CRCGN013_HEPG2_24H:K04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description o-phenylenediamine.2hcl 5.1 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

978 genes differentially expressed following the CRCGN013_HEPG2_24H:K04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABHD4 abhydrolase domain containing 4 10.0
INPP1 inositol polyphosphate-1-phosphatase 9.31371
BLCAP bladder cancer associated protein 9.23311
CNPY3 canopy FGF signaling regulator 3 9.12064
LRP10 low density lipoprotein receptor-related protein 10 9.04543
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 8.53361
DDB2 damage-specific DNA binding protein 2, 48kDa 8.45955
CCDC92 coiled-coil domain containing 92 7.90563
CTSL cathepsin L 7.68285
MICALL1 MICAL-like 1 7.65232
TUBB6 tubulin, beta 6 class V 7.37747
DUSP14 dual specificity phosphatase 14 7.31804
TIMP2 TIMP metallopeptidase inhibitor 2 6.86697
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 6.71034
NR1H2 nuclear receptor subfamily 1, group H, member 2 6.61842
CDPF1 cysteine-rich, DPF motif domain containing 1 6.50353
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 6.41148
GPC1 glypican 1 6.2974
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 6.11326
KLHL21 kelch-like family member 21 6.06777
ANKRD10 ankyrin repeat domain 10 5.87825
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 5.8065
KHDC4 KH domain containing 4, pre-mRNA splicing factor 5.74519
IL4R interleukin 4 receptor 5.67417
GADD45A growth arrest and DNA-damage-inducible, alpha 5.41445
LSR lipolysis stimulated lipoprotein receptor 5.39632
IGFBP3 insulin-like growth factor binding protein 3 5.31455
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 5.2777
RALGDS ral guanine nucleotide dissociation stimulator 5.10813
KDM5A lysine (K)-specific demethylase 5A 5.02181
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 4.97207
TOR1A torsin family 1, member A (torsin A) 4.96692
KIFBP kinesin family binding protein 4.85428
CASC3 cancer susceptibility candidate 3 4.79638
STX1A syntaxin 1A (brain) 4.77559
CEMIP2 cell migration inducing hyaluronidase 2 4.75116
MCOLN1 mucolipin 1 4.72163
NPDC1 neural proliferation, differentiation and control, 1 4.71584
KEAP1 kelch-like ECH-associated protein 1 4.70162
PRKCQ protein kinase C, theta 4.60355
FOXJ3 forkhead box J3 4.59427
SKIC2 SKI2 subunit of superkiller complex 4.58522
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 4.54181
EML3 echinoderm microtubule associated protein like 3 4.43965
ULK1 unc-51 like autophagy activating kinase 1 4.42867
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 4.36009
ZW10 zw10 kinetochore protein 4.24465
TERF2IP telomeric repeat binding factor 2, interacting protein 4.20866
ADGRG1 adhesion G protein-coupled receptor G1 4.17261
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 4.16038
FOSL1 FOS-like antigen 1 4.13793
MINDY1 MINDY lysine 48 deubiquitinase 1 4.13158
CGRRF1 cell growth regulator with ring finger domain 1 4.03786
PLK3 polo-like kinase 3 4.00742
ASCC3 activating signal cointegrator 1 complex subunit 3 3.9782
TXNRD1 thioredoxin reductase 1 3.97615
PRAF2 PRA1 domain family, member 2 3.91432
DHRS7 dehydrogenase/reductase (SDR family) member 7 3.89276
ELAC2 elaC ribonuclease Z 2 3.75087
RNF25 ring finger protein 25 3.7197
KDM3A lysine (K)-specific demethylase 3A 3.69659
CSRNP2 cysteine-serine-rich nuclear protein 2 3.6965
PHLDA3 pleckstrin homology-like domain, family A, member 3 3.64489
SMAD3 SMAD family member 3 3.63669
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 3.63665
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 3.62911
CLK3 CDC-like kinase 3 3.61223
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 3.61044
SOCS2 suppressor of cytokine signaling 2 3.60801
FOS FBJ murine osteosarcoma viral oncogene homolog 3.58358
CDC45 cell division cycle 45 3.55385
MAD2L1BP MAD2L1 binding protein 3.54471
ALAS1 5'-aminolevulinate synthase 1 3.53925
SPATA20 spermatogenesis associated 20 3.52179
MBD1 methyl-CpG binding domain protein 1 3.51725
PNKP polynucleotide kinase 3'-phosphatase 3.47238
TOMM34 translocase of outer mitochondrial membrane 34 3.44422
TMEM115 transmembrane protein 115 3.4272
FOXO4 forkhead box O4 3.41429
SCPEP1 serine carboxypeptidase 1 3.40969
YIPF3 Yip1 domain family, member 3 3.40109
NOTCH1 notch 1 3.39579
BAD BCL2-associated agonist of cell death 3.39341
MVP major vault protein 3.39302
ATG2A autophagy related 2A 3.3688
COG7 component of oligomeric golgi complex 7 3.35905
NISCH nischarin 3.34623
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 3.34608
DUSP6 dual specificity phosphatase 6 3.33802
HCFC2 host cell factor C2 3.32689
PRKCD protein kinase C, delta 3.32459
SQOR sulfide quinone oxidoreductase 3.3131
IGHMBP2 immunoglobulin mu binding protein 2 3.30344
ARID5A AT rich interactive domain 5A (MRF1-like) 3.29951
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 3.29919
DGKA diacylglycerol kinase, alpha 80kDa 3.27063
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 3.26505
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) 3.25646
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.22587
SETD1A SET domain containing 1A 3.22031
MSMB microseminoprotein, beta- 3.21842
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15 3.19677
ATG9A autophagy related 9A 3.16527
CCND3 cyclin D3 3.14631
CYTH2 cytohesin 2 3.14265
FAM110D family with sequence similarity 110, member D 3.13814
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa 3.13198
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 3.1274
CIC capicua transcriptional repressor 3.11917
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2 3.11149
PI4KB phosphatidylinositol 4-kinase, catalytic, beta 3.11127
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 3.10879
TESK1 testis-specific kinase 1 3.10553
RCOR3 REST corepressor 3 3.09528
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 3.09221
PILRB paired immunoglobin-like type 2 receptor beta 3.0864
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28 3.08526
AVPI1 arginine vasopressin-induced 1 3.07068
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 3.06976
IER3 immediate early response 3 3.06787
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 3.0678
BARX1 BARX homeobox 1 3.05293
ZBTB48 zinc finger and BTB domain containing 48 3.05187
MAP7D1 MAP7 domain containing 1 3.04268
POMT1 protein-O-mannosyltransferase 1 3.04146
TP53I3 tumor protein p53 inducible protein 3 3.01724
PORCN porcupine homolog (Drosophila) 3.01551
AKAP8L A kinase (PRKA) anchor protein 8-like 3.01031
FUZ fuzzy planar cell polarity protein 2.99813
CALCOCO1 calcium binding and coiled-coil domain 1 2.99588
LMBR1L limb development membrane protein 1-like 2.97994
GPATCH3 G patch domain containing 3 2.97433
PHF1 PHD finger protein 1 2.97231
GABARAPL1 GABA(A) receptor-associated protein like 1 2.96932
CDIP1 cell death-inducing p53 target 1 2.96538
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) 2.96421
XPC xeroderma pigmentosum, complementation group C 2.96245
RTL10 retrotransposon Gag like 10 2.95818
WDR73 WD repeat domain 73 2.95501
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 2.94922
SIRT7 sirtuin 7 2.94442
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 2.94303
FASTKD5 FAST kinase domains 5 2.94182
DUSP3 dual specificity phosphatase 3 2.93789
RIN1 Ras and Rab interactor 1 2.93526
CEL carboxyl ester lipase 2.93306
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 2.93137
TKTL1 transketolase-like 1 2.92271
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 2.91421
GPN2 GPN-loop GTPase 2 2.91339
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 2.91241
FNBP4 formin binding protein 4 2.91134
TOE1 target of EGR1, member 1 (nuclear) 2.89421
SCAND1 SCAN domain containing 1 2.86715
AEN apoptosis enhancing nuclease 2.86304
CNPPD1 cyclin Pas1/PHO80 domain containing 1 2.85175
ASB6 ankyrin repeat and SOCS box containing 6 2.84362
RAP1GAP RAP1 GTPase activating protein 2.83615
HSPA1A heat shock 70kDa protein 1A 2.83093
ELMO3 engulfment and cell motility 3 2.81549
ASB7 ankyrin repeat and SOCS box containing 7 2.80346
KAT6B K(lysine) acetyltransferase 6B 2.79887
CCNT1 cyclin T1 2.79573
ARID4B AT rich interactive domain 4B (RBP1-like) 2.78364
TRIM62 tripartite motif containing 62 2.77826
TRIM8 tripartite motif containing 8 2.77273
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 2.76788
CSAD cysteine sulfinic acid decarboxylase 2.76722
GATA2 GATA binding protein 2 2.76198
LRRC41 leucine rich repeat containing 41 2.76116
PHKG2 phosphorylase kinase, gamma 2 (testis) 2.75865
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.75532
THSD1 thrombospondin, type I, domain containing 1 2.74593
ZNF212 zinc finger protein 212 2.74494
ZNF219 zinc finger protein 219 2.73877
ARAF A-Raf proto-oncogene, serine/threonine kinase 2.73182
JAG2 jagged 2 2.73049
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 2.72758
TIGAR TP53 induced glycolysis regulatory phosphatase 2.72493
HAND2 heart and neural crest derivatives expressed 2 2.72259
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 2.71637
NAPSA napsin A aspartic peptidase 2.71453
TCF15 transcription factor 15 (basic helix-loop-helix) 2.71405
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 2.71297
MXD4 MAX dimerization protein 4 2.71153
NIT1 nitrilase 1 2.70973
PHC1 polyhomeotic homolog 1 (Drosophila) 2.70006
ZNF692 zinc finger protein 692 2.6914
TJAP1 tight junction associated protein 1 (peripheral) 2.68214
TRIM11 tripartite motif containing 11 2.67827
PIGG phosphatidylinositol glycan anchor biosynthesis, class G 2.67764
ZDHHC18 zinc finger, DHHC-type containing 18 2.67071
SZT2 seizure threshold 2 homolog (mouse) 2.66803
PI4K2A phosphatidylinositol 4-kinase type 2 alpha 2.66454
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa 2.6597
NFE2L1 nuclear factor, erythroid 2-like 1 2.65681
AAR2 AAR2 splicing factor homolog (S. cerevisiae) 2.65456
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 2.65091
NOP2 NOP2 nucleolar protein 2.65047
SLC35F6 solute carrier family 35, member F6 2.6484
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 2.63369
MUL1 mitochondrial E3 ubiquitin protein ligase 1 2.62703
RB1CC1 RB1-inducible coiled-coil 1 2.62648
PTBP2 polypyrimidine tract binding protein 2 2.62584
E4F1 E4F transcription factor 1 2.62422
GBA1 glucosylceramidase beta 1 2.62284
IRF3 interferon regulatory factor 3 2.62045
ITPKC inositol-trisphosphate 3-kinase C 2.61875
POMT2 protein-O-mannosyltransferase 2 2.61672
FURIN furin (paired basic amino acid cleaving enzyme) 2.60075
FBRS fibrosin 2.60066
CSNK1E casein kinase 1, epsilon 2.59403
AXIN1 axin 1 2.59026
FHIP2B FHF complex subunit HOOK interacting protein 2B 2.58839
ZFPM1 zinc finger protein, FOG family member 1 2.5881
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis) 2.58721
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14 2.57951
LTBP4 latent transforming growth factor beta binding protein 4 2.57924
FBXO2 F-box protein 2 2.57211
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 2.57014
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 2.56482
NPFFR1 neuropeptide FF receptor 1 2.56419
KLHL36 kelch-like family member 36 2.56185
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40 2.55684
MOK MOK protein kinase 2.5557
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 2.55562
TRIP12 thyroid hormone receptor interactor 12 2.55151
LOC124904942 uncharacterized LOC124904942 2.54981
CCNL2 cyclin L2 2.54407
SPEG SPEG complex locus 2.54326
CBX6 chromobox homolog 6 2.54176
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein 2.54147
EVX1 even-skipped homeobox 1 2.5341
STX4 syntaxin 4 2.52631
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 2.52572
HPS6 Hermansky-Pudlak syndrome 6 2.52543
PEX11A peroxisomal biogenesis factor 11 alpha 2.52428
UBAP1 ubiquitin associated protein 1 2.52189
GOLGA8A golgin A8 family, member A 2.51781
NUCB1 nucleobindin 1 2.5146
TIMP1 TIMP metallopeptidase inhibitor 1 2.51027
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 2.50958
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like 2.50662
ADAMTSL2 ADAMTS-like 2 2.50589
C6ORF89 chromosome 6 open reading frame 89 2.50344
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 2.49472
ANAPC2 anaphase promoting complex subunit 2 2.48586
GALE UDP-galactose-4-epimerase 2.48442
TMEM59 transmembrane protein 59 2.48278
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 2.48158
GSDME gasdermin E 2.48039
ZNF79 zinc finger protein 79 2.47432
LIF leukemia inhibitory factor 2.4637
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 2.45931
ZNF195 zinc finger protein 195 2.45522
CCDC86 coiled-coil domain containing 86 2.45519
PRR14 proline rich 14 2.45302
INPP5K inositol polyphosphate-5-phosphatase K 2.45103
BYSL bystin-like 2.44905
WDR6 WD repeat domain 6 2.44884
TEAD3 TEA domain family member 3 2.44314
ORAI3 ORAI calcium release-activated calcium modulator 3 2.4392
TENT2 terminal nucleotidyltransferase 2 2.43402
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 2.42461
SARM1 sterile alpha and TIR motif containing 1 2.42159
EGFL8 EGF-like-domain, multiple 8 2.42101
MAPKBP1 mitogen-activated protein kinase binding protein 1 2.41712
CCDC57 coiled-coil domain containing 57 2.41673
ZNHIT2 zinc finger, HIT-type containing 2 2.41528
ZNF282 zinc finger protein 282 2.41399
BAX BCL2-associated X protein 2.41301
ZNF324 zinc finger protein 324 2.41068
CRLF2 cytokine receptor-like factor 2 2.40488
STOM stomatin 2.4026
COL4A6 collagen, type IV, alpha 6 2.39702
RGPD1 RANBP2-like and GRIP domain containing 1 2.39587
CES1 carboxylesterase 1 2.3941
SMTN smoothelin 2.39326
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 2.39057
PPARG peroxisome proliferator-activated receptor gamma 2.39056
SERINC1 serine incorporator 1 2.3891
IDE insulin-degrading enzyme 2.38447
PRRC2A proline-rich coiled-coil 2A 2.37469
BRMS1L breast cancer metastasis-suppressor 1-like 2.37455
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 2.37192
PRPF3 pre-mRNA processing factor 3 2.37147
TRIP6 thyroid hormone receptor interactor 6 2.37141
H2BC21 H2B clustered histone 21 2.37067
TBKBP1 TBK1 binding protein 1 2.36397
KRT17 keratin 17, type I 2.36346
ZNF8 zinc finger protein 8 2.36318
TDP2 tyrosyl-DNA phosphodiesterase 2 2.35766
PRKD2 protein kinase D2 2.35718
MEF2D myocyte enhancer factor 2D 2.35583
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase 2.35501
TMUB2 transmembrane and ubiquitin-like domain containing 2 2.353
SIRT1 sirtuin 1 2.35176
ZNF318 zinc finger protein 318 2.3513
HDAC5 histone deacetylase 5 2.35028
GSTT2B glutathione S-transferase theta 2B (gene/pseudogene) 2.3502
RIC8A RIC8 guanine nucleotide exchange factor A 2.34747
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 2.34624
AGAP4 ArfGAP with GTPase domain, ankyrin repeat and PH domain 4 2.34605
BECN1 beclin 1, autophagy related 2.34586
PGF placental growth factor 2.3455
ESS2 ess-2 splicing factor homolog 2.3449
DDR1 discoidin domain receptor tyrosine kinase 1 2.34438
NSUN3 NOP2/Sun domain family, member 3 2.34221
PHF20L1 PHD finger protein 20-like 1 2.34069
CDK20 cyclin-dependent kinase 20 2.33819
IKZF4 IKAROS family zinc finger 4 (Eos) 2.33184
FASN fatty acid synthase 2.33053
CHD8 chromodomain helicase DNA binding protein 8 2.33029
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 2.32908
SFTPB surfactant protein B 2.32809
SQSTM1 sequestosome 1 2.32691
LTB4R leukotriene B4 receptor 2.323
SPAG9 sperm associated antigen 9 2.32069
USP20 ubiquitin specific peptidase 20 2.31934
RUSC2 RUN and SH3 domain containing 2 2.31704
LOXL1 lysyl oxidase-like 1 2.31697
MIDEAS mitotic deacetylase associated SANT domain protein 2.31589
GPR87 G protein-coupled receptor 87 2.31296
IP6K2 inositol hexakisphosphate kinase 2 2.31191
SYNGR3 synaptogyrin 3 2.30922
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 2.30777
FSTL3 follistatin-like 3 (secreted glycoprotein) 2.30237
MAP3K10 mitogen-activated protein kinase kinase kinase 10 2.29765
ERCC5 excision repair cross-complementation group 5 2.29752
ZNF562 zinc finger protein 562 2.29666
HOXC4 homeobox C4 2.29661
HMBOX1 homeobox containing 1 2.2932
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 2.29312
ZNF446 zinc finger protein 446 2.29185
ZNF467 zinc finger protein 467 2.28844
TSPYL2 TSPY-like 2 2.2874
RGL2 ral guanine nucleotide dissociation stimulator-like 2 2.28515
MDFI MyoD family inhibitor 2.28407
TNIP1 TNFAIP3 interacting protein 1 2.28104
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 2.28044
LHB luteinizing hormone beta polypeptide 2.27756
TRAFD1 TRAF-type zinc finger domain containing 1 2.27697
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 2.276
SLCO3A1 solute carrier organic anion transporter family, member 3A1 2.27378
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 2.27284
ROM1 retinal outer segment membrane protein 1 2.27283
ERCC3 excision repair cross-complementation group 3 2.27198
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) 2.26948
ACTL8 actin-like 8 2.26831
NBR1 neighbor of BRCA1 gene 1 2.26721
PXDC1 PX domain containing 1 2.2582
MEA1 male-enhanced antigen 1 2.25736
BSDC1 BSD domain containing 1 2.25696
HROB homologous recombination factor with OB-fold 2.2567
MAP3K14 mitogen-activated protein kinase kinase kinase 14 2.25351
HDAC7 histone deacetylase 7 2.25347
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 2.25332
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa 2.25316
IL17RA interleukin 17 receptor A 2.25297
ZFTRAF1 zinc finger TRAF-type containing 1 2.25151
OFD1 oral-facial-digital syndrome 1 2.25127
CROT carnitine O-octanoyltransferase 2.25043
CIRSR corepressor of RBPJ and splicing regulator 2.24299
KATNIP katanin interacting protein 2.24188
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 2.24003
TLE6 transducin-like enhancer of split 6 2.23904
INO80B INO80 complex subunit B 2.2389
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22 2.23655
MED9 mediator complex subunit 9 2.23638
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 2.23551
CLBA1 clathrin binding box of aftiphilin containing 1 2.23177
ZNF358 zinc finger protein 358 2.23162
MED15 mediator complex subunit 15 2.23087
EFNB1 ephrin-B1 2.23032
SYNRG synergin, gamma 2.22979
EBLN2 endogenous Bornavirus-like nucleoprotein 2 2.22683
TACC2 transforming, acidic coiled-coil containing protein 2 2.22681
RFX5 regulatory factor X, 5 (influences HLA class II expression) 2.2243
PLD3 phospholipase D family, member 3 2.22162
ZNF384 zinc finger protein 384 2.21958
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B 2.21823
PLEC plectin 2.21817
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit 2.21786
TBC1D17 TBC1 domain family, member 17 2.2149
FDXR ferredoxin reductase 2.2149
ROGDI rogdi homolog (Drosophila) 2.21421
HSF4 heat shock transcription factor 4 2.2142
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa 2.21404
MICALL2 MICAL-like 2 2.21154
RETREG2 reticulophagy regulator family member 2 2.20435
TFE3 transcription factor binding to IGHM enhancer 3 2.19925
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 2.19791
THUMPD2 THUMP domain containing 2 2.19685
MTCH1 mitochondrial carrier 1 2.19635
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.19145
HMX1 H6 family homeobox 1 2.1886
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 2.18851
SNIP1 Smad nuclear interacting protein 1 2.18588
CTF1 cardiotrophin 1 2.18562
ANXA8L1 annexin A8-like 1 2.18427
ELAVL3 ELAV like neuron-specific RNA binding protein 3 2.18074
ADO 2-aminoethanethiol (cysteamine) dioxygenase 2.17773
HAUS2 HAUS augmin-like complex, subunit 2 2.17422
BPNT2 3'(2'), 5'-bisphosphate nucleotidase 2 2.17323
RING1 ring finger protein 1 2.17271
MZF1 myeloid zinc finger 1 2.17199
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 2.17129
THBS3 thrombospondin 3 2.17061
KPTN kaptin (actin binding protein) 2.16998
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 2.16893
PROCR protein C receptor, endothelial 2.16735
CUL7 cullin 7 2.16718
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 2.16609
FAM3A family with sequence similarity 3, member A 2.16582
PPIE peptidylprolyl isomerase E (cyclophilin E) 2.16533
MACO1 macoilin 1 2.16362
POLL polymerase (DNA directed), lambda 2.15931
PLCH2 phospholipase C, eta 2 2.15805
HBEGF heparin-binding EGF-like growth factor 2.14622
ZNF783 zinc finger family member 783 2.14548
MICA MHC class I polypeptide-related sequence A 2.14498
NPIPB4 nuclear pore complex interacting protein family, member B4 2.14262
ANGPTL4 angiopoietin-like 4 2.14243
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5 2.13646
PPP2R2D protein phosphatase 2, regulatory subunit B, delta 2.13484
SCRIB scribbled planar cell polarity protein 2.13424
DCTN5 dynactin 5 (p25) 2.13344
SH2D2A SH2 domain containing 2A 2.13275
MARCHF5 membrane associated ring-CH-type finger 5 2.13075
CNPY4 canopy FGF signaling regulator 4 2.13072
ZSWIM8 zinc finger, SWIM-type containing 8 2.13008
RNF40 ring finger protein 40, E3 ubiquitin protein ligase 2.12394
KRT5 keratin 5, type II 2.12082
VAT1 vesicle amine transport 1 2.11753
MBTPS1 membrane-bound transcription factor peptidase, site 1 2.11706
TFCP2 transcription factor CP2 2.11543
SAP25 Sin3A-associated protein, 25kDa 2.11517
UNC45A unc-45 homolog A (C. elegans) 2.11267
GNL1 guanine nucleotide binding protein-like 1 2.11151
ZNF335 zinc finger protein 335 2.10918
ADGRE5 adhesion G protein-coupled receptor E5 2.10839
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae) 2.10746
KIF21B kinesin family member 21B 2.10718
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 2.10698
GSTM2 glutathione S-transferase mu 2 (muscle) 2.1066
UNC13D unc-13 homolog D (C. elegans) 2.10429
ZNF473 zinc finger protein 473 2.09947
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 2.09904
COQ6 coenzyme Q6 monooxygenase 2.09849
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.09711
KRI1 KRI1 homolog (S. cerevisiae) 2.09374
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit 2.09089
PICK1 protein interacting with PRKCA 1 2.08806
SCMH1 sex comb on midleg homolog 1 (Drosophila) 2.08712
MUTYH mutY homolog 2.08642
DOK4 docking protein 4 2.08359
TLE3 transducin-like enhancer of split 3 2.08295
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 2.08185
MARK4 MAP/microtubule affinity-regulating kinase 4 2.08014
PLA2G15 phospholipase A2, group XV 2.07908
ZNF672 zinc finger protein 672 2.07593
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 2.07456
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae) 2.07381
SUN2 Sad1 and UNC84 domain containing 2 2.06616
KLK2 kallikrein-related peptidase 2 2.06611
CREB1 cAMP responsive element binding protein 1 2.06563
IGFALS insulin-like growth factor binding protein, acid labile subunit 2.06543
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 2.06426
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae) 2.06391
LOC128125814 uncharacterized LOC128125814 2.06352
ARSA arylsulfatase A 2.06165
ELF4 E74-like factor 4 (ets domain transcription factor) 2.06162
FAM131A family with sequence similarity 131, member A 2.06151
BICRA BRD4 interacting chromatin remodeling complex associated protein 2.06134
TP53BP1 tumor protein p53 binding protein 1 2.05927
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit 2.05851
CAMTA2 calmodulin binding transcription activator 2 2.05818
TRAPPC14 trafficking protein particle complex subunit 14 2.05471
KDM4A lysine (K)-specific demethylase 4A 2.05457
ZDHHC24 zinc finger, DHHC-type containing 24 2.05368
PACSIN1 protein kinase C and casein kinase substrate in neurons 1 2.05223
COL17A1 collagen, type XVII, alpha 1 2.05054
WDR26 WD repeat domain 26 2.05046
PTK7 protein tyrosine kinase 7 (inactive) 2.05023
ZXDC ZXD family zinc finger C 2.04711
PHIP pleckstrin homology domain interacting protein 2.04585
EPS8L2 EPS8-like 2 2.04555
ISYNA1 inositol-3-phosphate synthase 1 2.04487
FBXL12 F-box and leucine-rich repeat protein 12 2.04462
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 2.04408
COL7A1 collagen, type VII, alpha 1 2.04402
INA internexin neuronal intermediate filament protein, alpha 2.04248
CRIPT cysteine-rich PDZ-binding protein 2.04077
PANK4 pantothenate kinase 4 2.0404
UBR2 ubiquitin protein ligase E3 component n-recognin 2 2.03974
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 2.03675
ITCH itchy E3 ubiquitin protein ligase 2.03645
SLC12A9 solute carrier family 12, member 9 2.03614
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 2.03593
OXCT2 3-oxoacid CoA transferase 2 2.03432
HOXA1 homeobox A1 2.03299
GRN granulin 2.03181
GAS6 growth arrest-specific 6 2.03129
SIN3B SIN3 transcription regulator family member B 2.03125
RETREG3 reticulophagy regulator family member 3 2.0292
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase 2.02919
MSL1 male-specific lethal 1 homolog (Drosophila) 2.02917
CHIC2 cysteine-rich hydrophobic domain 2 2.02788
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 2.02704
TPP2 tripeptidyl peptidase II 2.0243
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) 2.02091
SAFB2 scaffold attachment factor B2 2.01879
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 2.01842
SOCS3 suppressor of cytokine signaling 3 2.0177
ZNF222 zinc finger protein 222 2.01609
MPPE1 metallophosphoesterase 1 2.0148
MAPK7 mitogen-activated protein kinase 7 2.01433
MBOAT7 membrane bound O-acyltransferase domain containing 7 2.01293
KDM6B lysine (K)-specific demethylase 6B 2.01253
ZNF532 zinc finger protein 532 2.00951
TTC17 tetratricopeptide repeat domain 17 2.00908
MNT MAX network transcriptional repressor 2.00815
YPEL5 yippee-like 5 (Drosophila) 2.00566
ZYX zyxin 2.00138

decreased expression

Symbol Name Standardized Value
ISOC1 isochorismatase domain containing 1 -8.87224
PCCB propionyl CoA carboxylase, beta polypeptide -8.48775
FGFR4 fibroblast growth factor receptor 4 -8.22037
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -7.81629
RPIA ribose 5-phosphate isomerase A -7.48411
PROS1 protein S (alpha) -7.39452
PSRC1 proline/serine-rich coiled-coil 1 -7.00318
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -6.87761
TRIB3 tribbles pseudokinase 3 -6.71886
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -6.66495
PYCR1 pyrroline-5-carboxylate reductase 1 -6.45408
NIPSNAP1 nipsnap homolog 1 (C. elegans) -6.4373
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -6.22337
ENOPH1 enolase-phosphatase 1 -6.21829
TCTN1 tectonic family member 1 -5.98952
ICAM3 intercellular adhesion molecule 3 -5.98865
RSU1 Ras suppressor protein 1 -5.89955
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -5.84962
PLS1 plastin 1 -5.83951
AURKB aurora kinase B -5.75613
MNAT1 MNAT CDK-activating kinase assembly factor 1 -5.75559
CDC20 cell division cycle 20 -5.72093
HMGA2 high mobility group AT-hook 2 -5.70072
CCNA2 cyclin A2 -5.61567
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -5.46916
LBR lamin B receptor -5.4673
PLK1 polo-like kinase 1 -5.42051
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -5.41321
PGM1 phosphoglucomutase 1 -5.41256
PARP1 poly (ADP-ribose) polymerase 1 -5.2906
MYC v-myc avian myelocytomatosis viral oncogene homolog -5.23875
CCNB2 cyclin B2 -5.20916
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -5.15438
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -5.06747
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -5.04369
PECR peroxisomal trans-2-enoyl-CoA reductase -5.0259
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -4.97239
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -4.83037
CDK1 cyclin-dependent kinase 1 -4.72077
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -4.70277
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -4.5731
STMN1 stathmin 1 -4.50364
C2CD5 C2 calcium-dependent domain containing 5 -4.48441
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -4.45594
PCNA proliferating cell nuclear antigen -4.32635
USP6NL USP6 N-terminal like -4.31671
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -4.26027
PARP2 poly (ADP-ribose) polymerase 2 -4.23694
ANO10 anoctamin 10 -4.22575
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -4.1266
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -4.09697
MRPL12 mitochondrial ribosomal protein L12 -4.08444
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -4.08217
SOAT2 sterol O-acyltransferase 2 -4.00559
ANXA7 annexin A7 -3.90418
CDK4 cyclin-dependent kinase 4 -3.90335
HEATR1 HEAT repeat containing 1 -3.86673
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -3.83739
PXMP2 peroxisomal membrane protein 2, 22kDa -3.83518
PHKB phosphorylase kinase, beta -3.73743
CASP7 caspase 7, apoptosis-related cysteine peptidase -3.72965
ELP4 elongator acetyltransferase complex subunit 4 -3.72881
TMA16 translation machinery associated 16 homolog (S. cerevisiae) -3.6594
RFC2 replication factor C (activator 1) 2, 40kDa -3.63311
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -3.62428
CCNB1 cyclin B1 -3.62171
UGDH UDP-glucose 6-dehydrogenase -3.61624
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 -3.54395
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -3.53299
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -3.49823
PPID peptidylprolyl isomerase D -3.49391
SLC35F2 solute carrier family 35, member F2 -3.48539
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta -3.45706
NHP2 NHP2 ribonucleoprotein -3.40961
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -3.40784
DENND2D DENN/MADD domain containing 2D -3.40272
BLMH bleomycin hydrolase -3.38428
AP1AR adaptor-related protein complex 1 associated regulatory protein -3.36612
UBE2C ubiquitin-conjugating enzyme E2C -3.34711
HACD3 3-hydroxyacyl-CoA dehydratase 3 -3.33863
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -3.33381
CHEK1 checkpoint kinase 1 -3.31603
DNAAF2 dynein, axonemal, assembly factor 2 -3.31498
ALDOC aldolase C, fructose-bisphosphate -3.30574
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -3.24694
PGAM4 phosphoglycerate mutase family member 4 -3.23501
NFIL3 nuclear factor, interleukin 3 regulated -3.20118
ADI1 acireductone dioxygenase 1 -3.18386
MELK maternal embryonic leucine zipper kinase -3.17605
THAP11 THAP domain containing 11 -3.14051
HADH hydroxyacyl-CoA dehydrogenase -3.13104
FKBP3 FK506 binding protein 3, 25kDa -3.12976
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -3.12619
MOCS2 molybdenum cofactor synthesis 2 -3.12468
HDAC2 histone deacetylase 2 -3.12198
ZNF83 zinc finger protein 83 -3.11583
SPDEF SAM pointed domain containing ETS transcription factor -3.11153
NUP93 nucleoporin 93kDa -3.10501
LOC112694756 uncharaterized LOC112694756 -3.1046
TK1 thymidine kinase 1, soluble -3.10459
TMOD3 tropomodulin 3 (ubiquitous) -3.10388
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -3.0949
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -3.05461
GINS2 GINS complex subunit 2 (Psf2 homolog) -3.03291
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) -3.02263
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 -2.99519
HAT1 histone acetyltransferase 1 -2.98379
LYRM1 LYR motif containing 1 -2.97515
TMEM97 transmembrane protein 97 -2.95397
BZW2 basic leucine zipper and W2 domains 2 -2.92327
AMDHD2 amidohydrolase domain containing 2 -2.92012
CRELD2 cysteine-rich with EGF-like domains 2 -2.91728
RFC4 replication factor C (activator 1) 4, 37kDa -2.91532
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 -2.89418
RGS7 regulator of G-protein signaling 7 -2.89085
PAH phenylalanine hydroxylase -2.88719
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -2.88598
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -2.88441
SLC30A10 solute carrier family 30, member 10 -2.88187
BIRC5 baculoviral IAP repeat containing 5 -2.88042
GCSH glycine cleavage system protein H (aminomethyl carrier) -2.8664
LIPC lipase, hepatic -2.86293
AGMAT agmatine ureohydrolase (agmatinase) -2.86029
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H -2.85707
MRPL3 mitochondrial ribosomal protein L3 -2.84498
CXCL6 chemokine (C-X-C motif) ligand 6 -2.84364
CDK14 cyclin-dependent kinase 14 -2.84131
ADH6 alcohol dehydrogenase 6 (class V) -2.83493
NUP133 nucleoporin 133kDa -2.82423
ANAPC15 anaphase promoting complex subunit 15 -2.81128
MRPS7 mitochondrial ribosomal protein S7 -2.80208
MSMO1 methylsterol monooxygenase 1 -2.8016
STAP2 signal transducing adaptor family member 2 -2.80023
NUBPL nucleotide binding protein-like -2.79974
MEX3D mex-3 RNA binding family member D -2.76243
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.75817
SEPTIN11 septin 11 -2.75644
CRIPTO3 cripto, EGF-CFC family member 3 -2.74684
DUT deoxyuridine triphosphatase -2.74491
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) -2.72061
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -2.72009
FAIM Fas apoptotic inhibitory molecule -2.71949
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.71601
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 -2.71332
ECH1 enoyl CoA hydratase 1, peroxisomal -2.70638
MYL9 myosin, light chain 9, regulatory -2.70346
A1CF APOBEC1 complementation factor -2.69121
EGF epidermal growth factor -2.68339
NT5DC2 5'-nucleotidase domain containing 2 -2.68158
KCTD20 potassium channel tetramerization domain containing 20 -2.67861
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 -2.67434
MRPL39 mitochondrial ribosomal protein L39 -2.66734
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -2.66726
MCTS1 malignant T cell amplified sequence 1 -2.65588
MYLK3 myosin light chain kinase 3 -2.64693
RIT2 Ras-like without CAAX 2 -2.64488
DRC9 dynein regulatory complex subunit 9 -2.64414
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 -2.63939
IDI1 isopentenyl-diphosphate delta isomerase 1 -2.63899
HSPE1 heat shock 10kDa protein 1 -2.63857
MSRA methionine sulfoxide reductase A -2.63586
MRPS30 mitochondrial ribosomal protein S30 -2.6356
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 -2.63055
LARS1 leucyl-tRNA synthetase 1 -2.6299
FBXO5 F-box protein 5 -2.62599
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -2.60816
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa -2.6063
FHL2 four and a half LIM domains 2 -2.60599
UXT ubiquitously-expressed, prefoldin-like chaperone -2.60055
FZD4 frizzled class receptor 4 -2.59628
POLR1F RNA polymerase I subunit F -2.59323
THOC7 THO complex 7 -2.59068
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -2.58321
GNAS GNAS complex locus -2.58214
GIPC2 GIPC PDZ domain containing family, member 2 -2.57929
APOE apolipoprotein E -2.57753
ANO3 anoctamin 3 -2.57447
SERP1 stress-associated endoplasmic reticulum protein 1 -2.57339
GCA grancalcin, EF-hand calcium binding protein -2.57133
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta -2.56952
B4GAT1 beta-1,4-glucuronyltransferase 1 -2.56622
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) -2.56549
OSBPL10 oxysterol binding protein-like 10 -2.56084
NR1H4 nuclear receptor subfamily 1, group H, member 4 -2.55518
GJB1 gap junction protein, beta 1, 32kDa -2.55239
DCPH1 damage control phosphatase 1 -2.54868
EIF3I eukaryotic translation initiation factor 3, subunit I -2.53854
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 -2.53469
KIF4A kinesin family member 4A -2.52508
CADPS2 Ca++-dependent secretion activator 2 -2.51959
GMDS GDP-mannose 4,6-dehydratase -2.5145
AK4 adenylate kinase 4 -2.51128
FZD7 frizzled class receptor 7 -2.50958
NUCB2 nucleobindin 2 -2.50841
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase -2.50738
TIPIN TIMELESS interacting protein -2.50525
VDAC1 voltage-dependent anion channel 1 -2.4992
RPL36AL ribosomal protein L36a-like -2.49826
CEP83 centrosomal protein 83kDa -2.49677
OIP5 Opa interacting protein 5 -2.49465
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -2.49316
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -2.49252
TMX1 thioredoxin-related transmembrane protein 1 -2.49154
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa -2.48696
HSPD1 heat shock 60kDa protein 1 (chaperonin) -2.48418
WDR18 WD repeat domain 18 -2.48237
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) -2.47922
AIG1 androgen-induced 1 -2.47819
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -2.47348
RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae) -2.46977
MIS18A MIS18 kinetochore protein A -2.46861
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 -2.4661
TOMM70 translocase of outer mitochondrial membrane 70 -2.46608
ECT2 epithelial cell transforming 2 -2.46485
MTTP microsomal triglyceride transfer protein -2.46169
TBC1D16 TBC1 domain family, member 16 -2.46115
SAA4 serum amyloid A4, constitutive -2.45864
PBK PDZ binding kinase -2.45453
PTGES3 prostaglandin E synthase 3 (cytosolic) -2.4543
ASGR1 asialoglycoprotein receptor 1 -2.454
GPC5 glypican 5 -2.45122
PDHX pyruvate dehydrogenase complex, component X -2.44597
VIL1 villin 1 -2.44393
APIP APAF1 interacting protein -2.44011
SRP72 signal recognition particle 72kDa -2.43731
TUBB4A tubulin, beta 4A class IVa -2.43693
CDKN3 cyclin-dependent kinase inhibitor 3 -2.43175
SMPX small muscle protein, X-linked -2.42755
NUP37 nucleoporin 37kDa -2.42447
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 -2.42365
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) -2.42005
GGCT gamma-glutamylcyclotransferase -2.41809
CNKSR2 connector enhancer of kinase suppressor of Ras 2 -2.41763
ACOX2 acyl-CoA oxidase 2, branched chain -2.41335
FABP7 fatty acid binding protein 7, brain -2.41258
GTF2A2 general transcription factor IIA, 2, 12kDa -2.41202
CASP3 caspase 3, apoptosis-related cysteine peptidase -2.40699
NCF4 neutrophil cytosolic factor 4, 40kDa -2.40639
TRDN triadin -2.40374
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.40371
CRK v-crk avian sarcoma virus CT10 oncogene homolog -2.39801
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -2.39768
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -2.39686
USP1 ubiquitin specific peptidase 1 -2.39681
HIBCH 3-hydroxyisobutyryl-CoA hydrolase -2.39266
RBM3 RNA binding motif (RNP1, RRM) protein 3 -2.38973
OPCML opioid binding protein/cell adhesion molecule-like -2.38822
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -2.38615
PPA2 pyrophosphatase (inorganic) 2 -2.38333
SKIC8 SKI8 subunit of superkiller complex -2.38161
CCT8 chaperonin containing TCP1, subunit 8 (theta) -2.3813
EXTL2 exostosin-like glycosyltransferase 2 -2.38102
GET1 guided entry of tail-anchored proteins factor 1 -2.38016
COL1A2 collagen, type I, alpha 2 -2.3784
TLR4 toll-like receptor 4 -2.37607
TOP2A topoisomerase (DNA) II alpha 170kDa -2.37345
FCN1 ficolin (collagen/fibrinogen domain containing) 1 -2.37059
HMGB2 high mobility group box 2 -2.36728
LRRC59 leucine rich repeat containing 59 -2.36388
SEC13 SEC13 homolog (S. cerevisiae) -2.36282
RHOBTB1 Rho-related BTB domain containing 1 -2.35998
DHCR24 24-dehydrocholesterol reductase -2.35993
LMNB1 lamin B1 -2.35926
TOP2B topoisomerase (DNA) II beta 180kDa -2.35879
ERBB3 erb-b2 receptor tyrosine kinase 3 -2.35845
MSH2 mutS homolog 2 -2.35827
FABP1 fatty acid binding protein 1, liver -2.35368
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -2.35303
RPS5 ribosomal protein S5 -2.35028
FCF1 FCF1 rRNA-processing protein -2.3497
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 -2.34623
LIAS lipoic acid synthetase -2.34446
AMBP alpha-1-microglobulin/bikunin precursor -2.33116
ALOX5AP arachidonate 5-lipoxygenase-activating protein -2.32849
COL3A1 collagen, type III, alpha 1 -2.32673
BTBD8 BTB (POZ) domain containing 8 -2.3259
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum) -2.32314
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 -2.32284
PSPH phosphoserine phosphatase -2.31837
ZNF835 zinc finger protein 835 -2.31809
CTNND2 catenin (cadherin-associated protein), delta 2 -2.31672
APOC3 apolipoprotein C-III -2.315
CYB5B cytochrome b5 type B (outer mitochondrial membrane) -2.31321
CBX3 chromobox homolog 3 -2.31058
APOM apolipoprotein M -2.30957
TFB1M transcription factor B1, mitochondrial -2.30858
MRPS27 mitochondrial ribosomal protein S27 -2.30796
DBR1 debranching RNA lariats 1 -2.30706
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) -2.29873
TRAPPC3 trafficking protein particle complex 3 -2.29467
ANXA6 annexin A6 -2.29263
CFHR5 complement factor H-related 5 -2.29163
VSNL1 visinin-like 1 -2.28932
LRRC2 leucine rich repeat containing 2 -2.28573
COPB2 coatomer protein complex, subunit beta 2 (beta prime) -2.28042
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila) -2.27742
CLIC4 chloride intracellular channel 4 -2.27575
BFSP2 beaded filament structural protein 2, phakinin -2.27501
EXOSC8 exosome component 8 -2.27438
CETN3 centrin, EF-hand protein, 3 -2.2738
MYO10 myosin X -2.27297
BRD7 bromodomain containing 7 -2.2724
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -2.26874
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) -2.26386
SDF2L1 stromal cell-derived factor 2-like 1 -2.26111
PF4V1 platelet factor 4 variant 1 -2.2568
DCK deoxycytidine kinase -2.25632
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -2.24717
EBAG9 estrogen receptor binding site associated, antigen, 9 -2.24331
RAPSN receptor-associated protein of the synapse -2.24277
FHIT fragile histidine triad -2.24154
CPB2 carboxypeptidase B2 (plasma) -2.2406
VPS26C VPS26 endosomal protein sorting factor C -2.23793
VCAM1 vascular cell adhesion molecule 1 -2.23718
ELAVL1 ELAV like RNA binding protein 1 -2.23299
COPZ1 coatomer protein complex, subunit zeta 1 -2.23238
AHSG alpha-2-HS-glycoprotein -2.2258
CNN3 calponin 3, acidic -2.22531
NME1 NME/NM23 nucleoside diphosphate kinase 1 -2.22494
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 -2.22321
KIF5A kinesin family member 5A -2.22273
MAPK6 mitogen-activated protein kinase 6 -2.22266
GALK2 galactokinase 2 -2.2223
HPR haptoglobin-related protein -2.22142
PGAP2 post-GPI attachment to proteins 2 -2.21917
CDC25B cell division cycle 25B -2.21453
QPRT quinolinate phosphoribosyltransferase -2.21316
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6 -2.21284
PEX5L peroxisomal biogenesis factor 5-like -2.21197
MNDA myeloid cell nuclear differentiation antigen -2.21053
MSH6 mutS homolog 6 -2.20758
S100A8 S100 calcium binding protein A8 -2.20712
MRPL44 mitochondrial ribosomal protein L44 -2.20687
RPN1 ribophorin I -2.2068
CCL24 chemokine (C-C motif) ligand 24 -2.19923
ITPKA inositol-trisphosphate 3-kinase A -2.19861
EBNA1BP2 EBNA1 binding protein 2 -2.19808
SORD sorbitol dehydrogenase -2.19363
CAMKMT calmodulin-lysine N-methyltransferase -2.19156
GEMIN2 gem (nuclear organelle) associated protein 2 -2.19002
RMI1 RecQ mediated genome instability 1 -2.18804
MRTO4 mRNA turnover 4 homolog (S. cerevisiae) -2.18771
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.18688
CCDC170 coiled-coil domain containing 170 -2.18576
CKS2 CDC28 protein kinase regulatory subunit 2 -2.18482
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 -2.18258
KRT36 keratin 36, type I -2.18102
DHFR dihydrofolate reductase -2.1797
PALS1 protein associated with LIN7 1, MAGUK p55 family member -2.17924
MYL1 myosin, light chain 1, alkali; skeletal, fast -2.17683
LYZ lysozyme -2.17591
IMPACT impact RWD domain protein -2.17423
GAS2 growth arrest-specific 2 -2.17194
LRRTM4 leucine rich repeat transmembrane neuronal 4 -2.16732
SYNPO2L synaptopodin 2-like -2.16554
AURKA aurora kinase A -2.16423
PTPRK protein tyrosine phosphatase, receptor type, K -2.16401
ZHX2 zinc fingers and homeoboxes 2 -2.16023
GATA6 GATA binding protein 6 -2.15962
MBL2 mannose-binding lectin (protein C) 2, soluble -2.15944
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 -2.15818
DNM3 dynamin 3 -2.14903
CANX calnexin -2.14864
GSTK1 glutathione S-transferase kappa 1 -2.14654
PROX1 prospero homeobox 1 -2.1419
RTN3 reticulon 3 -2.13931
WDHD1 WD repeat and HMG-box DNA binding protein 1 -2.13898
LARS2 leucyl-tRNA synthetase 2, mitochondrial -2.1354
SPC25 SPC25, NDC80 kinetochore complex component -2.13535
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -2.1353
IREB2 iron-responsive element binding protein 2 -2.13382
AKR1D1 aldo-keto reductase family 1, member D1 -2.13292
UBE3C ubiquitin protein ligase E3C -2.13058
SIPA1L1 signal-induced proliferation-associated 1 like 1 -2.13055
CDC6 cell division cycle 6 -2.12746
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6 -2.12723
BUB1 BUB1 mitotic checkpoint serine/threonine kinase -2.12677
ACYP1 acylphosphatase 1, erythrocyte (common) type -2.12645
SFXN1 sideroflexin 1 -2.1262
FIRRM FIGNL1 interacting regulator of recombination and mitosis -2.12309
PKP2 plakophilin 2 -2.11989
BSN bassoon presynaptic cytomatrix protein -2.11827
SPAG4 sperm associated antigen 4 -2.11629
PDCD5 programmed cell death 5 -2.11589
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.11577
VRK1 vaccinia related kinase 1 -2.11489
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -2.11457
SPIN2B spindlin family, member 2B -2.11345
RUVBL1 RuvB-like AAA ATPase 1 -2.11141
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) -2.11106
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.11026
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa -2.10853
C1QTNF3 C1q and tumor necrosis factor related protein 3 -2.10622
MRPL48 mitochondrial ribosomal protein L48 -2.1051
CACYBP calcyclin binding protein -2.10426
LRRTM2 leucine rich repeat transmembrane neuronal 2 -2.10382
ALDH1B1 aldehyde dehydrogenase 1 family, member B1 -2.10219
NASP nuclear autoantigenic sperm protein (histone-binding) -2.09932
USP46 ubiquitin specific peptidase 46 -2.09763
NNT nicotinamide nucleotide transhydrogenase -2.09715
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4 -2.09548
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 -2.09328
MRPL19 mitochondrial ribosomal protein L19 -2.09248
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6 -2.09181
MRPS17 mitochondrial ribosomal protein S17 -2.09131
ANK2 ankyrin 2, neuronal -2.09026
SNRPA small nuclear ribonucleoprotein polypeptide A -2.08971
SNCB synuclein, beta -2.0828
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.08222
SNX5 sorting nexin 5 -2.07983
DSCC1 DNA replication and sister chromatid cohesion 1 -2.07543
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae) -2.07422
GLRX5 glutaredoxin 5 -2.07117
SNTG1 syntrophin, gamma 1 -2.07017
ANAPC10 anaphase promoting complex subunit 10 -2.06717
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) -2.06487
PEBP1 phosphatidylethanolamine binding protein 1 -2.0639
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 -2.06234
KLHL4 kelch-like family member 4 -2.06099
ELMO1 engulfment and cell motility 1 -2.0609
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -2.05957
LATS1 large tumor suppressor kinase 1 -2.05947
GUF1 GUF1 GTPase homolog (S. cerevisiae) -2.05939
SYN2 synapsin II -2.05933
APOA2 apolipoprotein A-II -2.05725
FBXO7 F-box protein 7 -2.05631
ZNF660-ZNF197 ZNF660-ZNF197 readthrough -2.05474
UBA5 ubiquitin-like modifier activating enzyme 5 -2.05414
USO1 USO1 vesicle transport factor -2.05168
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 -2.04694
PPEF2 protein phosphatase, EF-hand calcium binding domain 2 -2.0461
ENAH enabled homolog (Drosophila) -2.04516
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -2.04504
ITGB5 integrin, beta 5 -2.04126
APOA1 apolipoprotein A-I -2.04078
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 -2.03665
MCM6 minichromosome maintenance complex component 6 -2.03629
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1 -2.0358
ANKRD34C ankyrin repeat domain 34C -2.03462
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.03179
TMEM243 transmembrane protein 243, mitochondrial -2.02782
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5 -2.02776
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae) -2.02402
DEFA3 defensin, alpha 3, neutrophil-specific -2.02003
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 -2.0179
SCN1A sodium channel, voltage gated, type I alpha subunit -2.01762
CFHR2 complement factor H-related 2 -2.01689
LAGE3 L antigen family, member 3 -2.01347
CHAF1B chromatin assembly factor 1, subunit B (p60) -2.01112
TOX3 TOX high mobility group box family member 3 -2.0067
THY1 Thy-1 cell surface antigen -2.00636
ATP5IF1 ATP synthase inhibitory factor subunit 1 -2.00503
CNTN5 contactin 5 -2.00472
SNRPF small nuclear ribonucleoprotein polypeptide F -2.00005