CRCGN013_HEPG2_24H:K03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description o-phenylenediamine.2hcl 10.2 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

992 genes differentially expressed following the CRCGN013_HEPG2_24H:K03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CDPF1 cysteine-rich, DPF motif domain containing 1 10.0
BLCAP bladder cancer associated protein 9.30532
ABHD4 abhydrolase domain containing 4 9.24241
INPP1 inositol polyphosphate-1-phosphatase 9.12554
CNPY3 canopy FGF signaling regulator 3 9.09638
CCDC92 coiled-coil domain containing 92 9.06819
DDB2 damage-specific DNA binding protein 2, 48kDa 8.41241
MICALL1 MICAL-like 1 7.69349
TUBB6 tubulin, beta 6 class V 7.61751
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 7.42777
LRP10 low density lipoprotein receptor-related protein 10 7.12369
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 6.91623
DUSP14 dual specificity phosphatase 14 6.52835
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 6.48455
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 6.42329
NR1H2 nuclear receptor subfamily 1, group H, member 2 6.34249
KIFBP kinesin family binding protein 6.1882
PPARG peroxisome proliferator-activated receptor gamma 6.06199
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 6.0471
GPC1 glypican 1 5.97754
IL4R interleukin 4 receptor 5.86988
MCOLN1 mucolipin 1 5.77236
MINDY1 MINDY lysine 48 deubiquitinase 1 5.6708
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 5.62702
TXNRD1 thioredoxin reductase 1 5.47447
KHDC4 KH domain containing 4, pre-mRNA splicing factor 5.45924
KEAP1 kelch-like ECH-associated protein 1 5.42987
STX1A syntaxin 1A (brain) 5.42136
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 5.36281
TESK1 testis-specific kinase 1 5.35005
LSR lipolysis stimulated lipoprotein receptor 5.27893
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 5.27224
CASC3 cancer susceptibility candidate 3 4.99265
GADD45A growth arrest and DNA-damage-inducible, alpha 4.96381
KDM5A lysine (K)-specific demethylase 5A 4.96027
TIMP2 TIMP metallopeptidase inhibitor 2 4.95291
KLHL21 kelch-like family member 21 4.89479
CGRRF1 cell growth regulator with ring finger domain 1 4.82955
TOR1A torsin family 1, member A (torsin A) 4.75828
ANKRD10 ankyrin repeat domain 10 4.7296
TERF2IP telomeric repeat binding factor 2, interacting protein 4.71702
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 4.70543
GATA3 GATA binding protein 3 4.70413
ADGRE5 adhesion G protein-coupled receptor E5 4.48242
FOXJ3 forkhead box J3 4.48166
PRKCQ protein kinase C, theta 4.47731
IGFBP3 insulin-like growth factor binding protein 3 4.39168
FOSL1 FOS-like antigen 1 4.38612
FOS FBJ murine osteosarcoma viral oncogene homolog 4.265
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 4.20899
IGHMBP2 immunoglobulin mu binding protein 2 4.17112
SNAP25 synaptosomal-associated protein, 25kDa 4.13045
PRKCH protein kinase C, eta 4.09763
SKIC2 SKI2 subunit of superkiller complex 4.09726
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 4.07668
PRAF2 PRA1 domain family, member 2 4.04147
GPER1 G protein-coupled estrogen receptor 1 3.9786
DGKA diacylglycerol kinase, alpha 80kDa 3.89478
PLK3 polo-like kinase 3 3.88992
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 3.86441
ADGRG1 adhesion G protein-coupled receptor G1 3.84904
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 3.83799
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 3.8161
PRKCD protein kinase C, delta 3.81559
H2BC21 H2B clustered histone 21 3.79458
DDR1 discoidin domain receptor tyrosine kinase 1 3.77498
ALAS1 5'-aminolevulinate synthase 1 3.75683
C2CD2 C2 calcium-dependent domain containing 2 3.74403
OFD1 oral-facial-digital syndrome 1 3.7276
MAP7D1 MAP7 domain containing 1 3.6755
CCL2 chemokine (C-C motif) ligand 2 3.64847
PHLDA3 pleckstrin homology-like domain, family A, member 3 3.62548
HBEGF heparin-binding EGF-like growth factor 3.60824
NIT1 nitrilase 1 3.5923
IL17RA interleukin 17 receptor A 3.57072
HLA-DRA major histocompatibility complex, class II, DR alpha 3.54802
CAMTA2 calmodulin binding transcription activator 2 3.53274
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 3.52985
ULK1 unc-51 like autophagy activating kinase 1 3.52841
GPR87 G protein-coupled receptor 87 3.50828
OSGIN1 oxidative stress induced growth inhibitor 1 3.49388
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 3.47418
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 3.46769
NISCH nischarin 3.45621
ADO 2-aminoethanethiol (cysteamine) dioxygenase 3.45558
ANGPTL4 angiopoietin-like 4 3.4266
MVP major vault protein 3.41252
PIGG phosphatidylinositol glycan anchor biosynthesis, class G 3.39129
HCFC2 host cell factor C2 3.39107
ERCC5 excision repair cross-complementation group 5 3.33992
TREM1 triggering receptor expressed on myeloid cells 1 3.31967
TOB1 transducer of ERBB2, 1 3.31932
DUSP6 dual specificity phosphatase 6 3.31382
LRRC41 leucine rich repeat containing 41 3.31166
SCPEP1 serine carboxypeptidase 1 3.30343
ATP11B ATPase, class VI, type 11B 3.30139
SRC SRC proto-oncogene, non-receptor tyrosine kinase 3.29129
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 3.28047
PRR15L proline rich 15-like 3.25477
PNKP polynucleotide kinase 3'-phosphatase 3.24462
CXCL2 chemokine (C-X-C motif) ligand 2 3.22891
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 3.19219
PI4KB phosphatidylinositol 4-kinase, catalytic, beta 3.19111
MAD2L1BP MAD2L1 binding protein 3.18997
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 3.16025
TSPYL2 TSPY-like 2 3.14447
RALB v-ral simian leukemia viral oncogene homolog B 3.14012
ATG9A autophagy related 9A 3.13969
KDM3A lysine (K)-specific demethylase 3A 3.13108
SMAD3 SMAD family member 3 3.12168
XPC xeroderma pigmentosum, complementation group C 3.12027
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 3.09992
PHF1 PHD finger protein 1 3.09498
IL11 interleukin 11 3.09005
TIGAR TP53 induced glycolysis regulatory phosphatase 3.07718
CTSL cathepsin L 3.05974
SQOR sulfide quinone oxidoreductase 3.05867
DHRS7 dehydrogenase/reductase (SDR family) member 7 3.05741
SPATA20 spermatogenesis associated 20 3.05732
COL17A1 collagen, type XVII, alpha 1 3.05398
PPIE peptidylprolyl isomerase E (cyclophilin E) 3.02858
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 3.02543
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 3.02166
PRPF3 pre-mRNA processing factor 3 3.01925
GABARAPL1 GABA(A) receptor-associated protein like 1 3.01572
RAP1GAP RAP1 GTPase activating protein 3.01482
ZNF222 zinc finger protein 222 3.00392
TCF15 transcription factor 15 (basic helix-loop-helix) 2.99623
PTHLH parathyroid hormone-like hormone 2.99459
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 2.99085
THSD1 thrombospondin, type I, domain containing 1 2.9842
GNL1 guanine nucleotide binding protein-like 1 2.97656
ASCC3 activating signal cointegrator 1 complex subunit 3 2.975
PLPP1 phospholipid phosphatase 1 2.96337
PLCH2 phospholipase C, eta 2 2.9607
NME8 NME/NM23 family member 8 2.94405
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase 2.94164
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 2.93821
GSDME gasdermin E 2.93144
ELAC2 elaC ribonuclease Z 2 2.92959
CCNL1 cyclin L1 2.92941
HLX H2.0-like homeobox 2.92832
TXLNA taxilin alpha 2.91674
TDP2 tyrosyl-DNA phosphodiesterase 2 2.91343
KANSL2 KAT8 regulatory NSL complex subunit 2 2.91321
TOMM34 translocase of outer mitochondrial membrane 34 2.90912
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated 2.90504
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.89803
KLHL36 kelch-like family member 36 2.89016
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5 2.88024
RFX5 regulatory factor X, 5 (influences HLA class II expression) 2.87807
GJB5 gap junction protein, beta 5, 31.1kDa 2.87645
RCOR3 REST corepressor 3 2.87201
ZBTB48 zinc finger and BTB domain containing 48 2.8704
ZNF45 zinc finger protein 45 2.86217
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 2.86046
ZNF212 zinc finger protein 212 2.85938
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 2.85678
RAB11FIP1 RAB11 family interacting protein 1 (class I) 2.84729
ZNF226 zinc finger protein 226 2.8361
CSNK1E casein kinase 1, epsilon 2.82683
PRSS16 protease, serine, 16 (thymus) 2.81928
HSPB3 heat shock 27kDa protein 3 2.81555
MOK MOK protein kinase 2.81325
ZNF282 zinc finger protein 282 2.81189
FASTKD5 FAST kinase domains 5 2.81012
ELF4 E74-like factor 4 (ets domain transcription factor) 2.809
ST18 suppression of tumorigenicity 18, zinc finger 2.79537
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 2.79294
E2F2 E2F transcription factor 2 2.79198
TBX3 T-box 3 2.78902
TP53I3 tumor protein p53 inducible protein 3 2.78845
STX4 syntaxin 4 2.78794
UBAP1 ubiquitin associated protein 1 2.78571
ZXDC ZXD family zinc finger C 2.78129
MTCH1 mitochondrial carrier 1 2.77595
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) 2.77169
NALF2 NALCN channel auxiliary factor 2 2.77015
CSF3 colony stimulating factor 3 (granulocyte) 2.76854
VAT1 vesicle amine transport 1 2.76792
ZNF219 zinc finger protein 219 2.76784
ZNF79 zinc finger protein 79 2.75568
CCNL2 cyclin L2 2.75132
AGAP4 ArfGAP with GTPase domain, ankyrin repeat and PH domain 4 2.75017
IQCC IQ motif containing C 2.74678
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 2.74329
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 2.74246
KCNMB1 potassium channel subfamily M regulatory beta subunit 1 2.74149
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 2.73223
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2.73023
NOTCH1 notch 1 2.72704
SIRT7 sirtuin 7 2.72268
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 2.7217
LAMC2 laminin, gamma 2 2.71776
YPEL5 yippee-like 5 (Drosophila) 2.71416
RNF25 ring finger protein 25 2.70937
LOC124904942 uncharacterized LOC124904942 2.70341
COL4A6 collagen, type IV, alpha 6 2.69391
IER3 immediate early response 3 2.69176
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 2.69168
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.68699
HOXA1 homeobox A1 2.68504
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) 2.68074
ZNF195 zinc finger protein 195 2.6772
INPP5K inositol polyphosphate-5-phosphatase K 2.66553
LDOC1 leucine zipper, down-regulated in cancer 1 2.66286
PORCN porcupine homolog (Drosophila) 2.65828
DMTF1 cyclin D binding myb-like transcription factor 1 2.65489
TM4SF20 transmembrane 4 L six family member 20 2.65406
SV2A synaptic vesicle glycoprotein 2A 2.6461
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 2.63555
PHC1 polyhomeotic homolog 1 (Drosophila) 2.62863
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 2.61802
GDAP1L1 ganglioside induced differentiation associated protein 1-like 1 2.61728
RSF1 remodeling and spacing factor 1 2.6162
PHKG2 phosphorylase kinase, gamma 2 (testis) 2.61578
NPDC1 neural proliferation, differentiation and control, 1 2.61128
PLEC plectin 2.60648
SYNM synemin, intermediate filament protein 2.60306
MEF2D myocyte enhancer factor 2D 2.59985
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C 2.5924
NBR1 neighbor of BRCA1 gene 1 2.59083
GPATCH3 G patch domain containing 3 2.59082
ROM1 retinal outer segment membrane protein 1 2.57153
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 2.56592
MPPE1 metallophosphoesterase 1 2.54845
KRT7 keratin 7, type II 2.54747
YIPF3 Yip1 domain family, member 3 2.54013
TBKBP1 TBK1 binding protein 1 2.53842
KCNK1 potassium channel, two pore domain subfamily K, member 1 2.53558
ZBED5 zinc finger, BED-type containing 5 2.53522
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 2.53507
NFRKB nuclear factor related to kappaB binding protein 2.53497
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 2.53154
ELMO3 engulfment and cell motility 3 2.52998
PICK1 protein interacting with PRKCA 1 2.5286
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 2.52667
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 2.52444
PROCR protein C receptor, endothelial 2.52317
ZDHHC24 zinc finger, DHHC-type containing 24 2.52179
CLK3 CDC-like kinase 3 2.52042
SSBP2 single-stranded DNA binding protein 2 2.52032
FAM193A family with sequence similarity 193, member A 2.52029
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 2.51704
SFTPB surfactant protein B 2.51426
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14 2.51183
THUMPD2 THUMP domain containing 2 2.51068
CBX6 chromobox homolog 6 2.50766
MON1B MON1 secretory trafficking family member B 2.50739
TOE1 target of EGR1, member 1 (nuclear) 2.50237
SESN1 sestrin 1 2.50234
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 2.50132
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 2.49842
DYNLT3 dynein, light chain, Tctex-type 3 2.49842
FUZ fuzzy planar cell polarity protein 2.49806
ARID5A AT rich interactive domain 5A (MRF1-like) 2.4967
TCP11L1 t-complex 11, testis-specific-like 1 2.49602
ZFHX3 zinc finger homeobox 3 2.49513
PI4K2A phosphatidylinositol 4-kinase type 2 alpha 2.49411
SRSF4 serine/arginine-rich splicing factor 4 2.49364
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae) 2.49347
GRN granulin 2.48893
LAMB3 laminin, beta 3 2.48798
CSRNP2 cysteine-serine-rich nuclear protein 2 2.48497
PANK4 pantothenate kinase 4 2.4791
STK17A serine/threonine kinase 17a 2.47873
CDK11A cyclin-dependent kinase 11A 2.47654
FAM246A family with sequence similarity 246 member A 2.47073
ADRB2 adrenoceptor beta 2, surface 2.46416
ZSCAN26 zinc finger and SCAN domain containing 26 2.46406
ATP10D ATPase, class V, type 10D 2.46284
HOXA10 homeobox A10 2.46274
GCLC glutamate-cysteine ligase, catalytic subunit 2.46223
TLR3 toll-like receptor 3 2.4577
PXDC1 PX domain containing 1 2.45515
TRIM11 tripartite motif containing 11 2.45265
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein 2.45209
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit 2.44973
DGKG diacylglycerol kinase, gamma 90kDa 2.44912
IL13RA2 interleukin 13 receptor, alpha 2 2.44764
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) 2.44019
UST uronyl-2-sulfotransferase 2.43211
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 2.43179
TLE3 transducin-like enhancer of split 3 2.43138
SYNRG synergin, gamma 2.42596
ELAVL3 ELAV like neuron-specific RNA binding protein 3 2.42589
CHRDL1 chordin-like 1 2.4253
ZNF862 zinc finger protein 862 2.42314
ZNF224 zinc finger protein 224 2.41881
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 2.41697
TBC1D19 TBC1 domain family, member 19 2.41583
KLHL20 kelch-like family member 20 2.41271
FHIP2B FHF complex subunit HOOK interacting protein 2B 2.40533
CSNK1G1 casein kinase 1, gamma 1 2.40363
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 2.40245
CCDC90B coiled-coil domain containing 90B 2.401
CDIP1 cell death-inducing p53 target 1 2.39929
PNKD paroxysmal nonkinesigenic dyskinesia 2.3985
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11 2.39768
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 2.3948
PTCD2 pentatricopeptide repeat domain 2 2.38782
UBE2H ubiquitin-conjugating enzyme E2H 2.3848
SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) 2.38327
SH2D2A SH2 domain containing 2A 2.37799
MBOAT7 membrane bound O-acyltransferase domain containing 7 2.37754
REEP2 receptor accessory protein 2 2.37456
PTPN7 protein tyrosine phosphatase, non-receptor type 7 2.37421
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 2.37
LMOD1 leiomodin 1 (smooth muscle) 2.36732
DUSP3 dual specificity phosphatase 3 2.36677
FOXF2 forkhead box F2 2.36661
ATG2A autophagy related 2A 2.36513
CD1B CD1b molecule 2.36019
RGS2 regulator of G-protein signaling 2 2.3595
TSC22D3 TSC22 domain family, member 3 2.35582
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) 2.35237
TRIM8 tripartite motif containing 8 2.34955
APH1B APH1B gamma secretase subunit 2.34759
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 2.34599
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit 2.34447
FOXD1 forkhead box D1 2.34213
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 2.34174
TMEM115 transmembrane protein 115 2.33769
PNMA3 paraneoplastic Ma antigen 3 2.3366
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 2.32487
STARD3 StAR-related lipid transfer (START) domain containing 3 2.32391
RIOK3 RIO kinase 3 2.32299
ZNF532 zinc finger protein 532 2.3216
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae) 2.31951
FSTL3 follistatin-like 3 (secreted glycoprotein) 2.31926
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 2.31865
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 2.31498
KMT5A lysine methyltransferase 5A 2.31379
AEN apoptosis enhancing nuclease 2.30881
OTULINL OTU deubiquitinase with linear linkage specificity like 2.30812
JPH2 junctophilin 2 2.30498
SUN2 Sad1 and UNC84 domain containing 2 2.30334
SOX15 SRY (sex determining region Y)-box 15 2.30023
TREM2 triggering receptor expressed on myeloid cells 2 2.29948
ODR4 odr-4 GPCR localization factor homolog 2.29945
TMUB2 transmembrane and ubiquitin-like domain containing 2 2.29864
STOM stomatin 2.29838
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 2.29414
TNFAIP8L2-SCNM1 TNFAIP8L2-SCNM1 readthrough 2.29365
LGMN legumain 2.29314
FLNC filamin C, gamma 2.29246
UIMC1 ubiquitin interaction motif containing 1 2.29177
OVCA2 ovarian tumor suppressor candidate 2 2.29111
TACR2 tachykinin receptor 2 2.29095
TGFBI transforming growth factor, beta-induced, 68kDa 2.28977
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 2.28222
SLC30A1 solute carrier family 30 (zinc transporter), member 1 2.28105
PTCRA pre T-cell antigen receptor alpha 2.27895
GSDMB gasdermin B 2.27828
PIGB phosphatidylinositol glycan anchor biosynthesis, class B 2.27066
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 2.27014
DMPK dystrophia myotonica-protein kinase 2.26781
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 2.26313
PRKD2 protein kinase D2 2.26011
RBM41 RNA binding motif protein 41 2.25886
RGPD1 RANBP2-like and GRIP domain containing 1 2.25562
ZNF467 zinc finger protein 467 2.25425
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 2.25365
BAX BCL2-associated X protein 2.25253
ZNF75D zinc finger protein 75D 2.24727
IRF5 interferon regulatory factor 5 2.24514
NOP2 NOP2 nucleolar protein 2.24322
ZNF638 zinc finger protein 638 2.23871
CIC capicua transcriptional repressor 2.23808
ZNF669 zinc finger protein 669 2.2345
SPAG9 sperm associated antigen 9 2.23117
ELMO2 engulfment and cell motility 2 2.22778
SNX13 sorting nexin 13 2.22296
PPP1R17 protein phosphatase 1, regulatory subunit 17 2.22158
SQSTM1 sequestosome 1 2.21724
RIN1 Ras and Rab interactor 1 2.21722
RAP1GAP2 RAP1 GTPase activating protein 2 2.21696
KLC3 kinesin light chain 3 2.21557
CYTH2 cytohesin 2 2.21504
ASB7 ankyrin repeat and SOCS box containing 7 2.20985
SMIM40 small integral membrane protein 40 2.20894
RAB11FIP2 RAB11 family interacting protein 2 (class I) 2.20768
KDM6B lysine (K)-specific demethylase 6B 2.20747
PRICKLE3 prickle homolog 3 (Drosophila) 2.20715
EYA1 EYA transcriptional coactivator and phosphatase 1 2.20355
ZNF225 zinc finger protein 225 2.20331
YY1AP1 YY1 associated protein 1 2.20303
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 2.20113
KDM5C lysine (K)-specific demethylase 5C 2.20068
LMO3 LIM domain only 3 (rhombotin-like 2) 2.20009
REG1B regenerating islet-derived 1 beta 2.1976
IP6K2 inositol hexakisphosphate kinase 2 2.19067
KCTD9 potassium channel tetramerization domain containing 9 2.19041
TUT7 terminal uridylyl transferase 7 2.18804
PLD2 phospholipase D2 2.18722
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 2.18603
CREB3L4 cAMP responsive element binding protein 3-like 4 2.18547
ZNF384 zinc finger protein 384 2.18025
ZNF432 zinc finger protein 432 2.17884
CALCOCO1 calcium binding and coiled-coil domain 1 2.17265
MYOF myoferlin 2.1697
EIF6 eukaryotic translation initiation factor 6 2.16959
TIAM1 T-cell lymphoma invasion and metastasis 1 2.16723
GBP2 guanylate binding protein 2, interferon-inducible 2.16553
GPN2 GPN-loop GTPase 2 2.16538
NOX5 NADPH oxidase, EF-hand calcium binding domain 5 2.16482
TBC1D31 TBC1 domain family, member 31 2.15844
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 2.15439
RPRD2 regulation of nuclear pre-mRNA domain containing 2 2.15169
MACO1 macoilin 1 2.15166
IQSEC2 IQ motif and Sec7 domain 2 2.1494
CNPY4 canopy FGF signaling regulator 4 2.14884
GOLGA8F golgin A8 family, member F 2.14826
PACSIN1 protein kinase C and casein kinase substrate in neurons 1 2.14458
KMT5B lysine methyltransferase 5B 2.14364
MOGAT1 monoacylglycerol O-acyltransferase 1 2.1428
MICALL2 MICAL-like 2 2.1424
ERVMER34-1 endogenous retrovirus group MER34, member 1 2.1383
BBC3 BCL2 binding component 3 2.13817
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 2.13574
ADAM15 ADAM metallopeptidase domain 15 2.13455
ZFTRAF1 zinc finger TRAF-type containing 1 2.13334
MUC13 mucin 13, cell surface associated 2.1332
SOX30 SRY (sex determining region Y)-box 30 2.13253
TMEM94 transmembrane protein 94 2.13238
PHTF1 putative homeodomain transcription factor 1 2.13226
ITCH itchy E3 ubiquitin protein ligase 2.13209
MEA1 male-enhanced antigen 1 2.1296
TBCC tubulin folding cofactor C 2.12763
ZNF574 zinc finger protein 574 2.12719
UNC119B unc-119 homolog B (C. elegans) 2.12707
PTPN6 protein tyrosine phosphatase, non-receptor type 6 2.1264
WDR6 WD repeat domain 6 2.12604
KIAA0232 KIAA0232 2.12522
ULBP2 UL16 binding protein 2 2.12479
BAD BCL2-associated agonist of cell death 2.12443
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 2.12411
ZNF557 zinc finger protein 557 2.12409
KLRC3 killer cell lectin-like receptor subfamily C, member 3 2.1234
IL1A interleukin 1, alpha 2.12119
S100A11 S100 calcium binding protein A11 2.11907
SEC31B SEC31 homolog B (S. cerevisiae) 2.11858
BECN1 beclin 1, autophagy related 2.11759
MBD1 methyl-CpG binding domain protein 1 2.11638
XDH xanthine dehydrogenase 2.11614
SSH3 slingshot protein phosphatase 3 2.11541
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 2.11295
CTF1 cardiotrophin 1 2.1128
OPRD1 opioid receptor, delta 1 2.11192
PARP8 poly (ADP-ribose) polymerase family, member 8 2.11023
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) 2.10977
FAM53C family with sequence similarity 53, member C 2.10956
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 2.10873
RANBP3 RAN binding protein 3 2.10659
NDRG1 N-myc downstream regulated 1 2.10563
LUZP1 leucine zipper protein 1 2.10407
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 2.1018
SLC16A4 solute carrier family 16, member 4 2.10138
MTMR6 myotubularin related protein 6 2.10134
H2AC6 H2A clustered histone 6 2.09797
ZNF227 zinc finger protein 227 2.09793
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.09687
HSPB8 heat shock 22kDa protein 8 2.09537
ZNF223 zinc finger protein 223 2.09534
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 2.09425
ZNF646 zinc finger protein 646 2.09395
CDKN2AIP CDKN2A interacting protein 2.09332
MAPK12 mitogen-activated protein kinase 12 2.0931
PCNX1 pecanex 1 2.09203
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 2.09035
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa 2.08974
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 2.08949
FERRY3 FERRY endosomal RAB5 effector complex subunit 3 2.08902
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 2.08788
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) 2.08559
ZNF444 zinc finger protein 444 2.08545
SAFB2 scaffold attachment factor B2 2.08279
SLCO3A1 solute carrier organic anion transporter family, member 3A1 2.08148
THBS3 thrombospondin 3 2.08134
MXD4 MAX dimerization protein 4 2.08067
EPS8 epidermal growth factor receptor pathway substrate 8 2.08061
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 2.08058
LTB4R leukotriene B4 receptor 2.07908
KRI1 KRI1 homolog (S. cerevisiae) 2.079
DES desmin 2.07703
CRTC3 CREB regulated transcription coactivator 3 2.07442
PPP6R1 protein phosphatase 6, regulatory subunit 1 2.07225
OGA O-GlcNAcase 2.07198
SAYSD1 SAYSVFN motif domain containing 1 2.07106
ORAI3 ORAI calcium release-activated calcium modulator 3 2.07069
TPM2 tropomyosin 2 (beta) 2.07015
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 2.06921
FAM110D family with sequence similarity 110, member D 2.06863
TRPC6 transient receptor potential cation channel, subfamily C, member 6 2.06847
GOLGB1 golgin B1 2.06752
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) 2.06729
SF3B4 splicing factor 3b, subunit 4, 49kDa 2.06677
POM121C POM121 transmembrane nucleoporin C 2.06572
PTBP2 polypyrimidine tract binding protein 2 2.06543
KIF21B kinesin family member 21B 2.06392
TNIP2 TNFAIP3 interacting protein 2 2.06349
IRAK1 interleukin-1 receptor-associated kinase 1 2.06299
CASP2 caspase 2, apoptosis-related cysteine peptidase 2.06236
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 2.05991
POM121 POM121 transmembrane nucleoporin 2.0599
MAP3K14 mitogen-activated protein kinase kinase kinase 14 2.05796
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae) 2.05626
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 2.05527
IL3RA interleukin 3 receptor, alpha (low affinity) 2.05457
ZNF235 zinc finger protein 235 2.05357
AKAP8L A kinase (PRKA) anchor protein 8-like 2.05225
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) 2.05134
TMC7 transmembrane channel-like 7 2.05094
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 2.05074
HELZ helicase with zinc finger 2.05056
MAST2 microtubule associated serine/threonine kinase 2 2.0505
REG1A regenerating islet-derived 1 alpha 2.04989
TRIM62 tripartite motif containing 62 2.04959
ZBTB17 zinc finger and BTB domain containing 17 2.04957
NAPSA napsin A aspartic peptidase 2.04872
ZDHHC17 zinc finger, DHHC-type containing 17 2.0484
FAM13B family with sequence similarity 13, member B 2.04773
STYK1 serine/threonine/tyrosine kinase 1 2.04664
FDXR ferredoxin reductase 2.04642
SOD3 superoxide dismutase 3, extracellular 2.04482
IRF8 interferon regulatory factor 8 2.04478
BAG3 BCL2-associated athanogene 3 2.04383
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like 2.04376
IST1 increased sodium tolerance 1 homolog (yeast) 2.04224
WFS1 Wolfram syndrome 1 (wolframin) 2.04188
ARID3B AT rich interactive domain 3B (BRIGHT-like) 2.04126
POMT2 protein-O-mannosyltransferase 2 2.04123
PTPRS protein tyrosine phosphatase, receptor type, S 2.04011
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit 2.03877
ESS2 ess-2 splicing factor homolog 2.03876
C6ORF89 chromosome 6 open reading frame 89 2.03749
TSPOAP1 TSPO associated protein 1 2.03555
PGF placental growth factor 2.03408
ETFB electron-transfer-flavoprotein, beta polypeptide 2.03189
TASL TLR adaptor interacting with endolysosomal SLC15A4 2.02858
MYH11 myosin, heavy chain 11, smooth muscle 2.02854
WDR73 WD repeat domain 73 2.02683
LUC7L3 LUC7-like 3 (S. cerevisiae) 2.02675
SLFN12 schlafen family member 12 2.02568
EPAS1 endothelial PAS domain protein 1 2.0247
KCNK3 potassium channel, two pore domain subfamily K, member 3 2.02462
RTN1 reticulon 1 2.02368
ACOT9 acyl-CoA thioesterase 9 2.02218
BBS4 Bardet-Biedl syndrome 4 2.02133
PLEKHO1 pleckstrin homology domain containing, family O member 1 2.02131
ZNF473 zinc finger protein 473 2.02037
SREK1 splicing regulatory glutamine/lysine-rich protein 1 2.02025
STAT4 signal transducer and activator of transcription 4 2.01979
RBM15B RNA binding motif protein 15B 2.01902
EFNB1 ephrin-B1 2.01763
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 2.01586
SMTN smoothelin 2.01437
SEC14L2 SEC14-like 2 (S. cerevisiae) 2.01434
DNM2 dynamin 2 2.01305
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1 2.01275
E4F1 E4F transcription factor 1 2.01206
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 2.01087
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 2.01065
RGL2 ral guanine nucleotide dissociation stimulator-like 2 2.00962
GTPBP2 GTP binding protein 2 2.00953
DST dystonin 2.00893
MARK4 MAP/microtubule affinity-regulating kinase 4 2.00882
RUNDC3A RUN domain containing 3A 2.00533
STBD1 starch binding domain 1 2.0042
ZFR2 zinc finger RNA binding protein 2 2.00414
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase 2.004
KPTN kaptin (actin binding protein) 2.00347
TPBG trophoblast glycoprotein 2.00279
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 2.0002

decreased expression

Symbol Name Standardized Value
PROS1 protein S (alpha) -8.34463
FGFR4 fibroblast growth factor receptor 4 -8.13676
PCCB propionyl CoA carboxylase, beta polypeptide -8.0185
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -7.85861
RPIA ribose 5-phosphate isomerase A -7.68951
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -7.39848
ITFG1 integrin alpha FG-GAP repeat containing 1 -7.27167
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -7.22439
PYCR1 pyrroline-5-carboxylate reductase 1 -7.2134
ENOPH1 enolase-phosphatase 1 -7.17935
MNAT1 MNAT CDK-activating kinase assembly factor 1 -6.98023
HMGA2 high mobility group AT-hook 2 -6.90054
SLC35F2 solute carrier family 35, member F2 -6.77763
PECR peroxisomal trans-2-enoyl-CoA reductase -6.67371
PGM1 phosphoglucomutase 1 -6.42611
LBR lamin B receptor -6.3689
HEATR1 HEAT repeat containing 1 -6.31203
PSRC1 proline/serine-rich coiled-coil 1 -6.30319
CDC20 cell division cycle 20 -6.24839
C2CD5 C2 calcium-dependent domain containing 5 -5.92561
RSU1 Ras suppressor protein 1 -5.84536
NIPSNAP1 nipsnap homolog 1 (C. elegans) -5.8414
CCNA2 cyclin A2 -5.8346
DNM1L dynamin 1-like -5.72983
PLS1 plastin 1 -5.69318
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -5.67393
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -5.57415
UBE3C ubiquitin protein ligase E3C -5.53445
BLMH bleomycin hydrolase -5.52883
ADI1 acireductone dioxygenase 1 -5.4038
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -5.40197
PLK1 polo-like kinase 1 -5.35168
USP6NL USP6 N-terminal like -5.17596
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -5.17403
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -5.15832
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -5.08486
MYC v-myc avian myelocytomatosis viral oncogene homolog -5.083
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -5.00338
NUP93 nucleoporin 93kDa -4.9768
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -4.86832
MRPS16 mitochondrial ribosomal protein S16 -4.75806
ISOC1 isochorismatase domain containing 1 -4.7558
UBE2C ubiquitin-conjugating enzyme E2C -4.6885
PARP1 poly (ADP-ribose) polymerase 1 -4.68096
THAP11 THAP domain containing 11 -4.63554
C5 complement component 5 -4.63059
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -4.51849
CASP7 caspase 7, apoptosis-related cysteine peptidase -4.49579
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -4.4835
AURKB aurora kinase B -4.36525
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -4.35508
STMN1 stathmin 1 -4.32567
B4GAT1 beta-1,4-glucuronyltransferase 1 -4.28834
UGDH UDP-glucose 6-dehydrogenase -4.17599
MIS18A MIS18 kinetochore protein A -4.12365
ANO10 anoctamin 10 -4.10117
SOAT2 sterol O-acyltransferase 2 -4.08691
ITGB1BP1 integrin beta 1 binding protein 1 -4.06606
CDK4 cyclin-dependent kinase 4 -4.05551
CHEK2 checkpoint kinase 2 -4.03637
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -4.02404
CETN3 centrin, EF-hand protein, 3 -3.98581
ANXA7 annexin A7 -3.96772
TMEM97 transmembrane protein 97 -3.95912
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -3.94952
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -3.9391
LYRM4 LYR motif containing 4 -3.9208
MRPL12 mitochondrial ribosomal protein L12 -3.88643
AMBP alpha-1-microglobulin/bikunin precursor -3.86582
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.86243
SAA4 serum amyloid A4, constitutive -3.83859
ALDOC aldolase C, fructose-bisphosphate -3.79549
SCARB1 scavenger receptor class B, member 1 -3.79006
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -3.76061
BIRC5 baculoviral IAP repeat containing 5 -3.75054
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 -3.72308
TCTN1 tectonic family member 1 -3.69796
CHMP6 charged multivesicular body protein 6 -3.67841
LOC124907782 dual specificity protein phosphatase 22 -3.67122
LDHD lactate dehydrogenase D -3.66025
HSPE1 heat shock 10kDa protein 1 -3.65021
NHP2 NHP2 ribonucleoprotein -3.62527
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) -3.56316
PXMP2 peroxisomal membrane protein 2, 22kDa -3.54952
TOP2B topoisomerase (DNA) II beta 180kDa -3.52421
PHKB phosphorylase kinase, beta -3.50919
ICAM3 intercellular adhesion molecule 3 -3.45379
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 -3.44236
GCSH glycine cleavage system protein H (aminomethyl carrier) -3.43585
ANAPC1 anaphase promoting complex subunit 1 -3.43184
TRIB3 tribbles pseudokinase 3 -3.41275
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) -3.39008
ZMIZ1 zinc finger, MIZ-type containing 1 -3.3875
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -3.37845
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -3.34261
DENND2D DENN/MADD domain containing 2D -3.33383
DCK deoxycytidine kinase -3.29359
ANKRD28 ankyrin repeat domain 28 -3.28917
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -3.25737
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -3.19713
LAGE3 L antigen family, member 3 -3.18576
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -3.18071
CDKN3 cyclin-dependent kinase inhibitor 3 -3.18008
LYRM1 LYR motif containing 1 -3.17788
FKBP3 FK506 binding protein 3, 25kDa -3.1758
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -3.17312
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum) -3.16946
FGL1 fibrinogen-like 1 -3.15115
APOH apolipoprotein H (beta-2-glycoprotein I) -3.14686
FGA fibrinogen alpha chain -3.11349
STAP2 signal transducing adaptor family member 2 -3.09774
QPRT quinolinate phosphoribosyltransferase -3.07416
MRPS17 mitochondrial ribosomal protein S17 -3.07185
PEG10 paternally expressed 10 -3.06954
PDIA6 protein disulfide isomerase family A, member 6 -3.0511
E2F5 E2F transcription factor 5, p130-binding -3.04331
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -3.04243
MRPS2 mitochondrial ribosomal protein S2 -3.02185
TNIP1 TNFAIP3 interacting protein 1 -3.01281
MACROD1 MACRO domain containing 1 -3.00538
WASHC4 WASH complex subunit 4 -2.98733
HADH hydroxyacyl-CoA dehydrogenase -2.98574
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog -2.97304
NT5DC2 5'-nucleotidase domain containing 2 -2.97018
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 -2.96633
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -2.96295
F9 coagulation factor IX -2.95667
VRK1 vaccinia related kinase 1 -2.95257
AHSG alpha-2-HS-glycoprotein -2.94333
AGMAT agmatine ureohydrolase (agmatinase) -2.94013
SCD stearoyl-CoA desaturase (delta-9-desaturase) -2.93184
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) -2.92805
AMDHD2 amidohydrolase domain containing 2 -2.92419
IGFBP1 insulin-like growth factor binding protein 1 -2.91691
HDAC2 histone deacetylase 2 -2.91566
PPP4C protein phosphatase 4, catalytic subunit -2.91406
ATP7B ATPase, Cu++ transporting, beta polypeptide -2.91127
TTC27 tetratricopeptide repeat domain 27 -2.90313
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -2.88569
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 -2.87436
VCAM1 vascular cell adhesion molecule 1 -2.87312
ANXA6 annexin A6 -2.86747
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.8647
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -2.85712
SKIC8 SKI8 subunit of superkiller complex -2.83745
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -2.8326
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 -2.82348
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -2.81899
HSPD1 heat shock 60kDa protein 1 (chaperonin) -2.81854
PGAM4 phosphoglycerate mutase family member 4 -2.80824
CLTC clathrin, heavy chain (Hc) -2.80502
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H -2.79725
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -2.7925
COPZ1 coatomer protein complex, subunit zeta 1 -2.79104
NUCB2 nucleobindin 2 -2.7888
CENPA centromere protein A -2.77635
PFAS phosphoribosylformylglycinamidine synthase -2.77248
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa -2.7686
EXTL2 exostosin-like glycosyltransferase 2 -2.7521
TRAPPC3 trafficking protein particle complex 3 -2.74798
CRYZ crystallin, zeta (quinone reductase) -2.74182
MYL9 myosin, light chain 9, regulatory -2.74012
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.73116
CLIC4 chloride intracellular channel 4 -2.73019
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -2.72002
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) -2.71561
CPVL carboxypeptidase, vitellogenic-like -2.71161
ANAPC15 anaphase promoting complex subunit 15 -2.71042
MSMO1 methylsterol monooxygenase 1 -2.70777
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -2.70058
WDR82 WD repeat domain 82 -2.69931
FZD4 frizzled class receptor 4 -2.69884
SEC61G Sec61 gamma subunit -2.69075
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -2.68513
APOC3 apolipoprotein C-III -2.68512
LARS2 leucyl-tRNA synthetase 2, mitochondrial -2.66972
PUM3 pumilio RNA binding family member 3 -2.66862
TOMM70 translocase of outer mitochondrial membrane 70 -2.66757
PTGES3 prostaglandin E synthase 3 (cytosolic) -2.66423
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) -2.65971
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -2.65807
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) -2.65295
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -2.65257
MPC1 mitochondrial pyruvate carrier 1 -2.65157
AURKA aurora kinase A -2.64036
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.639
MYO10 myosin X -2.63387
R3HDM2 R3H domain containing 2 -2.63128
NDUFAF3 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 -2.62177
HPS4 Hermansky-Pudlak syndrome 4 -2.59801
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -2.59307
EPS15 epidermal growth factor receptor pathway substrate 15 -2.58996
CCNB1 cyclin B1 -2.57888
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -2.57599
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.57562
CHL1 cell adhesion molecule L1-like -2.56512
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 -2.56468
SNRPF small nuclear ribonucleoprotein polypeptide F -2.56388
HAT1 histone acetyltransferase 1 -2.56181
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) -2.56
AKR1D1 aldo-keto reductase family 1, member D1 -2.55997
WDR12 WD repeat domain 12 -2.55646
RTN3 reticulon 3 -2.55461
VDAC1 voltage-dependent anion channel 1 -2.54731
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -2.54232
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme -2.54084
NCAPD2 non-SMC condensin I complex, subunit D2 -2.53207
NNT nicotinamide nucleotide transhydrogenase -2.52491
DCXR dicarbonyl/L-xylulose reductase -2.52436
APOA2 apolipoprotein A-II -2.52284
MRPL42 mitochondrial ribosomal protein L42 -2.522
GPHN gephyrin -2.51989
IDI1 isopentenyl-diphosphate delta isomerase 1 -2.51236
HEBP1 heme binding protein 1 -2.50508
DHCR24 24-dehydrocholesterol reductase -2.50479
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -2.50168
LOC112694756 uncharaterized LOC112694756 -2.50135
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.50125
ALG6 ALG6, alpha-1,3-glucosyltransferase -2.4954
MRPL35 mitochondrial ribosomal protein L35 -2.48972
MRPS35 mitochondrial ribosomal protein S35 -2.48834
MPHOSPH6 M-phase phosphoprotein 6 -2.48682
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -2.48638
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -2.48325
MSH2 mutS homolog 2 -2.4746
WDR18 WD repeat domain 18 -2.47429
HPD 4-hydroxyphenylpyruvate dioxygenase -2.46474
NUP37 nucleoporin 37kDa -2.46232
TFB1M transcription factor B1, mitochondrial -2.46025
NDC1 NDC1 transmembrane nucleoporin -2.45631
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -2.45018
RPL36AL ribosomal protein L36a-like -2.44187
GAR1 GAR1 ribonucleoprotein -2.44106
RFC2 replication factor C (activator 1) 2, 40kDa -2.44077
MRPL19 mitochondrial ribosomal protein L19 -2.43646
GLB1 galactosidase, beta 1 -2.43386
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 -2.43082
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -2.42872
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa -2.4266
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) -2.4219
FAM3C family with sequence similarity 3, member C -2.42163
PBK PDZ binding kinase -2.42128
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -2.41764
GPX4 glutathione peroxidase 4 -2.41617
CNIH1 cornichon family AMPA receptor auxiliary protein 1 -2.4129
TOP2A topoisomerase (DNA) II alpha 170kDa -2.41279
SDAD1 SDA1 domain containing 1 -2.40889
PDIA5 protein disulfide isomerase family A, member 5 -2.40813
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -2.40769
INHBE inhibin, beta E -2.40697
ATP5MC3 ATP synthase membrane subunit c locus 3 -2.39984
TM9SF3 transmembrane 9 superfamily member 3 -2.39754
UQCRC2 ubiquinol-cytochrome c reductase core protein II -2.39053
C8A complement component 8, alpha polypeptide -2.38476
LRRC20 leucine rich repeat containing 20 -2.37996
NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) -2.37795
MBL2 mannose-binding lectin (protein C) 2, soluble -2.37091
FGB fibrinogen beta chain -2.37033
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 -2.36463
NFIL3 nuclear factor, interleukin 3 regulated -2.3559
ERBB3 erb-b2 receptor tyrosine kinase 3 -2.35254
SLIRP SRA stem-loop interacting RNA binding protein -2.35192
TRAP1 TNF receptor-associated protein 1 -2.35171
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -2.35119
ATP5MC1 ATP synthase membrane subunit c locus 1 -2.3504
PCNA proliferating cell nuclear antigen -2.34667
ELAVL1 ELAV like RNA binding protein 1 -2.34471
SINHCAF SIN3-HDAC complex associated factor -2.34352
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -2.34271
CARMIL1 capping protein regulator and myosin 1 linker 1 -2.34033
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 -2.33425
NID2 nidogen 2 (osteonidogen) -2.32521
GLRX5 glutaredoxin 5 -2.32395
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.32196
GTF2H5 general transcription factor IIH, polypeptide 5 -2.32117
ORM2 orosomucoid 2 -2.31948
ARHGAP19 Rho GTPase activating protein 19 -2.31796
PLG plasminogen -2.31759
UROS uroporphyrinogen III synthase -2.31069
PDIA4 protein disulfide isomerase family A, member 4 -2.30455
GTF2A2 general transcription factor IIA, 2, 12kDa -2.30438
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 -2.30363
ANG angiogenin, ribonuclease, RNase A family, 5 -2.30356
KIF15 kinesin family member 15 -2.3024
PARN poly(A)-specific ribonuclease -2.2959
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.29011
PPIH peptidylprolyl isomerase H (cyclophilin H) -2.28964
SIPA1L3 signal-induced proliferation-associated 1 like 3 -2.28946
CNOT7 CCR4-NOT transcription complex, subunit 7 -2.28215
MTCH2 mitochondrial carrier 2 -2.27387
GNAS GNAS complex locus -2.26592
SATB1 SATB homeobox 1 -2.26569
COMMD1 copper metabolism (Murr1) domain containing 1 -2.26098
CRIPTO3 cripto, EGF-CFC family member 3 -2.2599
CPB2 carboxypeptidase B2 (plasma) -2.25921
ZNF83 zinc finger protein 83 -2.25868
SPDEF SAM pointed domain containing ETS transcription factor -2.25761
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -2.25619
BCCIP BRCA2 and CDKN1A interacting protein -2.24737
AP1AR adaptor-related protein complex 1 associated regulatory protein -2.24251
PANK3 pantothenate kinase 3 -2.24202
LGALS8 lectin, galactoside-binding, soluble, 8 -2.23238
S100A4 S100 calcium binding protein A4 -2.23233
BET1 Bet1 golgi vesicular membrane trafficking protein -2.23229
IFT52 intraflagellar transport 52 -2.22881
RUVBL1 RuvB-like AAA ATPase 1 -2.22622
PKP2 plakophilin 2 -2.22591
GLOD4 glyoxalase domain containing 4 -2.22403
SARS2 seryl-tRNA synthetase 2, mitochondrial -2.22369
WDR45B WD repeat domain 45B -2.22361
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 -2.22289
ENY2 enhancer of yellow 2 homolog (Drosophila) -2.22255
ITGB5 integrin, beta 5 -2.21964
FASTKD3 FAST kinase domains 3 -2.21963
DHRS2 dehydrogenase/reductase (SDR family) member 2 -2.21934
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -2.21904
SEC13 SEC13 homolog (S. cerevisiae) -2.21661
KIF4A kinesin family member 4A -2.21635
GLDC glycine dehydrogenase (decarboxylating) -2.21578
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 -2.21517
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.2142
HIBCH 3-hydroxyisobutyryl-CoA hydrolase -2.20718
NME1 NME/NM23 nucleoside diphosphate kinase 1 -2.20406
RHOBTB1 Rho-related BTB domain containing 1 -2.20224
TTC3 tetratricopeptide repeat domain 3 -2.2002
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 -2.19785
RNF144A ring finger protein 144A -2.1934
CANX calnexin -2.19136
APRT adenine phosphoribosyltransferase -2.19126
PEPD peptidase D -2.18367
GCA grancalcin, EF-hand calcium binding protein -2.17787
GET1 guided entry of tail-anchored proteins factor 1 -2.17697
NPM3 nucleophosmin/nucleoplasmin 3 -2.17378
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 -2.17201
MANF mesencephalic astrocyte-derived neurotrophic factor -2.17186
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.17111
TSPAN4 tetraspanin 4 -2.17075
NAV3 neuron navigator 3 -2.16833
CDK1 cyclin-dependent kinase 1 -2.16176
RPS5 ribosomal protein S5 -2.15943
DHCR7 7-dehydrocholesterol reductase -2.15746
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 -2.15551
PUS1 pseudouridylate synthase 1 -2.155
GMPPA GDP-mannose pyrophosphorylase A -2.15352
TBC1D16 TBC1 domain family, member 16 -2.14893
RPL36 ribosomal protein L36 -2.14879
MRS2 MRS2 magnesium transporter -2.14742
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4 -2.14451
COL6A3 collagen, type VI, alpha 3 -2.14121
EXOSC8 exosome component 8 -2.1386
UXT ubiquitously-expressed, prefoldin-like chaperone -2.13592
STX8 syntaxin 8 -2.13393
A1CF APOBEC1 complementation factor -2.13073
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) -2.12853
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 -2.12417
EBNA1BP2 EBNA1 binding protein 2 -2.12287
CNN3 calponin 3, acidic -2.12227
THY1 Thy-1 cell surface antigen -2.12118
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) -2.12007
BABAM1 BRISC and BRCA1 A complex member 1 -2.11898
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.11828
LAS1L LAS1-like (S. cerevisiae) -2.11609
LRPPRC leucine-rich pentatricopeptide repeat containing -2.10565
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta -2.10395
HSPA12A heat shock 70kDa protein 12A -2.10084
SORD sorbitol dehydrogenase -2.10062
SERP1 stress-associated endoplasmic reticulum protein 1 -2.1004
CEP83 centrosomal protein 83kDa -2.10034
ATP5PD ATP synthase peripheral stalk subunit d -2.09922
GAS2 growth arrest-specific 2 -2.09908
MSH6 mutS homolog 6 -2.09891
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -2.0963
CBFB core-binding factor, beta subunit -2.09448
KYAT3 kynurenine aminotransferase 3 -2.09149
SEC61B Sec61 beta subunit -2.09117
CALU calumenin -2.08966
ERBB2 erb-b2 receptor tyrosine kinase 2 -2.0874
FXN frataxin -2.0873
ICAM2 intercellular adhesion molecule 2 -2.08533
HMGB2 high mobility group box 2 -2.08185
FTO fat mass and obesity associated -2.07972
FBXO5 F-box protein 5 -2.07874
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa -2.07541
ZNHIT1 zinc finger, HIT-type containing 1 -2.07392
FBF1 Fas (TNFRSF6) binding factor 1 -2.07028
KNG1 kininogen 1 -2.06834
TRIP13 thyroid hormone receptor interactor 13 -2.06808
MCM10 minichromosome maintenance complex component 10 -2.05692
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog -2.05454
ARL2 ADP-ribosylation factor-like 2 -2.05254
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 -2.05196
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) -2.05153
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) -2.04754
FGG fibrinogen gamma chain -2.04587
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 -2.0446
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites -2.04234
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) -2.04186
ENTR1 endosome associated trafficking regulator 1 -2.03793
PARP2 poly (ADP-ribose) polymerase 2 -2.03702
USP1 ubiquitin specific peptidase 1 -2.03507
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) -2.03237
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) -2.03163
TPD52-MRPS28 TPD52-MRPS28 readthrough -2.02999
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 -2.02933
FBL fibrillarin -2.02884
ATP5PO ATP synthase peripheral stalk subunit OSCP -2.02802
ADRA2A adrenoceptor alpha 2A -2.02792
WASF3 WAS protein family, member 3 -2.02409
EIF2D eukaryotic translation initiation factor 2D -2.02267
DMAC2L distal membrane arm assembly component 2 like -2.02114
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa -2.01955
APOM apolipoprotein M -2.01712
FUS FUS RNA binding protein -2.015
MAGOHB mago-nashi homolog B (Drosophila) -2.01435
VRK2 vaccinia related kinase 2 -2.01272
MCTS1 malignant T cell amplified sequence 1 -2.0028
TMEM258 transmembrane protein 258 -2.00256
BPIFA1 BPI fold containing family A, member 1 -2.00157