor 4 -8.43738
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -7.75803
ISOC1 isochorismatase domain containing 1 -7.67878
HMGA2 high mobility group AT-hook 2 -7.10622
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -7.00328
ADI1 acireductone dioxygenase 1 -6.98992
C5 complement component 5 -6.89148
LBR lamin B receptor -6.85954
RPIA ribose 5-phosphate isomerase A -6.84069
SLC35F2 solute carrier family 35, member F2 -6.61881
PGM1 phosphoglucomutase 1 -6.59135
CCNA2 cyclin A2 -6.55803
HEATR1 HEAT repeat containing 1 -6.44484
B4GAT1 beta-1,4-glucuronyltransferase 1 -6.30079
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -6.28077
MYC v-myc avian myelocytomatosis viral oncogene homolog -5.90148
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -5.8057
NIPSNAP1 nipsnap homolog 1 (C. elegans) -5.78552
PSRC1 proline/serine-rich coiled-coil 1 -5.75294
C2CD5 C2 calcium-dependent domain containing 5 -5.66393
CCNB2 cyclin B2 -5.50051
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -5.4658
PYCR1 pyrroline-5-carboxylate reductase 1 -5.32531
AURKB aurora kinase B -5.30176
PLK1 polo-like kinase 1 -5.29361
UBE2C ubiquitin-conjugating enzyme E2C -5.2089
TCTN1 tectonic family member 1 -5.20572
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -5.19985
RFC2 replication factor C (activator 1) 2, 40kDa -5.03313
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -4.9944
RPS5 ribosomal protein S5 -4.91637
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -4.87886
PHKB phosphorylase kinase, beta -4.85309
STMN1 stathmin 1 -4.72243
CDC20 cell division cycle 20 -4.71734
CDK1 cyclin-dependent kinase 1 -4.6889
HACD3 3-hydroxyacyl-CoA dehydratase 3 -4.68276
ENOPH1 enolase-phosphatase 1 -4.65214
TMEM109 transmembrane protein 109 -4.60882
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -4.5569
BLMH bleomycin hydrolase -4.50407
PECR peroxisomal trans-2-enoyl-CoA reductase -4.48264
USP6NL USP6 N-terminal like -4.44389
NUP93 nucleoporin 93kDa -4.35427
CCNB1 cyclin B1 -4.35386
PCNA proliferating cell nuclear antigen -4.33056
ANO10 anoctamin 10 -4.33053
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -4.31481
TRIB3 tribbles pseudokinase 3 -4.29018
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -4.24412
RPN1 ribophorin I -4.19648
ANXA7 annexin A7 -4.19461
RSU1 Ras suppressor protein 1 -4.19031
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -4.15637
SOAT2 sterol O-acyltransferase 2 -4.11898
DCK deoxycytidine kinase -4.10814
COG2 component of oligomeric golgi complex 2 -4.04725
CHEK2 checkpoint kinase 2 -4.02946
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -3.99304
ZDHHC6 zinc finger, DHHC-type containing 6 -3.94461
LDHD lactate dehydrogenase D -3.89676
UGDH UDP-glucose 6-dehydrogenase -3.89594
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -3.80996
FBXO5 F-box protein 5 -3.77243
ALDOC aldolase C, fructose-bisphosphate -3.7615
WDR7 WD repeat domain 7 -3.7165
WASF3 WAS protein family, member 3 -3.7042
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 -3.68047
AMBP alpha-1-microglobulin/bikunin precursor -3.63523
AHSG alpha-2-HS-glycoprotein -3.63486
HADH hydroxyacyl-CoA dehydrogenase -3.61374
CRYZ crystallin, zeta (quinone reductase) -3.60811
CDK4 cyclin-dependent kinase 4 -3.58582
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -3.58372
THAP11 THAP domain containing 11 -3.58243
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -3.5263
ASGR2 asialoglycoprotein receptor 2 -3.51594
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -3.484
CHMP6 charged multivesicular body protein 6 -3.47267
SCCPDH saccharopine dehydrogenase (putative) -3.47055
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -3.44685
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) -3.41507
FGA fibrinogen alpha chain -3.39684
AK4 adenylate kinase 4 -3.39462
AURKA aurora kinase A -3.37307
FGL1 fibrinogen-like 1 -3.36455
DENND2D DENN/MADD domain containing 2D -3.36115
SEH1L SEH1-like (S. cerevisiae) -3.3579
APOH apolipoprotein H (beta-2-glycoprotein I) -3.35537
MRPL12 mitochondrial ribosomal protein L12 -3.32491
GINS2 GINS complex subunit 2 (Psf2 homolog) -3.32286
DSCC1 DNA replication and sister chromatid cohesion 1 -3.31528
BIRC5 baculoviral IAP repeat containing 5 -3.31492
HMMR hyaluronan-mediated motility receptor (RHAMM) -3.30897
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 -3.28682
APOA2 apolipoprotein A-II -3.28662
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 -3.27524
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -3.26987
SAA4 serum amyloid A4, constitutive -3.26193
ERBB2 erb-b2 receptor tyrosine kinase 2 -3.25744
LAGE3 L antigen family, member 3 -3.24541
HDAC2 histone deacetylase 2 -3.22357
MELK maternal embryonic leucine zipper kinase -3.21923
SERP1 stress-associated endoplasmic reticulum protein 1 -3.21506
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) -3.20356
NR1H4 nuclear receptor subfamily 1, group H, member 4 -3.18714
FAT1 FAT atypical cadherin 1 -3.16983
METTL9 methyltransferase like 9 -3.16795
VDAC1 voltage-dependent anion channel 1 -3.14506
TIPRL TOR signaling pathway regulator -3.1408
HAT1 histone acetyltransferase 1 -3.13316
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 -3.12532
CPB2 carboxypeptidase B2 (plasma) -3.11647
PRR7 proline rich 7 (synaptic) -3.09907
GCSH glycine cleavage system protein H (aminomethyl carrier) -3.08467
NT5DC2 5'-nucleotidase domain containing 2 -3.08261
CAMKMT calmodulin-lysine N-methyltransferase -3.08142
DCTPP1 dCTP pyrophosphatase 1 -3.07824
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 -3.07103
KIF15 kinesin family member 15 -3.06444
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 -3.05198
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -3.04347
NFIL3 nuclear factor, interleukin 3 regulated -3.03022
PDIA6 protein disulfide isomerase family A, member 6 -3.02703
EIF5 eukaryotic translation initiation factor 5 -2.99624
CLIC4 chloride intracellular channel 4 -2.99127
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -2.98905
GLOD4 glyoxalase domain containing 4 -2.98755
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.98683
MYL9 myosin, light chain 9, regulatory -2.96016
MSRA methionine sulfoxide reductase A -2.9515
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -2.93814
AP1AR adaptor-related protein complex 1 associated regulatory protein -2.9324
RHOBTB1 Rho-related BTB domain containing 1 -2.93086
CRELD2 cysteine-rich with EGF-like domains 2 -2.92593
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -2.92206
SHCBP1 SHC SH2-domain binding protein 1 -2.91172
DHCR24 24-dehydrocholesterol reductase -2.90964
FBF1 Fas (TNFRSF6) binding factor 1 -2.90233
CANX calnexin -2.90212
TOP2A topoisomerase (DNA) II alpha 170kDa -2.90048
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.8896
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide -2.86503
MTFR1 mitochondrial fission regulator 1 -2.85686
ITGB5 integrin, beta 5 -2.84828
SCARB1 scavenger receptor class B, member 1 -2.84714
PIGR polymeric immunoglobulin receptor -2.84282
TMEM97 transmembrane protein 97 -2.84258
CNOT7 CCR4-NOT transcription complex, subunit 7 -2.84221
ITFG1 integrin alpha FG-GAP repeat containing 1 -2.83774
MAT2B methionine adenosyltransferase II, beta -2.83714
PXMP2 peroxisomal membrane protein 2, 22kDa -2.83642
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.83427
FGG fibrinogen gamma chain -2.82449
DDAH1 dimethylarginine dimethylaminohydrolase 1 -2.79235
HSPD1 heat shock 60kDa protein 1 (chaperonin) -2.78847
YME1L1 YME1-like 1 ATPase -2.78495
GPC3 glypican 3 -2.77954
FYN FYN proto-oncogene, Src family tyrosine kinase -2.77582
RABL3 RAB, member of RAS oncogene family-like 3 -2.76339
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -2.7615
LIMS2 LIM and senescent cell antigen-like domains 2 -2.76041
SLC66A2 solute carrier family 66 member 2 -2.75972
VRK1 vaccinia related kinase 1 -2.75932
GTF2A2 general transcription factor IIA, 2, 12kDa -2.75657
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -2.75302
REEP5 receptor accessory protein 5 -2.75272
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -2.73956
PM20D1 peptidase M20 domain containing 1 -2.73779
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.72261
ADAM10 ADAM metallopeptidase domain 10 -2.71456
KIF11 kinesin family member 11 -2.71275
INHBE inhibin, beta E -2.71012
TESC tescalcin -2.70606
ZMIZ1 zinc finger, MIZ-type containing 1 -2.70401
MRPS27 mitochondrial ribosomal protein S27 -2.69963
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -2.69288
SRPRB signal recognition particle receptor, B subunit -2.68921
PLSCR1 phospholipid scramblase 1 -2.68343
F9 coagulation factor IX -2.67589
RNF130 ring finger protein 130 -2.67588
LYPLA1 lysophospholipase I -2.67136
OXA1L oxidase (cytochrome c) assembly 1-like -2.66484
VTN vitronectin -2.66106
MRPL3 mitochondrial ribosomal protein L3 -2.6568
PTGES3 prostaglandin E synthase 3 (cytosolic) -2.65654
CWF19L1 CWF19-like 1, cell cycle control (S. pombe) -2.63964
PARP1 poly (ADP-ribose) polymerase 1 -2.63456
NHP2 NHP2 ribonucleoprotein -2.62485
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -2.61949
TYR tyrosinase -2.61741
AKR1D1 aldo-keto reductase family 1, member D1 -2.61448
NHLRC2 NHL repeat containing 2 -2.61362
C4BPA complement component 4 binding protein, alpha -2.6095
CHEK1 checkpoint kinase 1 -2.60882
MCM10 minichromosome maintenance complex component 10 -2.60845
SPDEF SAM pointed domain containing ETS transcription factor -2.60779
BANF1 barrier to autointegration factor 1 -2.60212
TMPO thymopoietin -2.60045
MAOB monoamine oxidase B -2.58231
RNASE4 ribonuclease, RNase A family, 4 -2.57551
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 -2.575
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 -2.57483
MAN1A1 mannosidase, alpha, class 1A, member 1 -2.57309
C8A complement component 8, alpha polypeptide -2.57306
SCD stearoyl-CoA desaturase (delta-9-desaturase) -2.57199
OIP5 Opa interacting protein 5 -2.564
GCA grancalcin, EF-hand calcium binding protein -2.56125
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 -2.55464
SNX5 sorting nexin 5 -2.55402
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) -2.55019
LRRC40 leucine rich repeat containing 40 -2.54808
ATF6 activating transcription factor 6 -2.54586
TOP2B topoisomerase (DNA) II beta 180kDa -2.54246
ANKRD46 ankyrin repeat domain 46 -2.54206
FNBP1L formin binding protein 1-like -2.54159
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 -2.53428
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -2.53067
ADH6 alcohol dehydrogenase 6 (class V) -2.524
MRPL19 mitochondrial ribosomal protein L19 -2.52013
HSPE1 heat shock 10kDa protein 1 -2.51965
GTPBP8 GTP-binding protein 8 (putative) -2.5171
DERA deoxyribose-phosphate aldolase (putative) -2.50362
MBL2 mannose-binding lectin (protein C) 2, soluble -2.50016
PRDX4 peroxiredoxin 4 -2.49275
ELAVL1 ELAV like RNA binding protein 1 -2.48594
SDF2L1 stromal cell-derived factor 2-like 1 -2.4781
GOLPH3L golgi phosphoprotein 3-like -2.47389
LOC124907782 dual specificity protein phosphatase 22 -2.4654
SLC17A2 solute carrier family 17, member 2 -2.46012
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -2.45732
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 -2.4567
MRPL44 mitochondrial ribosomal protein L44 -2.45223
DHFR dihydrofolate reductase -2.44989
NOL11 nucleolar protein 11 -2.44904
HIBCH 3-hydroxyisobutyryl-CoA hydrolase -2.44772
ISOC2 isochorismatase domain containing 2 -2.44533
EML4 echinoderm microtubule associated protein like 4 -2.44531
PPP4C protein phosphatase 4, catalytic subunit -2.44154
TIMCC TIM double twin CX3C motif chaperone -2.43956
MSH2 mutS homolog 2 -2.43531
A2M alpha-2-macroglobulin -2.4351
FGB fibrinogen beta chain -2.43453
MORF4L2 mortality factor 4 like 2 -2.43173
HPR haptoglobin-related protein -2.41733
IDI1 isopentenyl-diphosphate delta isomerase 1 -2.41524
PTPRK protein tyrosine phosphatase, receptor type, K -2.41054
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -2.40615
C8B complement component 8, beta polypeptide -2.4048
SATB1 SATB homeobox 1 -2.39985
EBAG9 estrogen receptor binding site associated, antigen, 9 -2.39816
STIL SCL/TAL1 interrupting locus -2.38748
AUNIP aurora kinase A and ninein interacting protein -2.3845
NANS N-acetylneuraminic acid synthase -2.38223
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -2.38181
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -2.3814
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase -2.36931
TMED5 transmembrane emp24 protein transport domain containing 5 -2.36812
PEBP1 phosphatidylethanolamine binding protein 1 -2.36575
NTAQ1 N-terminal glutamine amidase 1 -2.36317
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta -2.36133
FHIT fragile histidine triad -2.35628
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) -2.35262
RBBP4 retinoblastoma binding protein 4 -2.34838
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -2.34274
ANG angiogenin, ribonuclease, RNase A family, 5 -2.33829
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 -2.3375
TTF2 transcription termination factor, RNA polymerase II -2.33561
COMMD10 COMM domain containing 10 -2.33396
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.33172
TMA16 translation machinery associated 16 homolog (S. cerevisiae) -2.33084
HEATR3 HEAT repeat containing 3 -2.32469
PARG poly (ADP-ribose) glycohydrolase -2.32206
WASHC5 WASH complex subunit 5 -2.31978
DPYD dihydropyrimidine dehydrogenase -2.31954
TM9SF2 transmembrane 9 superfamily member 2 -2.3188
RIDA reactive intermediate imine deaminase A homolog -2.31875
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -2.31156
GNAS GNAS complex locus -2.31057
ORC6 origin recognition complex, subunit 6 -2.30736
ORM2 orosomucoid 2 -2.30292
CD5L CD5 molecule-like -2.30282
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum) -2.30212
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.29932
CENPA centromere protein A -2.29483
COMMD9 COMM domain containing 9 -2.2934
VIPR1 vasoactive intestinal peptide receptor 1 -2.29017
MYH10 myosin, heavy chain 10, non-muscle -2.28579
NCAPH non-SMC condensin I complex, subunit H -2.2857
TBC1D8B TBC1 domain family, member 8B (with GRAM domain) -2.28295
AGMAT agmatine ureohydrolase (agmatinase) -2.2797
MPC1 mitochondrial pyruvate carrier 1 -2.27862
WDR18 WD repeat domain 18 -2.27282
TRAPPC3 trafficking protein particle complex 3 -2.27117
ATP5F1C ATP synthase F1 subunit gamma -2.26708
STX8 syntaxin 8 -2.26505
HBG1 hemoglobin, gamma A -2.26491
APOC1 apolipoprotein C-I -2.26248
EHBP1 EH domain binding protein 1 -2.25781
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -2.25192
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 -2.25089
VCAM1 vascular cell adhesion molecule 1 -2.24886
SORT1 sortilin 1 -2.24815
ASGR1 asialoglycoprotein receptor 1 -2.24065
EXTL2 exostosin-like glycosyltransferase 2 -2.23528
KIF4A kinesin family member 4A -2.23293
RHOT1 ras homolog family member T1 -2.22881
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 -2.2265
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -2.22469
LCMT1 leucine carboxyl methyltransferase 1 -2.2239
THEM6 thioesterase superfamily member 6 -2.2197
ANO3 anoctamin 3 -2.21499
NUP43 nucleoporin 43kDa -2.21425
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -2.20965
MSMO1 methylsterol monooxygenase 1 -2.20788
MSH6 mutS homolog 6 -2.2073
PCM1 pericentriolar material 1 -2.20617
PAH phenylalanine hydroxylase -2.2059
SERBP1 SERPINE1 mRNA binding protein 1 -2.20575
TMED2 transmembrane emp24 domain trafficking protein 2 -2.20499
DCP2 decapping mRNA 2 -2.20333
ITGA8 integrin, alpha 8 -2.20277
RAB3IL1 RAB3A interacting protein (rabin3)-like 1 -2.19792
HSPA14 heat shock 70kDa protein 14 -2.19715
GPHN gephyrin -2.19608
BEX2 brain expressed X-linked 2 -2.19445
DPYS dihydropyrimidinase -2.19324
DBF4 DBF4 zinc finger -2.19054
TMEM243 transmembrane protein 243, mitochondrial -2.18997
GDI2 GDP dissociation inhibitor 2 -2.18977
SFXN1 sideroflexin 1 -2.18825
HEBP1 heme binding protein 1 -2.18789
TMX1 thioredoxin-related transmembrane protein 1 -2.18669
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 -2.18642
TRAK2 trafficking protein, kinesin binding 2 -2.17568
UNC13B unc-13 homolog B (C. elegans) -2.17517
CCNC cyclin C -2.17407
CELF2 CUGBP, Elav-like family member 2 -2.17124
DARS2 aspartyl-tRNA synthetase 2, mitochondrial -2.17087
F7 coagulation factor VII (serum prothrombin conversion accelerator) -2.17054
MCM6 minichromosome maintenance complex component 6 -2.1692
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.1682
STX7 syntaxin 7 -2.16706
HAMP hepcidin antimicrobial peptide -2.15787
ALDH18A1 aldehyde dehydrogenase 18 family, member A1 -2.15144
MRPL35 mitochondrial ribosomal protein L35 -2.14999
NME1 NME/NM23 nucleoside diphosphate kinase 1 -2.14402
ATP5F1A ATP synthase F1 subunit alpha -2.14189
U2SURP U2 snRNP-associated SURP domain containing -2.14119
SKA1 spindle and kinetochore associated complex subunit 1 -2.13699
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta -2.13672
HMG20B high mobility group 20B -2.1361
VTI1B vesicle transport through interaction with t-SNAREs 1B -2.13574
MAT1A methionine adenosyltransferase I, alpha -2.13149
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 -2.13115
PGAM4 phosphoglycerate mutase family member 4 -2.13114
UXT ubiquitously-expressed, prefoldin-like chaperone -2.13088
SLC45A2 solute carrier family 45, member 2 -2.13016
MRPL37 mitochondrial ribosomal protein L37 -2.12651
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -2.12477
EIF3CL eukaryotic translation initiation factor 3, subunit C-like -2.12444
SEPHS2 selenophosphate synthetase 2 -2.12238
NUP133 nucleoporin 133kDa -2.11719
UQCRC2 ubiquinol-cytochrome c reductase core protein II -2.1157
MPZL1 myelin protein zero-like 1 -2.11497
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 -2.11225
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -2.11195
TTK TTK protein kinase -2.11133
GFUS GDP-L-fucose synthase -2.10782
SPC25 SPC25, NDC80 kinetochore complex component -2.10736
UNC50 unc-50 homolog (C. elegans) -2.1073
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.10554
CHMP4B charged multivesicular body protein 4B -2.10114
IGFBP1 insulin-like growth factor binding protein 1 -2.10023
LYZ lysozyme -2.09823
RLIG1 RNA 5'-phosphate and 3'-OH ligase 1 -2.09781
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 -2.09605
CDC73 cell division cycle 73 -2.09552
E2F8 E2F transcription factor 8 -2.08981
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) -2.08681
APOC3 apolipoprotein C-III -2.08514
ICAM3 intercellular adhesion molecule 3 -2.08439
FKBP3 FK506 binding protein 3, 25kDa -2.08103
DUT deoxyuridine triphosphatase -2.07853
ENTR1 endosome associated trafficking regulator 1 -2.07576
ZFP30 ZFP30 zinc finger protein -2.0756
C4A complement component 4A (Rodgers blood group) -2.07401
ERBB3 erb-b2 receptor tyrosine kinase 3 -2.07261
HPX hemopexin -2.06645
MRPS2 mitochondrial ribosomal protein S2 -2.06632
SGF29 SAGA complex associated factor 29 -2.06539
CNN3 calponin 3, acidic -2.06199
TMEM50A transmembrane protein 50A -2.06158
ANGPTL8 angiopoietin like 8 -2.0592
HMOX1 heme oxygenase 1 -2.05762
UNG uracil-DNA glycosylase -2.05476
DBR1 debranching RNA lariats 1 -2.0532
TXNL4A thioredoxin-like 4A -2.05043
RENBP renin binding protein -2.05035
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 -2.04989
UGP2 UDP-glucose pyrophosphorylase 2 -2.04808
LRRC8D leucine rich repeat containing 8 family, member D -2.04468
SEPTIN11 septin 11 -2.04338
RGS7 regulator of G-protein signaling 7 -2.03982
FBXO11 F-box protein 11 -2.03948
STXBP2 syntaxin binding protein 2 -2.03911
ECT2 epithelial cell transforming 2 -2.03859
RBMX RNA binding motif protein, X-linked -2.03746
TOMM70 translocase of outer mitochondrial membrane 70 -2.0373
TXNL1 thioredoxin-like 1 -2.03668
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -2.03529
IQGAP2 IQ motif containing GTPase activating protein 2 -2.03375
ZNF816 zinc finger protein 816 -2.03295
ATP13A3 ATPase type 13A3 -2.03256
BARX2 BARX homeobox 2 -2.03242
PHB1 prohibitin 1 -2.03196
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 -2.03159
CYB5B cytochrome b5 type B (outer mitochondrial membrane) -2.03089
PGK1 phosphoglycerate kinase 1 -2.02539
CLIC3 chloride intracellular channel 3 -2.0219
ALDH1B1 aldehyde dehydrogenase 1 family, member B1 -2.01786
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 -2.01712
CFI complement factor I -2.01615
CDC23 cell division cycle 23 -2.01493
GJB1 gap junction protein, beta 1, 32kDa -2.01444
TEX2 testis expressed 2 -2.0143
CNIH1 cornichon family AMPA receptor auxiliary protein 1 -2.01041
CFHR2 complement factor H-related 2 -2.01029
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 -2.00999
KCTD20 potassium channel tetramerization domain containing 20 -2.00978
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -2.0084
ARMC8 armadillo repeat containing 8 -2.00695
IMPACT impact RWD domain protein -2.00558