CRCGN013_HEPG2_24H:K06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description o-phenylenediamine.2hcl 1.27 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

453 genes differentially expressed following the CRCGN013_HEPG2_24H:K06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CDPF1 cysteine-rich, DPF motif domain containing 1 10.0
CNPY3 canopy FGF signaling regulator 3 9.19561
LRP10 low density lipoprotein receptor-related protein 10 8.72418
INPP1 inositol polyphosphate-1-phosphatase 8.6467
BLCAP bladder cancer associated protein 8.63392
ABHD4 abhydrolase domain containing 4 8.1474
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 7.9365
DDB2 damage-specific DNA binding protein 2, 48kDa 7.88855
MICALL1 MICAL-like 1 7.71291
TUBB6 tubulin, beta 6 class V 6.53395
GPC1 glypican 1 6.16634
ASCC3 activating signal cointegrator 1 complex subunit 3 5.95134
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 5.7947
KIFBP kinesin family binding protein 5.44258
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 5.39863
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 5.21854
SMAD3 SMAD family member 3 5.09394
TIMP2 TIMP metallopeptidase inhibitor 2 4.8849
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 4.86878
DUSP14 dual specificity phosphatase 14 4.74859
MVP major vault protein 4.73913
CTSL cathepsin L 4.64001
FOXJ3 forkhead box J3 4.59732
NPDC1 neural proliferation, differentiation and control, 1 4.58554
CCDC92 coiled-coil domain containing 92 4.57489
TIAM1 T-cell lymphoma invasion and metastasis 1 4.42104
IL4R interleukin 4 receptor 4.34265
MINDY1 MINDY lysine 48 deubiquitinase 1 4.27227
RALGDS ral guanine nucleotide dissociation stimulator 4.2331
FOSL1 FOS-like antigen 1 4.08163
FDXR ferredoxin reductase 4.04351
GATA2 GATA binding protein 2 3.89648
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 3.87661
PHLDA3 pleckstrin homology-like domain, family A, member 3 3.8557
KEAP1 kelch-like ECH-associated protein 1 3.78046
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.76969
SQOR sulfide quinone oxidoreductase 3.76161
IGFBP3 insulin-like growth factor binding protein 3 3.76089
TIGAR TP53 induced glycolysis regulatory phosphatase 3.72968
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 3.63908
PLK3 polo-like kinase 3 3.62987
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 3.57296
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 3.56964
E2F2 E2F transcription factor 2 3.40946
PRKCQ protein kinase C, theta 3.37218
HLA-DMA major histocompatibility complex, class II, DM alpha 3.33863
CGRRF1 cell growth regulator with ring finger domain 1 3.30608
TERF2IP telomeric repeat binding factor 2, interacting protein 3.30389
SKIC2 SKI2 subunit of superkiller complex 3.29382
LCN2 lipocalin 2 3.28834
MTERF3 mitochondrial transcription termination factor 3 3.27917
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 3.23288
IER3 immediate early response 3 3.20242
ADGRE5 adhesion G protein-coupled receptor E5 3.19624
XPC xeroderma pigmentosum, complementation group C 3.18708
JADE2 jade family PHD finger 2 3.17924
ADGRG1 adhesion G protein-coupled receptor G1 3.17681
DUSP3 dual specificity phosphatase 3 3.11456
LIF leukemia inhibitory factor 3.10882
DHRS7 dehydrogenase/reductase (SDR family) member 7 3.08095
SLC35F6 solute carrier family 35, member F6 3.05833
MAPK13 mitogen-activated protein kinase 13 3.04827
DUSP6 dual specificity phosphatase 6 3.03289
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C 3.03085
MYLK myosin light chain kinase 3.01495
BAX BCL2-associated X protein 3.0126
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 2.9652
EPHA2 EPH receptor A2 2.95496
VAT1 vesicle amine transport 1 2.95088
KHDC4 KH domain containing 4, pre-mRNA splicing factor 2.91677
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 2.86009
PNKP polynucleotide kinase 3'-phosphatase 2.84812
TXNRD1 thioredoxin reductase 1 2.79222
FPGS folylpolyglutamate synthase 2.79074
STX1A syntaxin 1A (brain) 2.77991
TOR1A torsin family 1, member A (torsin A) 2.77636
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 2.74969
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.74178
INTS3 integrator complex subunit 3 2.74077
AEN apoptosis enhancing nuclease 2.7328
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2.70441
MCOLN1 mucolipin 1 2.70255
RABGGTA Rab geranylgeranyltransferase, alpha subunit 2.67549
TRIP12 thyroid hormone receptor interactor 12 2.67035
BECN1 beclin 1, autophagy related 2.66306
GALE UDP-galactose-4-epimerase 2.63511
PROCR protein C receptor, endothelial 2.625
TRIM22 tripartite motif containing 22 2.62351
CCND3 cyclin D3 2.62349
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 2.60892
CDK5RAP1 CDK5 regulatory subunit associated protein 1 2.60703
SQSTM1 sequestosome 1 2.60581
SCPEP1 serine carboxypeptidase 1 2.58162
BYSL bystin-like 2.57081
GADD45A growth arrest and DNA-damage-inducible, alpha 2.56932
ASCC2 activating signal cointegrator 1 complex subunit 2 2.56781
UBE2A ubiquitin-conjugating enzyme E2A 2.55691
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 2.55634
BTG2 BTG family, member 2 2.53875
CASC3 cancer susceptibility candidate 3 2.53259
PORCN porcupine homolog (Drosophila) 2.5282
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) 2.52765
GBA1 glucosylceramidase beta 1 2.49911
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 2.47314
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.45406
DDR1 discoidin domain receptor tyrosine kinase 1 2.44154
DYNLT3 dynein, light chain, Tctex-type 3 2.43325
CHD8 chromodomain helicase DNA binding protein 8 2.4137
MICU2 mitochondrial calcium uptake 2 2.3974
TSC22D4 TSC22 domain family, member 4 2.39736
FSTL3 follistatin-like 3 (secreted glycoprotein) 2.39106
TRIM8 tripartite motif containing 8 2.38704
KLK2 kallikrein-related peptidase 2 2.38096
LOXL1 lysyl oxidase-like 1 2.37831
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 2.37286
ZNF195 zinc finger protein 195 2.37098
TRIM62 tripartite motif containing 62 2.36031
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 2.34888
KDM5A lysine (K)-specific demethylase 5A 2.34559
RIN1 Ras and Rab interactor 1 2.33721
ERCC5 excision repair cross-complementation group 5 2.33353
CDIP1 cell death-inducing p53 target 1 2.33125
GSDME gasdermin E 2.32611
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 2.32011
SPATA20 spermatogenesis associated 20 2.31895
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 2.30876
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 2.30476
PYGB phosphorylase, glycogen; brain 2.29815
OFD1 oral-facial-digital syndrome 1 2.29767
MMP1 matrix metallopeptidase 1 2.2903
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 2.28154
CEL carboxyl ester lipase 2.27999
TBX3 T-box 3 2.27881
RCOR3 REST corepressor 3 2.27429
MAD2L1BP MAD2L1 binding protein 2.2725
ZMAT3 zinc finger, matrin-type 3 2.27226
TRIAP1 TP53 regulated inhibitor of apoptosis 1 2.26892
COG4 component of oligomeric golgi complex 4 2.2663
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 2.2635
ELAC2 elaC ribonuclease Z 2 2.25892
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14 2.25654
CTF1 cardiotrophin 1 2.25642
BEST1 bestrophin 1 2.25588
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.25305
TNIP1 TNFAIP3 interacting protein 1 2.24971
HBEGF heparin-binding EGF-like growth factor 2.24836
HDAC7 histone deacetylase 7 2.24626
ZNF219 zinc finger protein 219 2.24208
CES2 carboxylesterase 2 2.2412
RPRD2 regulation of nuclear pre-mRNA domain containing 2 2.22961
RAP1GAP RAP1 GTPase activating protein 2.21703
CCND2 cyclin D2 2.21563
DGKA diacylglycerol kinase, alpha 80kDa 2.20415
MICALL2 MICAL-like 2 2.19988
TREM1 triggering receptor expressed on myeloid cells 1 2.19697
KANSL2 KAT8 regulatory NSL complex subunit 2 2.1951
RALB v-ral simian leukemia viral oncogene homolog B 2.19242
CCNL2 cyclin L2 2.182
GRN granulin 2.18022
CHMP6 charged multivesicular body protein 6 2.17923
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 2.1673
ZDHHC24 zinc finger, DHHC-type containing 24 2.16721
MSMB microseminoprotein, beta- 2.16582
CEMIP2 cell migration inducing hyaluronidase 2 2.16203
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 2.14329
ADNP activity-dependent neuroprotector homeobox 2.14115
IFNG interferon, gamma 2.1386
THSD1 thrombospondin, type I, domain containing 1 2.13523
PARP4 poly (ADP-ribose) polymerase family, member 4 2.13488
LY6G6F-LY6G6D LY6G6F-LY6G6D readthrough 2.13359
PRKCD protein kinase C, delta 2.13214
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa 2.13074
ADRB2 adrenoceptor beta 2, surface 2.12872
IQSEC2 IQ motif and Sec7 domain 2 2.12454
BZW2 basic leucine zipper and W2 domains 2 2.11607
MAPK12 mitogen-activated protein kinase 12 2.11595
ROGDI rogdi homolog (Drosophila) 2.11459
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 2.11417
AOPEP aminopeptidase O (putative) 2.11217
MEA1 male-enhanced antigen 1 2.10854
MUC13 mucin 13, cell surface associated 2.08451
MAP7D1 MAP7 domain containing 1 2.08197
KLHL36 kelch-like family member 36 2.0741
FASN fatty acid synthase 2.06254
MUTYH mutY homolog 2.06234
FAM50A family with sequence similarity 50, member A 2.05915
CDC45 cell division cycle 45 2.05904
SARM1 sterile alpha and TIR motif containing 1 2.05401
COL4A5 collagen, type IV, alpha 5 2.05112
PI4KB phosphatidylinositol 4-kinase, catalytic, beta 2.0462
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 2.04421
AOAH acyloxyacyl hydrolase (neutrophil) 2.02711
COG7 component of oligomeric golgi complex 7 2.02543
DCTN2 dynactin 2 (p50) 2.02288
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein 2.02082
GPATCH8 G patch domain containing 8 2.01415
GCLC glutamate-cysteine ligase, catalytic subunit 2.01335
ATG9A autophagy related 9A 2.01136
VPS9D1 VPS9 domain containing 1 2.00971
ATG2A autophagy related 2A 2.00831
ZNF79 zinc finger protein 79 2.00776
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 2.00401
TP53I3 tumor protein p53 inducible protein 3 2.0038

decreased expression

Symbol Name Standardized Value
FGFR4 fibroblast growth factor receptor 4 -7.73909
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -7.73405
ISOC1 isochorismatase domain containing 1 -7.25015
PECR peroxisomal trans-2-enoyl-CoA reductase -6.22531
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -6.09793
PLK1 polo-like kinase 1 -5.67176
ZW10 zw10 kinetochore protein -5.64698
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -5.60578
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -5.57157
CCNB2 cyclin B2 -5.31424
ALDOC aldolase C, fructose-bisphosphate -5.16547
PROS1 protein S (alpha) -5.04643
ICAM3 intercellular adhesion molecule 3 -4.98381
PYCR1 pyrroline-5-carboxylate reductase 1 -4.71947
TCTN1 tectonic family member 1 -4.6506
CCNA2 cyclin A2 -4.56018
PSRC1 proline/serine-rich coiled-coil 1 -4.40489
RPIA ribose 5-phosphate isomerase A -4.38738
ENOPH1 enolase-phosphatase 1 -4.35442
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -4.35353
ARID5B AT rich interactive domain 5B (MRF1-like) -4.33887
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -4.32765
STMN1 stathmin 1 -4.25023
AURKB aurora kinase B -4.19571
USP6NL USP6 N-terminal like -4.14403
LBR lamin B receptor -4.0549
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -4.03205
SOAT2 sterol O-acyltransferase 2 -4.0162
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -3.78057
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -3.66849
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -3.60693
MYC v-myc avian myelocytomatosis viral oncogene homolog -3.50962
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -3.46768
RSU1 Ras suppressor protein 1 -3.43888
ELP4 elongator acetyltransferase complex subunit 4 -3.41609
CDC20 cell division cycle 20 -3.41346
PCCB propionyl CoA carboxylase, beta polypeptide -3.34519
CDK1 cyclin-dependent kinase 1 -3.32147
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -3.20954
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -3.20719
DENND2D DENN/MADD domain containing 2D -3.18873
PEG10 paternally expressed 10 -3.18744
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -3.18332
CHEK1 checkpoint kinase 1 -3.17998
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -3.13276
A1CF APOBEC1 complementation factor -3.0922
E2F5 E2F transcription factor 5, p130-binding -3.08802
CRELD2 cysteine-rich with EGF-like domains 2 -3.06079
HADH hydroxyacyl-CoA dehydrogenase -2.98522
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -2.9697
NGRN neugrin, neurite outgrowth associated -2.96617
MAP7 microtubule-associated protein 7 -2.96252
ITGB1BP1 integrin beta 1 binding protein 1 -2.93399
MNAT1 MNAT CDK-activating kinase assembly factor 1 -2.88649
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -2.87559
C2CD5 C2 calcium-dependent domain containing 5 -2.87168
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.83261
PGM1 phosphoglucomutase 1 -2.81274
PPID peptidylprolyl isomerase D -2.7953
ARHGAP11A Rho GTPase activating protein 11A -2.79513
MPHOSPH6 M-phase phosphoprotein 6 -2.77404
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -2.76878
SLC35F2 solute carrier family 35, member F2 -2.76669
ANO3 anoctamin 3 -2.75671
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) -2.73611
PXMP2 peroxisomal membrane protein 2, 22kDa -2.71635
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -2.70149
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -2.69792
MOCS2 molybdenum cofactor synthesis 2 -2.68703
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 -2.65205
MRPL18 mitochondrial ribosomal protein L18 -2.64899
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -2.64324
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.64299
MSRA methionine sulfoxide reductase A -2.64274
SCD stearoyl-CoA desaturase (delta-9-desaturase) -2.63839
TRDMT1 tRNA aspartic acid methyltransferase 1 -2.63783
BIRC5 baculoviral IAP repeat containing 5 -2.62142
OIP5 Opa interacting protein 5 -2.60895
NFIL3 nuclear factor, interleukin 3 regulated -2.60093
TMA16 translation machinery associated 16 homolog (S. cerevisiae) -2.59409
IREB2 iron-responsive element binding protein 2 -2.58863
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 -2.58769
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -2.57931
NIPSNAP1 nipsnap homolog 1 (C. elegans) -2.56855
GMCL1 germ cell-less, spermatogenesis associated 1 -2.56813
PLS1 plastin 1 -2.56753
ELAVL2 ELAV like neuron-specific RNA binding protein 2 -2.56338
MAT1A methionine adenosyltransferase I, alpha -2.56267
ARF4 ADP-ribosylation factor 4 -2.53454
LOC124907782 dual specificity protein phosphatase 22 -2.50393
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) -2.49281
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -2.48959
AGXT alanine-glyoxylate aminotransferase -2.48536
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor -2.48449
AHSG alpha-2-HS-glycoprotein -2.4807
USP1 ubiquitin specific peptidase 1 -2.47737
TRIB3 tribbles pseudokinase 3 -2.46886
NUCB2 nucleobindin 2 -2.4607
CRK v-crk avian sarcoma virus CT10 oncogene homolog -2.45902
MYL9 myosin, light chain 9, regulatory -2.45469
CHKA choline kinase alpha -2.44969
NDST3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 -2.44115
NXT2 nuclear transport factor 2-like export factor 2 -2.43075
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -2.4267
ZCCHC4 zinc finger, CCHC domain containing 4 -2.42254
APOH apolipoprotein H (beta-2-glycoprotein I) -2.41398
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 -2.41394
LZTFL1 leucine zipper transcription factor-like 1 -2.4138
PRPF38B pre-mRNA processing factor 38B -2.41194
GNAS GNAS complex locus -2.41051
APOC3 apolipoprotein C-III -2.40255
HMGA2 high mobility group AT-hook 2 -2.39517
SNX3 sorting nexin 3 -2.38806
CETN3 centrin, EF-hand protein, 3 -2.38769
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa -2.38673
DHCR7 7-dehydrocholesterol reductase -2.38164
GAS2 growth arrest-specific 2 -2.38095
NHP2 NHP2 ribonucleoprotein -2.37473
CCDC85B coiled-coil domain containing 85B -2.36691
UXT ubiquitously-expressed, prefoldin-like chaperone -2.36024
HDAC2 histone deacetylase 2 -2.3519
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa -2.3481
HAT1 histone acetyltransferase 1 -2.34404
ZNF236 zinc finger protein 236 -2.33496
PLG plasminogen -2.3342
NUP93 nucleoporin 93kDa -2.33116
INCENP inner centromere protein antigens 135/155kDa -2.3294
ANGPTL8 angiopoietin like 8 -2.32263
KIF5A kinesin family member 5A -2.30869
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) -2.30869
BUB1 BUB1 mitotic checkpoint serine/threonine kinase -2.30409
ADH6 alcohol dehydrogenase 6 (class V) -2.29767
IDI1 isopentenyl-diphosphate delta isomerase 1 -2.29716
APOM apolipoprotein M -2.28832
ADI1 acireductone dioxygenase 1 -2.28126
AMBP alpha-1-microglobulin/bikunin precursor -2.27781
C5 complement component 5 -2.27566
TRPM3 transient receptor potential cation channel, subfamily M, member 3 -2.27371
PDIA5 protein disulfide isomerase family A, member 5 -2.26993
VASH2 vasohibin 2 -2.26923
MRPS18C mitochondrial ribosomal protein S18C -2.2662
PDHX pyruvate dehydrogenase complex, component X -2.26406
ENY2 enhancer of yellow 2 homolog (Drosophila) -2.26259
PODXL podocalyxin-like -2.26075
SERP1 stress-associated endoplasmic reticulum protein 1 -2.25991
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.2583
POLR1G RNA polymerase I subunit G -2.25776
PPP4C protein phosphatase 4, catalytic subunit -2.25702
ZNF652 zinc finger protein 652 -2.25611
WDHD1 WD repeat and HMG-box DNA binding protein 1 -2.25539
VPS26C VPS26 endosomal protein sorting factor C -2.2538
BLMH bleomycin hydrolase -2.24902
MPC1 mitochondrial pyruvate carrier 1 -2.24324
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6 -2.24168
ZHX2 zinc fingers and homeoboxes 2 -2.23455
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A -2.23318
RIDA reactive intermediate imine deaminase A homolog -2.22615
UGDH UDP-glucose 6-dehydrogenase -2.22111
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 -2.22049
PDGFRL platelet-derived growth factor receptor-like -2.21843
MSMO1 methylsterol monooxygenase 1 -2.21647
PAH phenylalanine hydroxylase -2.21446
GPC5 glypican 5 -2.21414
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 -2.21405
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 -2.21018
POU4F2 POU class 4 homeobox 2 -2.20742
AP3S1 adaptor-related protein complex 3, sigma 1 subunit -2.20398
HTD2 hydroxyacyl-thioester dehydratase type 2 -2.20241
ELP5 elongator acetyltransferase complex subunit 5 -2.20138
ACTR3B ARP3 actin-related protein 3 homolog B (yeast) -2.20073
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 -2.19696
EPB41L4B erythrocyte membrane protein band 4.1 like 4B -2.19381
UBA5 ubiquitin-like modifier activating enzyme 5 -2.18994
PUM3 pumilio RNA binding family member 3 -2.18762
COPB2 coatomer protein complex, subunit beta 2 (beta prime) -2.18649
PHF10 PHD finger protein 10 -2.18492
CCNC cyclin C -2.18386
MYOC myocilin, trabecular meshwork inducible glucocorticoid response -2.17917
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -2.17672
DUT deoxyuridine triphosphatase -2.1761
PCOLCE2 procollagen C-endopeptidase enhancer 2 -2.17604
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like -2.17349
PFDN6 prefoldin subunit 6 -2.16587
RAD51 RAD51 recombinase -2.1649
FAM76A family with sequence similarity 76, member A -2.1642
CPB2 carboxypeptidase B2 (plasma) -2.16054
MVD mevalonate (diphospho) decarboxylase -2.1597
SLC30A3 solute carrier family 30 (zinc transporter), member 3 -2.1588
REEP1 receptor accessory protein 1 -2.15553
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -2.15544
SKA1 spindle and kinetochore associated complex subunit 1 -2.1551
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1 -2.15143
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 -2.14894
VAV3 vav 3 guanine nucleotide exchange factor -2.14871
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -2.14159
ZIC1 Zic family member 1 -2.14083
SEC13 SEC13 homolog (S. cerevisiae) -2.14073
ICE2 interactor of little elongation complex ELL subunit 2 -2.14058
NR1H4 nuclear receptor subfamily 1, group H, member 4 -2.14026
KIF18A kinesin family member 18A -2.13563
SPIN2B spindlin family, member 2B -2.13325
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -2.12747
MCTP1 multiple C2 domains, transmembrane 1 -2.1252
CDKN3 cyclin-dependent kinase inhibitor 3 -2.12154
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 -2.12091
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 -2.11985
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -2.11641
TUBB4A tubulin, beta 4A class IVa -2.11017
RBMXL2 RNA binding motif protein, X-linked-like 2 -2.10988
GFUS GDP-L-fucose synthase -2.1068
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) -2.10498
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -2.1023
UPB1 ureidopropionase, beta -2.10193
MED21 mediator complex subunit 21 -2.10145
SGPP2 sphingosine-1-phosphate phosphatase 2 -2.10099
DCN decorin -2.09986
GNG3 guanine nucleotide binding protein (G protein), gamma 3 -2.0976
COL2A1 collagen, type II, alpha 1 -2.09551
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 -2.09515
UBE2L3 ubiquitin-conjugating enzyme E2L 3 -2.09221
GPR63 G protein-coupled receptor 63 -2.09093
RFC2 replication factor C (activator 1) 2, 40kDa -2.08937
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.08903
CDCA3 cell division cycle associated 3 -2.08681
EBF2 early B-cell factor 2 -2.07797
PCDHGA3 protocadherin gamma subfamily A, 3 -2.07669
WDR18 WD repeat domain 18 -2.06958
MAGOHB mago-nashi homolog B (Drosophila) -2.06567
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 -2.06361
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -2.05726
NFYB nuclear transcription factor Y, beta -2.05685
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 -2.04975
CFHR5 complement factor H-related 5 -2.04865
NEK4 NIMA-related kinase 4 -2.03883
EBAG9 estrogen receptor binding site associated, antigen, 9 -2.0375
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 -2.03711
NT5DC2 5'-nucleotidase domain containing 2 -2.03323
TCP1 t-complex 1 -2.03255
CDC6 cell division cycle 6 -2.02927
NRTN neurturin -2.029
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila) -2.02794
STK38L serine/threonine kinase 38 like -2.02699
GLYAT glycine-N-acyltransferase -2.02505
FHL2 four and a half LIM domains 2 -2.02194
CAMKMT calmodulin-lysine N-methyltransferase -2.02148
SQLE squalene epoxidase -2.0196
HNRNPM heterogeneous nuclear ribonucleoprotein M -2.01206
MTFR1 mitochondrial fission regulator 1 -2.00668
PLPBP pyridoxal phosphate binding protein -2.0037
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) -2.00084